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Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c
Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h
https://rwi.lu.se/publications/page/26/ - 2026-07-05
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Objective: To assess the variation in changes in patient-reported outcomes 4 to 6 years after arthroscopic partial meniscectomy (APM).Design:Prospective cohort study.Setting:Orthopedic departments at public hospitals.Patients:Patients (n = 447) from the Knee Arthroscopy Cohort Southern Denmark undergoing APM.Interventions:All patients underwent APM.Main Outcome Measures:Change in KOOS4scores from
Annual and seasonal variations in surface air temperature (SAT) during the period 1961–2011 were analysed using daily mean temperature data sets from regular grid points (10?×?10?km2) throughout Finland. The Mann–Kendall nonparametric test was used to detect significant historical trends in SAT and Spearman's correlation coefficient (?) to test the relationships between SAT patterns and various at
https://www.lusem.lu.se/calendar/food-crime - 2026-07-04
