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Number theory is in a sense among the oldest disciplines of mathematics. A running theme is that many number theoretic problems are very easy to state and understand. However, actually solving these problems often requires much work or some very clever trick. An extreme case of this would be Fermat's last theorem: originally a conjecture by French lawyer Pierre de Fermat whose statement is und
The work presented in this thesis aims at improving spectroscopic techniques for analysis of pharmaceutical solids. This improvement is achieved by the combining and development of instrumentations and data evaluation tools from two research fields: the fields of near infrared spectroscopy and biomedical optics. The thesis include the construction and evaluation of different variable selection te
Gm allotypes are genetic variants of the immunoglobulin heavy G chains (IGHG) of IgG molecules, coded from chromosome 14q32, characterized by differences in amino acid epitopes of the constant heavy G chains and inherited in the Mendelian manner. Gm allotypes have influence on IgG subclass levels, and serum Gm allotype levels have been given for different Gm genotypes in adults. Four hundred and t
Den svenska stiftelsen är av mycket gammalt ursprung, och idag ryms flera vitt skilda stiftelsetyper inom stiftelsebegreppet. Bland dessa utmärker sig den näringsdrivande stiftelsen. Trots att stiftelsen inte är en association kan den bedriva näringsverksamhet, antingen direkt genom stiftelsen, eller indirekt via näringsdrivande dotterbolag. Under det senaste halvseklet har den näringsdrivande stiThe Swedish foundation (Sw: stiftelse) is of old origin, and today the concept comprises several different types of foundations, among which the enterprise foundation stands out. Though the foundation is not a form of business entity, it can still carry out commercial activities, either directly through the foundation in its own name, or indirectly via subsidiary companies. During the last half-ce
This thesis examines the independence of the UN treaty bodies, both in its entirety and the autonomy of the individual treaty body members. Since independence is very difficult to measure empirically, this paper uses the theoretical framework of Principal-Trustee theory as a tool by which the independence can be understood. This instrument allows us to examine the independence of the treaty body s
Samhället genomgick under 1900-talet stora förändringar. Välfärdsstatens socialpolitiska reformer gjorde att familjens roll förändrades – allt fler av de funktioner som tidigare var förbehållna familjen kom nu att övertas av samhället. Kvinnans ekonomiska självständighet och jämställdhet med mannen stärktes. Kvinnor blev också i allt större utsträckning verksamma på arbetsmarknaden. SkilsmässotaleThe society has experienced major changes in the 20th century. The social politics of the Swedish welfare state has impacted the family role. Important functions which were earlier carried out within the family, is now provided by the social welfare system. The economical independency of the spouses and gender equality strengthened during this period. An additional important factor for the reforma
För att en person ska kunna dömas för ett brott krävs det att denna har handlat med uppsåt eller i vissa fall oaktsamhet. För att uppsåt ska föreligga ska handlingen ha varit medveten och det ska finnas ett kausalsamband mellan denna och dess följd. Uppsåtsbegreppet är indelat i tre grader: avsiktsuppsåt, insiktsuppsåt och likgiltighetsuppsåt och de är graderade i den ordning de räknades upp med dResearchers who studied alcohol dependence in humans have come to the conclusion that alcoholism affects the brain's neurotransmitters, which means that the brain can begin to function differently about exposing the large amounts of alcohol over a long period of time. An addiction to alcohol is hard to recover from, with many severe withdrawal symptoms as a result. In the current legal situati
Anaerobic digestion is a microbially mediated process occurring in nature in the absence of oxygen and other non-carbonaceous electron acceptors. The majority of the carbon of the organic matter degraded in the process is transformed into carbon dioxide and methane. Most of the energy potential of the degraded material is conserved in the methane, thus providing a renewable energy carrier, which c
Popular Abstract in Swedish Nu levande fåglar delas traditionellt in i två grupper. Den ena gruppen är Palaeognathae och omfattar ratiter (struts, nandu etc.) och stubbstjärthöns. Den andra gruppen, Neognathae, representerar alla övriga fåglar, drygt 20 ordningar med över 9.000 arter. Grunden för denna uppdelning utgörs i första hand av morfologiska studier av fåglarnas gommar. Man har ansett att The Class Aves (birds) is generally divided into two main groups - the Palaeognathae and the Neognathae. Paleognathous birds are the flightless ratites and the tinamous, while Neognathae include all other extant birds (more than 9,000 species). This opinion has prevailed for more than a century and is primarily based on morphological studies of the avian bony palate. In this study, the relationsh
