Filtyp
Abstract: Bladder cancer is a heterogenous disease, ranging from minimally invasive, low-grade tumours with lowrecurrence rates and mortality on one end of the spectrum, and muscle invasive, high-grade disease prone torecurrence, progression and death at the other end.The aim of this thesis was to investigate the expression, clinicopathological correlates and prognostic significanceof the candidat
BACKGROUND: Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterised by progressive neurological degeneration, where the rate of neurological disease progression varies depending on age at neurological onset. We report longitudinal data on functional disease progression and safety observations in patients in the international NPC Registry who received continuous treatment w
Background: Dietary risks today constitute the largest proportion of disability-adjusted life years (DALYs) globally and in Sweden. An increasing number of people today consume highly processed foods high in saturated fat, refined sugar and salt and low in dietary fiber, vitamins and minerals. It is important that dietary trends over time are monitored to predict changes in disease risk. Methods:
BACKGROUND: The risk of spinal haematoma in patients receiving epidural catheters is estimated using routine coagulation tests, but guidelines are inconsistent in their recommendations on what to do when results indicate slight hypocoagulation. Postoperative patients are prone to thrombosis, and thromboelastometry has previously shown hypercoagulation in this setting. We aimed to better understand
All animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. One of the most common types of GAGs is chondroitin/dermatan sulfate (CS/DS), where the repeating disaccharide backbone consAll animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. One of the most common types of GAGs is chondroitin/dermatan sulfate (CS/DS), where the repeating disaccharide backbone cons
Sammanfattning Instansordningsprincipen är en förvaltningsrättslig princip som huvudsakligen medför att parterna i ett förvaltningsmål är förhindrade att tillföra nytt processmaterial i högre instanser. Principen är, emellertid, inte uttryckligen lagstadgad i Förvaltningsprocesslagen (1971:291), FPL. Istället är det upp till förvaltningsdomstolarna att tolka de uttalande som finns i förarbetena tiSummary The principle of the court hierachy is a principle within administrative law whose intention is to prevent the parties to add new case material in the higher instances. The principle, however, is not explicitly stated in the Administrative Court Procedure Act (1971: 291), FPL. Instead, the administrative courts are given the task to interpret various statements contained in the legislative
Popular science summary Are drugs only drugs for human being? An experiment to see if some of the anthropogenic pharmaceuticals are toxic contaminants for the aquatic environment. All kinds of pharmaceuticals have been using widely and the amount has been increased significantly during the last few decades. Concerns about the occurrence of pharmaceuticals releasing into different matrixes of th
Syftet med examensarbetet har varit att utveckla och utvärdera ett realtidssystem som utför analys i molnet och lokalt med hjälp av AWS. De viktigaste målen har varit att skapa ett system som är så snabbt som möjligt och att analysera vilken del av analysen som kan göras i molnet och vilken del som måste göras lokalt. Den förväntade nyttan med systemet är de minskade utvecklings- och underhållskosThe purpose of the degree project has been to develop and evaluate a real-time analysis system which performs analysis in the cloud and locally using AWS. The most important goals have been to create a system which is as fast as possible and to reflect over which part of the analysis can be made in the cloud and which part has to be made local. The expected utility of the system is a consequence o
Colorectal cancer (CRC) is one of the most common forms of human cancer worldwide with approximately 1 million new cases detected every year. CEA is currently the only accepted CRC marker incorporated into clinical practice, where it is used for early detection of metastasis in follow-up of patients having stage II and III disease, and for monitoring response to adjuvant treatment. However there a
Konkurrensen inom EU är reglerad genom konkurrensrätten i syfte att skapa och upprätthålla en effektiv marknad, den inre marknadens funktion samt välfärden för konsumenten. Förbudsregeln – se art. 101 FEUF och 2:1 KL – utgör tillsammans ett centralt verktyg som ska användas av kommissionen eller annan konkurrensmyndighet för att bryta upp otillåtna samarbeten mellan två eller fler företag, vilka äCompetition within the European union is regulated through a system of competition rules, with the purpose of creating and maintaining an efficient market, the function of the inner market and the consumer welfare. The prohibition rule – see art. 101 TEUF and 2:1 KL – constitutes together an essential tool that ought to be used to break up unwarranted collaborations between two or more undertaking
