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The development of oncolytic viruses has recently made great progress towards being available to cancer patients. With the breakthrough into clinics, it is crucial to analyze the existing clinical experience and use it as a basis for treatment improvements. Here we report clinical data from 290 patients treated with oncolytic adenovirus. Using clinical variables and treatment characteristics, we c
Low-energy electron diffraction, scanning tunneling microscopy, and photoelectron spectroscopy results from the submonolayer Sm- and Yb-induced surface structures are presented. Several similar metal-induced surface reconstructions are found to exist for Yb and Sm on Si(111) for low submonolayer coverages: 3×2, 5×1, and 7×1. At higher submonolayer coverage, Yb induces a 2×1 reconstruction while Sm
Introduction The conventional ECG is commonly used to screen for hypertrophic cardiomyopathy (HCM), but up to 25% of adults and possibly larger percentages of children with HCM have no distinctive abnormalities on the conventional ECG, whereas 5 to 15% of healthy young athletes do. Recently, a 5-min resting advanced 12-lead ECG test ("A-ECG score") showed superiority to pooled criteria from the st
Background: Many women of childbearing age are occupationally active, which leads to a large number of pregnancies potentially exposed to occupational exposures. Occupational noise has been identified as a risk factor for hearing impairment in adults. However, very few studies have assessed the effect of occupational noise on the fetus. Objectives: The aim of this study was to investigate whether
På 1970-talet infördes Sveriges första förbud mot insiderhandel, med syfte att upprätthålla ett högt förtroende för värdepappersmarknaden. Sedan tillkomsten har insiderlagstiftningen kritiserats kraftigt. Den främsta grunden för kritiken har varit det låga antalet fällande domar. En anledning till svårigheten att lagföra insiderbrott är att en stor mängd insiderinformation skickas mellan närståendSweden's first ban on insider trading was introduced in the 1970s. The aim of the legislation was to maintain high confidence in the securities market. Since then, the legal field has been subject to extensive critizism due to the low number of convictions. The difficulty of taking legal proceedings against insider crimes is due to many reasons; one being that a large amount of insider informa
Syftet med följande studie är att granska hur svensk lagstiftning hanterar nya former av integritetskränkningar som följer av den tekniska utvecklingen. Utredningen tar sikte på bestämmelsen BrB 4 kap. 6a§ om kränkande fotografering och undersöker huruvida dess syfte att skydda individers personliga integritet uppfylls. Begreppet integritet är omdiskuterat och svårdefinierat. För att möjliggöra enThe purpose of the following essay is to examine how the law handles new forms of integrity violations caused by the technological evolution. The study concentrates on Chapter 4, Section 6a, of the Swedish Penal Code concerning indecent photography. Therefore, the intension is to assess whether the regulation fulfills its purpose; to preserve privacy. The term privacy is considered difficult to de
Syftet med den här uppsatsen är dels att belysa kriminaliseringen av tidelag i Sverige ur ett rättshistoriskt perspektiv, dels att med ett kritiskt perspektiv granska de motiv som ligger bakom det förbud mot sexuella handlingar med djur som trädde i kraft i april 2014. Motiven till och samhällssituationen vid tidigare lagstiftning jämförs med motiven till nykriminaliseringen för att se hur rättsutThe purpose of this essay is to show how the Swedish legal system has dealt with bestiality. This is done by using a legal historical perspective. Also, the essay studies the motives behind the criminalization of sexual acts with animals that entered into force in April 2014. The motives behind earlier legislation as well as the society at that time are compared to the motives of the new criminali
Ocean acidification is a consequence of the anthropogenic release of carbon dioxide (CO2) to the atmosphere. When CO2 is dissolved in water it affects the composition of ions and lowers the pH of the water. As the partial CO2 pressure in the atmosphere increases a new balance is reached with the surface waters which causes the pH of the surface oceans to decrease. For small shallow seas this effec
Psykiskt störda lagöverträdare har länge särbehandlats i svensk rätt. Fram till brottsbalkens ikraftträdande år 1965 har psykiskt störda som saknat förståndets bruk befunnit sig i en sorts undantagssituation i förhållande till andra lagöverträdare, då de inte ådömts straffrättsligt ansvar på grund av otillräknelighet. Med brottsbalkens införande försvann tillräknelighetskravet för straffrättsligt
