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Heart transplantations have made it possible to extend the median survival time to 12 years for patients with end-stage heart diseases. This operation is unfortunately limited by the availability of donor organs and patients have to wait on average about 200 days in a waiting list before being operated. This waiting time varies considerably across the patients. In this paper, we studied the outcom

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The development of reliable tissue engineering methods using decellularized cadaveric or donor lungs could potentially provide a new source of lung tissue. The vast majority of current lung decellularization protocols are detergent based and incompletely removed residual detergents may have a deleterious impact on subsequent scaffold recellularization. Detergent removal and quality control measure

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Multidrug resistance (MDR) poses a major obstacle to successful chemotherapeutic treatment of cancer, and often involves multiple genes, which may be regulated post-transcriptionally by microRNAs (miRNAs). The purpose of the present study was therefore to identify any resistance-associated changes in miRNA expression in a sensitive and five increasingly drug-resistant Ehrlich ascites tumor (EAT) c

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This study analyses which perspectives occur in science students’ texts at different points in time during the process of writing a popular science article. The intention is, thus, to explore how popular science writing can help students discover and discuss different perspectives on science matter. For this purpose, texts written by 12 bachelor students in biology were analysed in a case study. Fhis study analyses which perspectives occur in science students’ texts at different points in time during the process of writing a popular science article. The intention is, thus, to explore how popular science writing can help students discover and discuss different perspectives on science matter. For this purpose, texts written by 12 bachelor students in biology were analysed in a case study. Fo

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Manipulation of specific binding and recycling of materials are two important aspects for practical applications of molecularly imprinted polymers. In this work, we developed a new approach to control the dynamic assembly of molecularly imprinted nanoparticles by surface functionalization. Molecularly imprinted polymer nanoparticles with a well-controlled core-shell structure were synthesized usin

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An explicit expression, free from adjustable parameters, is derived for the effective pair interaction between charged colloidal spheres at high concentration in a medium containing an electrolyte. This is accomplished by first considering the electrostatic interaction between two infinite charged plates placed in a stack of identical plates. These act as a reservoir defining the chemical potentia

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Background: Monitoring the quality of clinical learning environments (CLEs) is immensely important in medical education. Objective indicators of the quality of the CLE can be used to measure learner perceptions and to inform educational improvements; however, many established tools were not designed for use in clinical settings and are not theoretically grounded. Our aim was to apply a new tool to

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The study of localized deformation in porous sandstones at the laboratory scale can yield valuable insights into the internal structures and mechanisms of shear zones and compaction bands that might impact on flow at a reservoir scale. Herein, we report results of a laboratory study of shear and compaction band formation in a porous sandstone using a range of full-field experimental techniques: ac

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Two recent dynamic friction models, the LuGre model and a model by Bliman and Sorine, are investigated and compared. Comparisons are made of captured friction phenomena, behaviour at zero crossings of the velocity and computational issues. Limit cycles in position control of a simple servo with dynamic friction are investigated by means of single input describing function analysis. Both models giv

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The nuclear physics facility at MAX-lab requires high energy electrons for photonuclear experiments. These electrons are first accelerated in two LINACs that are fed via a SLED system. Arcing in the waveguide structures is currently the limiting factor of the available electron energy. In this report, the implementation of a phase modulation scheme into the injector system is presented. This makes

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A summation rule valid for a large class of linear and reciprocal antennas is presented in terms of the electric and magnetic polarizability dyadics. The identity is based on the holomorphic properties of the forward scattering dyadic and includes arbitrary shaped antennas modeled by linear and time-translational invariant constitutive relations. In particular, a priori estimates on the partial re

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For a multiple input multiple output system, antenna selection reduces complexity at the expense of performance. In this paper, we propose two novel RF pre-processing architectures that significantly improve the performance of antenna selection, while marginally increasing the complexity. These architectures introduce an RF pre-processing matrix, M, that multiplies the vector of incoming signals p

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To increase their computational efficiency, time-stepping methods for the solution of ODEs and DAEs are usually adaptive. A control system for the adaptivity includes the automatic control of step size as well as method order, and can be constructed using proven design principles from control theory. It is a ''superstructure,'' surrounding the basic method, that manages the computational process.

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High-resolution core-level photoemission is used to study structural aspects for the molecular adsorption of CO on the Rh(111) single-crystal surface, and in particular to derive the adsorption sites. The site sensitivity of the core-level binding energy and the fact that the core level photoemission signal is proportional to the adsorbate coverage make it possible to study quantitatively how the

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Cartilage proteoglycans were measured, by the use of an enzyme-linked immunosorbent assay, in synovial fluids obtained from 109 unselected patients attending an outpatient rheumatology clinic because of inflammation of the knee. The content of proteoglycans in synovial fluid was inversely related to the degree of joint destruction shown on X-ray. The proteoglycan concentrations in knee-joint exuda

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The research in this article examines audience responses to a range of factual and reality genres. It takes as a starting point that television audiences do not experience news or documentary or reality TV in isolation but as part of a range of factual and reality programmes. Factual and reality programming includes a broad understanding of non-fictional programming on broadcast television, satell

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Robustly testing hypotheses of geographic synchroneity of abrupt and extreme change during the late Pleistocene (60,000 to 11,650 years ago) requires a level of chronological precision often lacking in ice, marine and terrestrial sequences. Here we report a bidecadally-resolved New Zealand kauri (Agathis australis) tree-ring sequence spanning two millennia that preserves a record of atmospheric ra

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We present the WD2014 chronology for the upper part (0-2850 m; 31.2 ka BP) of the West Antarctic Ice Sheet (WAIS) Divide (WD) ice core. The chronology is based on counting of annual layers observed in the chemical, dust and electrical conductivity records. These layers are caused by seasonal changes in the source, transport, and deposition of aerosols. The measurements were interpreted manually an