Filtyp
Background: We aimed to investigate the diagnostic performance of S100 as an outcome predictor after out-of-hospital cardiac arrest (OHCA) and the potential influence of two target temperatures (33 °C and 36 °C) on serum levels of S100. Methods: This is a substudy of the Target Temperature Management after Out-of-Hospital Cardiac Arrest (TTM) trial. Serum levels of S100 were measured a posteriori
Denna avhandling studerar faktorer som påverkar rekryterare då de skall välja bland jobbsökande med olika etnisk bakgrund. Generellt förväntades att de sökandes etnicitet skulle påverka rekryterares val och deras uppfattning om vad som är viktigt att ta fasta på hos en arbetssökande person, och att detta kan ske i olika faser av rekryteringsprocessen.Studie 1 visade att företagsnormer påverkar rekThe present thesis aimed to study different factors influencing recruiters when recruiting from an applicant pool with applicants from an ethnic ingroup and outgroup. Ethnicity was predicted to influence recruiters’ perception and behaviour in different phases during recruitment. Study I demonstrated that company norms affect recruiters’ perception of what an employee should be like. Company norms
Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-year period. Methods: Patients with follow-up and tumor samples, treated between 1990 and 2010, in 93 centers/9 countries. Samples w
Alzheimer's disease researchers have been intrigued by the selective regional vulnerability of the brain to amyloid-β plaques and tau neurofibrillary tangles. Post-mortem studies indicate that in ageing and Alzheimer's disease tau tangles deposit early in the transentorhinal cortex, a region located in the anterior-temporal lobe that is critical for object memory. In contrast, amyloid-β pathology
In order to identify the signal epitopes of the neuropeptide Y (NPY) molecule, the conformation of the NPY molecule was pertubated by a systematic double D-amino acid replacement of neighbouring residues. These NPY-analogs were examined for receptor affinity and on biological activity. The rat cerebral cortex and hippocampus were used for binding characteristics on Y1 and Y2 binding sites, respect
Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence suggests that CRC should be considered a heterogeneous disease, with multiple differences between proximal and distal tumours. The immune system may, depending on the context, promote or inhibit tumour growth, and different immune cell subsets have been found to be associated with impaired or improved prognosis
Abstract Noroviruses are now the leading cause of gastroenteritis worldwide. Noroviruses are effectively transmitted due to a low infectious dose, viral shedding in high concentrations, environmental stability, and they induce only a limited immunity after infection. Especially, the norovirus variants of genotype II.4 (GII.4) have seemed greatly adapted for pandemic spread. The high infectivity o
Background: Screening that includes digital breast tomosynthesis (DBT) with two-dimensional (2D) synthetic mammography (SM) or standard 2D digital mammography (DM) results in detection of more breast cancers than does screening with DM alone. A decrease in interval breast cancer rates is anticipated but is not reported. Purpose: To compare rates and characteristics of (a) interval breast cancer in
Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. Genetic aberrations in the mitogen-activating protein kinase (MAPK) pathway are important in melanoma, of which mutations in BRAF and NRAS are the most common. Additionally, recu
OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality
Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied
Importance: This follow-up study of extremely preterm (EPT) children (<27 weeks' gestational age [GA] at birth) revealed major eye and visual problems in 37.9% (147 of 388) of all EPT infants and in 55.4% (67 of 121) of the most immature subgroups at 6.5 years of age. These major eye and visual problems were strongly associated with treatment-requiring retinopathy of prematurity (ROP).Objectives:
Scan2LiU-Dok LINKÖPINGS UNIVERSITET AVTAL 20130619 Avtal om flexibel arbetstid 1 § Bemyndigande Avtalet sluts med stöd av VillkorsavtalNillkorsavtal-T, 4 kap 13 §. 2 § Tillämpningsområde Dnr LiU 2013-00910 För andra arbetstagare vid Linköpings universitet än lärare tillämpas flexibel arbetstid. Med hänsyn till att tjänstgöringen måste anpassas till arbetets krav kan arbetsgivaren dock besluta att
SUS A02 eng 1. Course Details 1. Course code SUS A02 2. Course title: Introductory Course in Swedish for Exchange Students 2. 3. Cycle: X 4. Higher education credits 3 5. Details of approval of course Syllabus approved by the Syllabus Committee of the Faculty of the Humanities and Theology 17th June 2008. 6. Details of changes approved 2. General Information 1. Field(s) (if applicable) 2. Subject
https://www.sol.lu.se/media/utbildning/dokument/kursplaner/SUSA02_eng.pdf - 2026-07-07
Osteoarthritis is a multifactorial degenerative disease characterized by the breakdown of articular cartilage (AC), affecting hundreds of millions of people worldwide. Among many treatment options, hydrogels have emerged as promising candidates for cartilage replacement, due to their structural resemblance to the native tissue. Hydrogels can be made from various materials, and this study focuses o
I och med elektrifieringen av energisektorn ställs höga krav på ökad inhemsk produktion av elektricitet i Sverige. På grund av den nuvarande fördelningen, där en stor del av produktionen sker i norra Sverige medan konsumtionen är koncentrerad till södra delarna av landet, är behovet extra stort i elområde 4 (SE4). Ett län som möter extra stora utmaningar är Skåne där självförsörjningsgraden för elThe current electrification of the energy sector puts high demands on increasing domestic electricity production in Sweden. This issue is enhanced by the current regional imbalance between supply and demand, while a major share of electricity generation is located in northern Sweden, consumption is concentrated in the south. Consequently, the need for new production is particularly great in electr
33Background: PSMA PET has been shown to detect more metastasis and alter management at biochemical recurrence (BCR), but it remains to be determined that it changes oncologic outcome. We assessed the quantitative parameters on 18F-DCFPyL PET at BCR and evaluated their association with tumor volume, metastatic locations with the subsequent biochemical progression free survival (bPFS). Methods: Thi