För människan är en grundläggande miljökvalitet en nödvändig förutsättning för liv och livskvalitet. Eftersom vi vill leva är miljökvalitet eftersträvansvärt. För människan är även förutsebarhet en viktig förutsättning då den gör det möjligt att planera sin tillvaro och känna trygghet. För att få förutsebarhet är juridik ett viktigt medel. Det kan dock finnas ett spänningsförhållande mellan juridiFor humankind, an elementary level of quality in the environment is a necessary precondition for life and life quality. Therefore, it is also desirable since we want to live. For humankind, foreseeability is also an important precondition since it makes it possible to plan one’s life and feel secure. In order to get foreseeability, law is an important means. However, there can be a tension between
The present study concerns the implementation of a voluntary job rotation program for individual and organizational development. In order to increase participation in job rotation programs, it is crucial to understand the phenomenon of non-participation. Accordingly, the present study aims to (a) identify reasons for non-participation from an employee perspective and (b) uncover possible hindrance
Ecological rehabilitation projects - as a form of reforestation interventions - are increasing worldwide and present an opportunity for climate change mitigation and supporting local livelihoods. Implemented in post-conflict situations, they are increasingly promoted as solutions for peace. Aiming at understanding their contributions to sustainability and peacebuilding, I examine proposed rehabili
Uppsatsens syfte är att ur ett rättssäkerhetsperspektiv undersöka frivillighetsrekvisitet i 6 kap. 1 § brottsbalken. Först genom att undersöka hur lagstiftaren be-skrivit rekvisitet i förarbetena och lagtexten för att sedan analysera hovrättsdomar som tillämpat det. Detta för att avgöra om kritiken gällande oförutsebarheten i lagstiftningen varit befogad. Diskussionen om frivillighet kom på allva
The use of land in the Swedish city of Lund is a question that has attracted a lot of attention in the last couple of years. The city is in need of expansion but ideas of where and how to accomplish this has differed until the release of the latest general plan which dictates that all major developments should be realized by densification. The city is surrounded by high value farmland which needs
The fear of crime is a negative emotional reaction of people to possible crimes, and there is sometimes a disparity between the actual crime rate and the fear of crime of people. Geographical researchers often combine the sketch map with the fear of crime to analyze the spatial pattern of the fear. The approaches of neogeography can possibly make the surveys with sketch map more effective and allo
I denna uppsats undersöks de möjligheter en våldsutsatt kvinna har att fysiskt åtskiljas ifrån en våldsutövande manlig partner i Sverige respektive Finland. Fokus i uppsatsen ligger vid sammanboende par. Genom studien har jag sökt efter att identifiera brister och styrkor i ländernas lagstiftning, för att sedan analysera huruvida och i vilken utsträckning lagstiftningen uppfyller ett våldsförebyggIn this thesis I examine what legal options a female victim of domestic violence has at her disposal in order to be physically separated from the perpetrator in Sweden and Finland, respectively. The subject of examination is a man and a woman in a relationship that are either married or romantic cohabitants. Through this study I have strived to identify the strengths and weaknesses in both the Swe
Den 1 juli i år införs det nya brottet involverande av en underårig i brottslighet i 16 kap. 5 a § brottsbalken. I propositionen Skärpta straff för brott i kriminella nätverk beskrivs den nya kriminaliseringens syfte vara att skydda samhället från att unga personer dras in i kriminella nätverk. För att en straffbestämmelse ska anses rättfärdigad finns det flera kriminaliseringsprinciper som den
Mitochondrial damage and dysfunction are associated with the aging process, and can be attributed to mutations in both nuclear and mitochondrial genes involved in cellular respiration. Mitochondrial DNA is particularly prone to damage due to its proximity to reactive oxygen species in the mitochondrial matrix. With the current advances in gene therapy studies for both inherited and acquired diseas
English as a second language (ESL) classrooms in Sweden constitute multicultural and social platforms where different language backgrounds and attitudes meet and where norms intersect, are contested and negotiated, creating possibilities for some, but limitations for others. The Swedish National Agency for Education promotes norm critical pedagogy (NCP) as a means to tackle degrading treatment and