Popular Abstract in Swedish Allmän Introduktion Hormonkänsligt lipas (HKL/HSL) är det protein (enzym) som hydrolyserar (bryter ner) det fett som finns lagrat inne i fettcellerna i fettväven. HSL finns också i steroidproducerande vävnader, som t.ex. binjure, äggstockar, moderkaka och testikel, och har troligtvis en viktig funktion i steroidsyntesen i åtminstone vissa av dessa vävnader. Det är dock Hormone-sensitive lipase (HSL) is a key enzyme in adipose tissue that hydrolyses stored fat (triacylglycerol). The activity of HSL is under strict hormonal and neural control. Lipolytic agents, such as catecholamines, increase the cAMP levels, resulting in an activation of cAMP-dependent protein kinase (PKA), which in turn phosphorylates and activates HSL. This thesis describes the structural orga
Popular Abstract in Swedish Ben, brosk och mjukvävnad (utgörs av den tvärstrimmiga muskulaturen, fettväv och fibrös bindväv, men också av det perifera nervsystemet) är vävnader av mesenkymalt eller neuroektodermalt ursprung. De flesta tumörer som uppstår i dessa vävnader är godartade och blir därför ofta inte föremål för behandling, vilket gör det svårt att uppskatta incidensen i befolkningen. EnlBone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. Although many BSTT are rare, it has become clear that BSTT are characterized by recurrent acquired chromosomal aberrations, and the general aim of this thesis have been to apply molecular genetic and molecular cytogenetic techniques to further characterize recurrent breakpoin
Background Acute pyelonephritis is a common infection in adult women, but there is a paucity of controlled trials of its treatment and the optimum duration of antibiotic treatment has not been properly defined. We compared the efficacy of ciprofloxacin for 7 days and 14 days in women with community-acquired acute pyelonephritis. Methods In a prospective, non-inferiority trial undertaken at 21 cent
The monograph reports a number of studies of a therapist’s speech. It comprises three chapters. The first chapter is a theoretical introduction into the scientific problem of the psychotherapeutic utterance. It reveals some psychological aspects of language issue, explains the concepts of “utterance” and “psychotherapeutic utterance”, and provides an account of the research methods used for studyi
Introduction: Few studies have investigated overall satisfaction with prostheses fabricated using low-cost technology. Evidence-based recommendations for prosthetic and orthotic services in low-income countries are needed in order to more effectively provide services. Detailed analysis of variables which influence patient satisfaction with assistive devices are therefore of interest to investigate
Context. Elements heavier than iron are produced through neutron-capture processes in the different phases of stellar evolution. Asymptotic giant branch (AGB) stars are believed to be mainly responsible for elements that form through the slow neutron-capture process, while the elements created in the rapid neutron-capture process have production sites that are less understood. Knowledge of abundan
Nasonia vitripennis is an emerging insect model system with haplodiploid genetics. It holds a key position within the insect phylogeny for comparative, evolutionary and behavioral genetic studies. The draft genomes for N. vitripennis and two sibling species were published in 2010, yet a considerable amount of transcriptiome data have since been produced thereby enabling improvements to the origina
We know now that discs of gas and dust, so-called protoplanetary discs, form planets as side-products of the naturally occurring star formation process throughout the Milky Way. Young, growing planets in such discs are commonly referred to as protoplanets. In about 10\% of the so-far observed stars, this planet formation process leads to the occurrence of giant planets, such as Saturn, Jupiter, or
Languages borrow words when there is a need for it, all languages contain loanwords, and no part of the lexicon is entirely “loan-proof”. These are statements about lexical borrowing that are typically found in linguistic textbooks (Hock and Joseph 1996). Further, we know that that there are large discrepancies in the borrowability of different lexical concepts, where core vocabulary domains (sens
OBJECTIVE: To investigate the effect of the epidermal growth factor receptor (EGFR) on the induction of apoptosis by the chemotherapeutic agent etoposide (VP16), and to examine the effect of combining VP16 with gefitinib to see if the cell-survival mechanism can be prevented.MATERIALS AND METHODS: The bladder cancer cell lines RT4 and T24, representing low- and high-malignancy grades respectively,
Nanowire (NW) based devices provide bright possibilities for many different applications [1]. The use of block copolymers (BCPs) for nanopatterning of dielectric masks for selective area metal-organic vapor phase epitaxy (MOVPE) of III-V nanowires [2] and for NW-device applications [3] has a great potential, when it comes to increasing the NW density and reducing their diameters, which is importan
