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Objective: To determine the burden of comorbidities in OA and their temporal relationships in the UK. Methods: The Clinical Practice Research Datalink (CPRD) GOLD was used to identify people with incident OA and age, gender and practice matched non-OA controls from UK primary care. Controls were assigned the same index date as matched cases (date of OA diagnosis). Associations between OA and 49 in
Background and objective: There is an unmet need to avoid long-term morbidity associated with standard cytotoxic treatment for low-volume metastatic seminoma. Our aim was to assess the oncological efficacy and surgical safety of retroperitoneal lymph node dissection (RPLND) as treatment in a population-based cohort of metastatic seminoma patients with limited retroperitoneal lymphadenopathy. Metho
Background: Expiratory flow limitation (EFL) during tidal breathing and lung hyperinflation have been identified as major decisive factors for disease status, prognosis and response to therapy in obstructive lung diseases. Aim: To investigate the delta values between expiratory and inspiratory resistance and reactance, measured using respiratory oscillometry and its correlation with air trapping a
Background: Road-traffic noise may influence the development of cardiovascular events such as stroke and myocardial infarction, but etiological mechanisms remain unclear. This study aimed to assess the relationship between long-term road-traffic noise exposure and coronary atherosclerosis in Sweden. Methods: In the Swedish CArdioPulmonary bioImage Study (SCAPIS) cohort, including 30,154 subjects a
BACKGROUNDRecanalization sometimes fails during endovascular thrombectomy due to target vessel access failure. Two‐dimensional/3‐dimensional fusion imaging in the Siemens ARTIS Icono biplane platform may facilitate access by fusing the preoperative computed tomography angiography with procedural imaging. This observational study aimed to evaluate vascular access, success rates, and procedure times
Background. Flecainide is a first-line rhythm control treatment for patients with atrial fibrillation (AF), however long-term treatment outcomes are understudied. Objective. To investigate associations of electro- (ECG) and echocardiographic indices with safety and efficacy outcomes of long-term flecainide treatment for recurrent AF. Methods. Consecutive patients with AF admitted for in-hospital f
During protoplanetary disk formation, dust grains located in the outer disk retain their pristine icy composition, while solids in the inner stellar-heated disk undergo volatile loss. This process may have left a fossil record in Solar System material, showing different nucleosynthetic imprints that have been attributed to different degrees of thermal processing. However, it remains unclear how a
Background: Restricted weight-bearing is still used after lower extremity fracture surgery in elderly patients. The long-term effect on gait recovery in elderly patients with distal femur fractures (DFF) and their ability to comply with the restrictive weight-bearing regime is unknown. This study aimed to investigate the effect of restricted postoperative weight-bearing on gait recovery (actual we
Background and aims: Previous study showed that elevated circulating hepatokine follistatin (FST) associates with an increased risk of type 2 diabetes by inducing adipose tissue insulin resistance. Here we explore further the relationships between plasma FST levels with mortality and health outcomes. Methods and results: The population-based Malmö Diet Cancer cardiovascular cohort (n = 4733, age 4
Inherent errors in tipping bucket flow meters may limit monitoring data reliability. In this work, we perform the static and dynamic calibration of four large tipping buckets, apply different regression curves and investigate the possible measurement error sources. The volumetric capacity (static calibration) of each piece of equipment was determined. They were tested (dynamic calibration) under t
OBJECTIVE: to examine the association between different patterns of impaired lung function with the incident risk of dementia and magnetic resonance imaging (MRI)-based brain structural features. METHODS: in UK Biobank, a total of 308,534 dementia-free participants with valid lung function measures (forced expiratory volume in 1 s [FEV1] and forced vital capacity [FVC]) were included. Association
Groundwater is a crucial source of water supply in drought conditions, and an auxiliary water source in wet seasons. Due to its increasing importance in view of climate change, predicting groundwater level (GWL) needs to be improved to enhance management. We used adaptive neuro-fuzzy inference systems (ANFIS) to predict the GWL of the Urmia aquifer in northwestern Iran under various input scenario
Background: Gallstones affect women more frequently than men, and symptomatic gallstones are increasingly treated with surgical removal of the gallbladder (cholecystectomy). Breast, endometrial, and ovarian cancer share several risk factors with gallstones, including overweight, obesity, and exposure to female sex hormones. We intended to assess the association between chole-cystectomy and female
OBJECTIVE: To assess the progression of type 1 diabetes using time to peak glucose or C-peptide during oral glucose tolerance tests (OGTTs) in autoantibody-positive relatives of people with type 1 diabetes. RESEARCH DESIGN AND METHODS: We examined 2-h OGTTs of participants in the Diabetes Prevention Trial Type 1 (DPT-1) and TrialNet Pathway to Prevention (PTP) studies. We included 706 DPT-1 partic
The clinical evaluation of regional delays in myocardial motion (myocardial asynchrony) has proved problematic, yet it remains an important functional parameter to evaluate. Prior attempts to quantify regional asynergy have met with limited success, often thwarted by the low temporal resolution of imaging-system data acquisition. If a delay in onset of motion of 30-40 msec is clinically important
https://www.solid.lth.se/ - 2026-07-11
Microsoft Word - Medlemmar i Epigenetics.docx Epigenetics: June 2009-‐July 2010 Anders Castor, PhD and MD in Paediatrics, Lund University. With a focus on oncology in children, the function of tumour cells and the factors behind tumour development. Tommy Bengtsson is Professor of Demography and Economic History at Lund University and has specialize
https://www.pi.lu.se/sites/pi.lu.se/files/medlemmar_i_epigenetics.pdf - 2026-07-11
Brevmall STRATEGY 27 November 2014 Reg. no SAMV 2014/176 Vice-Chancel lor Lund University’s strategy for cooperation with Africa Approved by the vice-chancellor on 27 November 2014 A. Summary Lund University wishes to reinforce its cooperation with African universities. Internationalisation is one of the University’s prioritised strategies and increased cooperation with Africa is in line with this
https://www.plog.lth.se/research/ - 2026-07-11
