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Background: Young adults with autism often have problems with body awareness, also acknowledged by physiotherapists. This may interfere with various physiological and psychological responses, expressed in reduced movement quality. Basic Body Awareness Therapy (BBAT) may be suitable to address these difficulties, to enhance body awareness and movement quality to manage everyday life. Body Awareness
BACKGROUND: Individuals with neovascular age-related macular degeneration (AMD) have altered number and distribution of retinal macrophages and show changes in circulating antibodies. We wanted to investigate the corresponding precursors, with subpopulations. We therefore measured monocyte and B-lymphocyte populations in individuals with neovascular AMD.DESIGN: This was an observational case-contr
This explorative literature review aims to examine the content and methodologies of recent empirical studies on the aspirations of youth in situations of migration in Europe. The search yielded 30 peer-reviewed social science publications in English for the period 2010–2022, including both intra-European migrants ages 10–24 and youth with backgrounds from outside Europe. Contextual analysis was us
OBJECTIVE: Determine whether there is a relationship between the number of different lower-limb resistance exercises prescribed in a program and outcomes for people with knee osteoarthritis.METHODS: Systematic review with meta-regression. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and Embase up to 4th January 2024. We included randomised controlled trials th
Myxofibrosarcoma (MFS) and undifferentiated pleomorphic sarcoma (UPS) are two common and aggressive subtypes of soft tissue sarcoma. The aim of this study was to assess potential transcriptomic differences between MFS and UPS tumours and to evaluate the extent to which differences in gene expression profiles were associated with genomic and clinical features. The study included 162 patients with t
Traumatic brain injury (TBI) is a major cause of morbidity and mortality, not least in the elderly. The incidence of aged TBI patients has increased dramatically during the last decades. High age is a highly negative prognostic factor in TBI, and pharmacological treatment options are lacking. We used the controlled cortical impact (CCI) TBI model in 23-month-old male and female mice and analyzed t
Background/aim: Exertional breathlessness is a dominating symptom in cardiorespiratory disease, limiting exercise capacity. Multidimensional measurement has been proposed to capture breathlessness, but it is unknown whether it is useful to differentiate people with abnormal vs normal exertional breathlessness intensity. Methods: This was a secondary analysis of a randomized controlled trial of out
Background and objective The Scania Accelerated Intermittent Theta-burst Implementation Study (SATIS) aimed to investigate the tolerability, preliminary effectiveness, and practical feasibility of an accelerated intermittent theta burst stimulation (aTBS) protocol in treating depression. Methods We used an open-label observational design, recruiting 20 patients (aged 19–84 years) from two public b
Two different food grade functionalised porous calcium carbonates (FCC), with different pore size and pore size distributions, were characterised and used as carrier materials to increase the dissolution rate of poorly soluble flavouring compounds in aqueous solution. The loading level was varied between 1.3% by weight (wt%) and 35 wt%, where the upper limit of 35 wt% was the total maximum loading
Objective: Following the favorable outcomes demonstrated by the Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ENRICH) trial in supratentorial intracerebral hemorrhage (ICH) patients treated with minimally invasive surgery (MIS), and considering the increasing interest in MIS, we aimed to assess the potential eligibility rate for ICH patients in Sweden. Methods: All patients with sp
Background Functional Somatic Disorders (FSD) and Internalizing Psychiatric Disorders (IPD) are frequently comorbid and likely share familial/genetic risk factors. Methods We performed a Common Factor Multivariate Analysis of 2 FSDs, Fibromyalgia (FM) and Irritable Bowel Syndrome (IBS), and two IPDs, Major Depression (MD) and Anxiety Disorders (AD), in five kinds of Swedish female-female relative
BackgroundSymptom severity cutoffs for body dysmorphic disorder (BDD) are lacking, hindering communication between professionals and with the patient community.MethodWe pooled data from 11 clinical trials or high-quality cohort studies from specialist clinics, totaling 804 individuals with BDD (80 % girls/women, 67 % adults). All participants had baseline scores on the adult or adolescent versions
Objective: The aim of this study is to describe how the use of diagnostic imagingfor prostate cancer (PCa) has evolved over time and to determine whether thereare any differences in access to diagnostic imaging, type of cancers detected, andmortality based on the education level of patients.Methods: 11,063 men were recruited between 1991 and 1996 and thenprospectively followed until 2020. All new
Prostate cancer (PCa) incidence has steadily increased in Sweden, more steeply in the mid-1990s caused by increased opportunistic prostate-specific antigen (PSA) testing. Tallness, normal weight, and non-smoking are associated with more PSA testing, which increases detection of low-risk and localised PCa. We investigated time trends of height, body mass index (BMI), and smoking with PCa risk in 17
Objectives Little is known about figure skaters’ mental health. This study aimed to describe anxiety and depression caseness (defined as a screening condition qualifying for psychiatric examination) in competitive figure skaters and analyse factors associated with such caseness.Methods A cross-sectional study was performed in April 2019 among all competitive figure skaters in the south-eastern reg
The aim of this study was to assess the reproducibility of isokinetic and isometric ankle dorsiflexor strength measurements in individuals with post-polio syndrome (PPS). Thirty-one men and women (mean age 63 +/- 7.0 years) with verified PPS, participated in an intra-rater test-retest reproducibility study. Strength of the ankle dorsiflexor muscles in both lower limbs were measured twice, seven da
Objective. We evaluated in a proof-of-concept double-blind placebo-controlled randomized trial the efficacy and safety of intra-articular sprifermin (recombinant human fibroblast growth factor 18) in patients with symptomatic knee OA. Methods. Sprifermin was evaluated as intra-articular injection at 10, 30, and 100μg. Primary efficacy endpoint was change in central medial femorotibial compartment
Aims To explore the prevalence and incidence of paediatric implantable cardioverter-defibrillator (ICD) patients in Sweden and identify risk factors associated with appropriate shocks and adverse events. Methods and results We performed a nationwide, retrospective cohort study of ICD use in paediatric patients (<19 years) between 1995 and 2017; 120 patients underwent ICD implantation at median age
Background: Bile leakage is a severe complication after cholecystectomy and is associated with an increased risk of morbidity and mortality. The aim of this study was to evaluate the incidence of bile leakage post-cholecystectomy and to identify potential risk factors and their association with changes in the incidence of bile leakage over time. Methods: Demographic and perioperative data of all p
Analysis of atrial rhythm is important in the treatment and management of patients with atrial fibrillation. Several algorithms exist for extracting the atrial signal from the electrocardiogram (ECG) in atrial fibrillation, but there are few reports on how well these techniques are able to recover the atrial signal. We assessed and compared three algorithms for extracting the atria] signal from th