ABSTRACT Purpose: The purpose of this study was to explore the current factors affecting fertility preference and fertility behaviour in Shanghai among the first single-child generation who are now entering into their childbearing years. In order to gain a more clear understanding of fertility preference and fertility behaviour in Shanghai the following areas were explored in an attempt to discov
Trots tydlig rättspraxis och en stark politisk vilja att säkra rätten för varje enskild eller företag som lidit skada vid brott mot EU:s konkurrensregler – i synnerhet artiklarna 101 och 102 Fördraget om Europeiska unionens funktionssätt (EUF) - att kunna söka kompensation, så har det konkurrensrättsliga skadeståndet inte fått något större genomslag. Europakommissionen (”Kommissionen”) har med andDespite the clear view of the European Commission (“the Commission”) and the European Court of Justice (“the ECJ”) that any citizen or business suffering harm following a breach of the EU competition rules - in particular Articles 101 and 102 of the Treaty of the Functioning of the European Market (TFEU) - should be able to obtain damages from the infringing party, to this date, damages have only
This master’s thesis explores how a Global Manufacturing Network can be designed with predefined requirements for local final assembly at an overseas plant. This was done in collaboration with Alfa Laval, where the global manufacturing network of Freshwater Generators (FWGs) was analyzed. The study evaluated options of sourcing directly from suppliers and via the main factory to different extents.
Modern society depends on dams for renewable hydropower, water supply, and flood control. As climate change increases the frequency of extreme rainfall and flood events, and as the demand for renewable energy sources continues to grow, ensuring the safety of these critical structures becomes more urgent than ever. One of the most serious hidden threats in embankment dams is internal erosion – a sl
1. To investigate further the release, localization and identity of a non-nitrergic mediator of smooth muscle relaxation in the female pig urethra, we studied the effects of drugs acting at alpha 2-adrenoceptors or K+ channels, the effects of capsaicin and chemical sympathectomy, and the actions of several transmitter candidates. 2. Electrical field stimulation (EFS; frequencies above 12 Hz) of sp
Krediter spelar en central roll i det moderna konsumtionssamhället och möjliggör för konsumenter att finansiera köp som de annars inte skulle ha råd med. Samtidigt medför en överdriven upplåning risker, då konsumenter kan åta sig skulder de inte kan återbetala, vilket kan leda till överskuldsättning. Problemet har både individuella och samhälleliga konsekvenser: individen kan uppleva allvarlig ekoCredit serves as a fundamental pillar of modern consumer-driven economies, empowering individuals to finance substantial purchases that would otherwise be unattainable. However, excessive borrowing carries risks, as consumers may accumulate debts they cannot repay, leading to over-indebtedness. This issue has both personal and societal consequences: individuals may experience severe financial dist
Climate changes have had marked impacts on the natural systems. However its impact will be significant with the hydrological cycle. It is agreed that climate change have adverse impacts on socio-economic development of all nations. But, it is expected that its impact will hit developing countries the worst. The objective of this thesis is to assess the impact of climate change on Gilgel Abay River
Hållbarhetsplan för Lunds universitet 2020–2026 Hållbarhetsplan för Lunds universitet 2020–2026 REVIDERAD 2022 | BESLUTAD AV REKTOR 2023-02-02 DNR STYR 2022/2555 | LUNDS UNIVERSITET FO T O : H Å K A N R Ö JD E R , K E N N E T R U O N A , JO H A N P E R S S O N Innehållsförteckning 1. INLEDNING ................................................................................... 4 1.1 Syfte .........
Centre for Retail Research at Lund University ANNUAL REPORT | 2024 2 ANNUAL REPORT CENTRE FOR RETAIL RESEARCH AT LUND UNIVERSITY 2024 3 ANNUAL REPORT CENTRE FOR RETAIL RESEARCH AT LUND UNIVERSITY 2024 Introduction Centre for Retail Research – 2024 the final chapter This is the 11th annual report from the Centre for Retail Re- search at Lund University. It is also the last we will send. While trans
Previous studies on lymphocytes have suggested that patients with head and neck squamous cell carcinoma (HNSCC) have an increased susceptibility for chromosomal damage induced by bleomycin, a known radiomimetic mutagen. However, it has so far not been possible to study whether this genetic instability is present also in the epithelial component of the upper aerodigestive tract mucosa, the tissue f
