Filtyp
CCND1 amplification results in cyclin D1 overexpression. However, other unidentified genetic mechanisms contribute to enhanced gene expression. In the present study, 32 squamous cell carcinoma of the head and neck (SCCHN) were investigated regarding chromosomal abnormalities involving 11q13 by cytogenetic analysis, genomic CCND1 amplification by differential PCR and FISH, and cyclin D1 expression
Background: A study was undertaken to investigate the sociodemographic distribution of workplace exposure to environmental tobacco smoke (ETS) in a Swedish working population sample. Methods: 8,270 individuals were assessed by questionnaire in the Scania Public Health Survey. The influence of sociodemographic factors on ETS exposure at work was investigated by multivariable regression analysis. Re
The purpose of the present study was to establish a rapid and reproducible method for quantification of tissue-infiltrating leukocytes using computerized image analysis. To achieve this, the staining procedure, the image acquisition, and the image analysis method were optimized. Because of the adaptive features of the human eye, computerized image analysis is more sensitive to variations in staini
The purpose of this study was to investigate the prognostic implications of BCL6 rearrangement in a uniformly treated population of patients with diffuse large B-cell lymphoma (DLBCL) and to characterise the relationship between BCL6 rearrangement and prognostic factors. A total of 269 patients with DLBCL entered a randomised trial comparing the chemotherapy regimen CHOP (cyclophosphamide, doxorub
Popular Abstract in Swedish I den här doktorsavhandlingen presenteras ett datorprogram som utvecklats för att simulera och utvärdera biotekniska processer, där flera processteg kan vara integrerade. Speciellt har en process för framställning av mjölksyra från vetemjöl studerats. Mjölksyra har traditionellt använts i kemi-, läkemedels- och livsmedelsindustrin som t.ex. råvara, surgörare eller konseBiotechnical processes are often integrated to increase productivity and yield. It is difficult to predict the effects of process integration and to find optimum conditions for the process. A valuable tool for the evaluation of a complete process is mathematical modelling. In this thesis, a computer program developed for simulation and optimisation of integrated biotechnical processes is presented
This paper addresses variations in the wind climate in relation to changes in the impact of wind erosion on agricultural lands with Scania, the southernmost province of Sweden, as an example. The literature concerning wind erosion in the region is reviewed and the conclusions are linked to recent analyses of the regional wind climate. Presently, wind erosion occasionally induces problems in light
Objective To explore fetal ductus venosus (DV) flow velocity changes relative to umbilical artery (UA) blood flow and brain-sparing flow (BSF) during uterine contractions. Methods Forty-five term fetuses suspected of having growth restriction were exposed to an oxytocin challenge test (OCT) with simultaneous Doppler velocimetry in the UA, middle cerebral artery (MCA) and DV. Basal BSF was defined
Abstract in German 62 anti-HCV und HCV-RNA-positive schwedische Blutspender (44 Männer, 18 Frauen, Alter im Median 34 Jahre) wurden untersucht. Die HCV-Genotypen wurden in Korrelation gesetzt zu parenteralen Risikofaktoren, Lebermorphologie, Serum-Alanin-Aminotransferase (ALAT)-Spiegeln und HCV-Antikörperprofil. 40% der Spender waren mit dem HCV-Genotyp 1a infiziert, 10% mit 1b, 21% mit 2b und 29%Sixty-two anti-HCV and HCV-RNA positive Swedish blood donors (44 men, 18 women; median age 34 years) were studied. HCV genotypes were correlated to parenteral risk factors, liver morphology, serum alanine aminotransferase (ALAT) levels and HCV antibody profile. Forty percent of the donors were infected with HCV genotype 1a, 10% with 1b, 21% with 2b, and 29% with 3a. Intravenous drug use (IVDU) was
Although the systemic changes towards innovation networking between university-industry and governmental actors have recently found a place on the international policy and literature agenda, networking between the organizations and people - for the national survival, production and growth - has been deeply rooted in the Israeli system even before the establishment of the Israeli State in 1948. Int
Popular Abstract in Swedish Denna avhandling i socialantropologi ägnas åt analysen av sociala och kulturella processer i Visaginassamhället efter sovjettiden. Visaginas (tidigare Sniechkus) byggdes under sovjettiden, åren 1975-1989, som hemvist för personal vid Ignalinas kärnkraftverk och deras familjer. De flesta invånarna i staden är ryssar som kom till Litauen mellan 1975 och 1989 för att byggaThis thesis focused on an examination of human agency and strategies for responding to rapid social and economic change. Fieldwork was carried out in the community of Visaginas town that was built during the Soviet period in Lithuania. The town is situated next to the Ignalina nuclear power plant. The majority of the town's inhabitants are Russians who immigrated to Lithuania from other areas of t
The affinity and enantioselectivity have been determined for designed propranolol derivatives as ligands for Cel7A by capillary electrophoresis (CE) at pH 7.0. These results have been compared to measurements at pH 5.0. In agreement with previous studies, the affinity increased at the higher pH. However, the affinity was not as dependent of the ligand structure at pH 7.0 as at pH 5.0, and the sele
OBJECTIVE: To determine the prevalence of focally growing lesions in the uterine cavity in women with postmenopausal bleeding and endometrium > or = 5 mm and the extent to which such lesions can be correctly diagnosed by D&C. METHODS: In a prospective study, 105 women with postmenopausal bleeding and endometrium > or = 5 mm at transvaginal ultrasound examination underwent diagnostic hysterosco
The aim of this study was to investigate whether there is an association between overexpression of cyclin D1 and response to therapy. Immunohistochemical overexpression of cyclin D1 was determined in paraffin-embedded specimens from diagnostic biopsies of 89 primary cases of squamous cell carcinoma of the head and neck (SCCHN), using a polyclonal antiserum. The tumor response rates were estimated
Abstarct is not available
In this article, the author discusses the implications of a 6+6-hour model for the production economy of the Finnish Company Essilor Oy. The theory of returns to scale has been used to analyse the results of the change from one 8-hour shift to the 6+6-hour-shift system. It is shown that the company Essilor attained a better production economy and increased profit by introducing a 6+6-hour-shift sy
This paper considers the potential contribution of Industrial Symbiosis (IS) networks in fostering environmental innovation at the local or regional level. Drawing on literature from innovation studies and innovation in spatial proximity, we outline three factors that are important for the innovation process and identify where the effects from IS networks can be explored. We use observations from
