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Objectives Registries have been highlighted as means to improve quality of care. Here, we describe temporal trends in risk factors, lifestyle and preventive medication for patients after myocardial infarction (MI) registered in the quality registry Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART). D
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Activating Notch1 mutations have been reported in human T-line-age acute lymphoblastic leukemia (T-ALL) and lymphomas from genetically modified mice. We report that Notch1 is a prevalent and major mutational target in chemically induced mouse lymphoma. The regions of the gene that are frequently mutated are the heterodimerization domain and the N-terminal ligand-binding region, important for prote
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Betaine-homocysteine S-methyltransferase (BHMT) is a zinc-dependent methyltransferase that uses betaine as the methyl donor for the remethylation of homocysteine to form methionine. This reaction supports S-adenosylmethionine biosynthesis, which is required for hundreds of methylation reactions in humans. Herein we report that BHMT is activated by potassium ions with an apparent KM for K+ of about
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BACKGROUND: Prior research has established a positive association between the single-measured triglyceride-glucose (TyG) index and hypertension. Nevertheless, longitudinal studies addressing the enduring impact of TyG index on incident hypertension are lacking. This study sought to explore the association between cumulative TyG index (cum-TyG) and incident hypertension, especially obesity-related
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AIMS: Metformin has hitherto not been proven superior to other type 2 diabetes (T2D) medications for the prevention of organ complications. The aim of this study is to report baseline data and blinded interim analyses in the register-based randomised clinical trial (RRCT) SMARTEST, which compares metformin and the SGLT2 inhibitor dapagliflozin in early T2D. We also present learnings from the novel
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AimThe aim of this study was to investigate differences in mortality up to 1year of age in extremely preterm infants (before 27weeks) born in seven Swedish healthcare regions. MethodsNational prospective observational study of consecutively born, extremely preterm infants in Sweden 2004-2007. Mortality was compared between regions. Crude and adjusted odds ratios and 95% CI were calculated. Results
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BACKGROUND: Subtelomeric regions are gene rich and deletions in these chromosomal segments have been demonstrated to account for approximately 2.5% of patients displaying mental retardation with or without association of dysmorphic features. However, cases that report de novo terminal deletions on chromosome arm 15q are rare. METHODS: In this study we present the first example of a detailed molecu
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The metabolism of individual polyunsaturated fatty acids (PUFA) may be influenced differently by nutritional status and nutritional intake. In normal rats, radioactive arachidonic acid (20:4(n-6), is preferentially retained in tissue phospholipids compared to linoleic (18:2(n-6), or eicosapentaenoic acid (20:5(n-3). This study compares the fate of 20:4(n-6) and 20:5(n-3) acids in essential fatty a
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The laccase producing fungus HC1 was isolated from a sample collected in the Bolivian Amazon region. Analysis of 5.8S and 28S rDNA, and internal transcribed spacer 1 and 2 sequences revealed that isolate HC1 belongs to genus Galerina. High production of laccase was achieved in basal salt medium supplemented with 30 g L-1 glucose, 10 g L-1 yeast extract and 0.01 g L-1 co
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Increasing atmospheric carbon dioxide concentration [CO2] caused by anthropogenic activities has triggered a requirement to predict the future impact of [CO2] on forests. The Hindu Kush Himalayan (HKH) region comprises a vast territory including forests, grasslands, farmlands and wetland ecosystems. In this study, the impacts of climate change and land-use change on forest carbon fluxes and vegeta
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High-frequency in situ measurements at Gosan (Jeju Island, Korea) during November 2007 to December 2008 have been combined with interspecies correlation analysis to estimate national emissions of halogenated compounds (HCs) in East Asia, including the chlorofluorocarbons (CFCs), halons, hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), perfluorocarbons (PFCs), sulfur hexafluoride (SF6),
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Background and Objectives Structural brain MRI and blood-based phosphorylated tau (p-tau) measures are among the least invasive and least expensive Alzheimer's disease (AD) biomarkers to date. The extent to which these biomarkersmay outperformone another in predicting future Alzheimer dementia diagnosis is poorly understood, however. This study investigated 2 specific AD biomarkers, i.e., a cortic
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Oxidative stress plays a crucial role in the development of several liver diseases. Many natural polyphenols can attenuate oxidative stress and liver injury. In this study, a phytochemical profiling of a methanol extract from leaves of Syzygium samarangense revealed 92 compounds belonging to flavonoids, phenolic acids, condensed tannins, and ellagitannins. The S. samarangense extract exhibited a n
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Given the current societal and political developments in Germany, the visibility and integration of-marginalized is essential to ensure their inclusion in mainstream society. One way of encouraging-contact between majority and marginalized groups is through building social networks, of which-informal and nonformal educational activities play an important part. This thesis examines the-experience o
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Torleif Bramryd
Professor emeritus Kontaktinformation E-post: torleif [dot] bramryd [at] ses [dot] lu [dot] se Telefon: +46 42 35 65 65 Mobil: +46 70 393 98 55Organisation Institutionen för tjänstevetenskap WebbplatsTorleif Bramryds profil i Lunds universitets forskningsportalAndra roller Forskare Institutionen för tjänstevetenskap Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera e
https://www.ses.lu.se/torleif-bramryd - 2026-07-24
