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Strategies for formaldehyde detection in flames and engines using a single-mode Nd:YAG/OPO laser system

This paper presents technical developments for the detection of formaldehyde (CH2O) using laser-induced fluorescence. The easily accessible third harmonic of the Nd:YAG laser at 355 nm was used for excitation of formaldehyde. In order to investigate potential background fluorescence, e.g., from large molecules such as polyaromatic hydrocarbons, special attention was paid to investigating the possi

Impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in patients with severe asthma

Background: There is little agreement on clinically useful criteria for identifying real-world responders to biologic treatments for asthma. Objective: To investigate the impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in adults with severe asthma. Methods: This was a longitudinal, cohort study across 22 countries participating in the International Sever

Systems biology analysis of human genomes points to key pathways conferring spina bifida risk

Spina bifida (SB) is a debilitating birth defect caused by multiple gene and environment interactions. Though SB shows non-Mendelian inheritance, genetic factors contribute to an estimated 70% of cases. Nevertheless, identifying human mutations conferring SB risk is challenging due to its relative rarity, genetic heterogeneity, incomplete penetrance, and environmental influences that hamper genome

Combinatorial inkjet printing for compositional tuning of metal-halide perovskite thin films

To accelerate the materials discovery and development process for a sustainable technology advancement it is imperative to explore and develop combined high-throughput material synthesis and analysis workflows. In this work, we investigate a method of combinatorial inkjet-printing to tune the composition of the inorganic cesium lead mixed halide perovskite solid solution, CsPb(BrxI1-x)3. The compo

Field-hybridization acoustic tweezers

Precise control of individual particles is crucial for biomedical diagnostics, i.e., single-cell analysis and drug delivery. Acoustic tweezers have shown promise as a precise method for capturing microscale objects, but the spatial selectivity remains challenging to achieve with traditional electroacoustic transducers. An alternative to traditional ultrasound generation is to use photoacoustic con

Molecular imprinting: Synthetic materials as substitutes for biological antibodies and receptors

Molecular imprinting is a versatile technique providing functional materials able to recognize and in some cases respond to biological and chemical agents of interest. In contrast to biological antibodies, the best known receptors derived from biological combinatorial processes, molecularly imprinted polymers (MIPs) are obtained by template-directed synthesis. Thus, molecular imprinting can more p

The influence of parasitic modes on beam dynamics for the European spallation source linac

The European Spallation Source (ESS) linac will consist of three families of superconducting RE cavities to accelerate protons to a final beam energy of 2.5 GeV for collision with the target. Beam induced HOMs in these cavities may drive the beam unstable and increase the cryogenic load, severely limiting the operation of the linac. The effect of these modes on the beam quality is investigated in

Narrow journal bearings

In this report, numerical analyses of very narrow journal bearings are presented. The pressure distribution was determined for a number of different width-diameter ratios and eccentricities. For each combination, a number of relevant dimensionless design quantities were computed. The next step was to obtain curve-fitted functions for the variation in each design quantity. The functions are intende

A method for linking safety factor to the target probability of failure in fire safety engineering

Ensuring occupants' safety in building fires is one of the most important aspects for fire safety engineering. Many uncertainties are inevitably introduced when estimating the occupant safety level, due to the high complexity of fire dynamics and the human behaviour in fires. Safety factor methods are traditionally employed to deal with such uncertainties. This kind of methods is easy to apply but

Constraining general two Higgs doublet models by the evolution of Yukawa couplings

We study how general two Higgs doublet models can be constrained by considering their properties under renormalization group evolution of the Yukawa couplings. We take into account both the appearance of a Landau pole as well as off-diagonal Yukawa couplings leading to flavour changing neutral currents in violation with experimental constraints at the electroweak scale. We find that the latter con

Cellulose Dissolution in an Alkali Based Solvent: Influence of Additives and Pretreatments

The distinction between thermodynamic and kinetics in cellulose dissolution is seldom considered in the literature. Therefore, herein an attempt to discuss this topic and illustrate our hypotheses on the basis of simple experiments was made. It is well-known that cellulose can be dissolved in a aqueous sodium hydroxide (NaOH/H2O) solvent at low temperature but it is here shown that such an alkalin

Development and evaluation of a computer-based educational program for adults with congenitally malformed hearts

Background: There is a lack o educational material for adults with congenitally malformed hearts. Computer-based education has shown to have significant effects on knowledge and management of chronic diseases. Aim: The aim of this study was to develop and evaluate a computer-based educational program for adults with congenitally malformed hearts. Methods: The program was developed by a multidiscip

Dynamical systems and commutants in crossed products

In this paper, we describe the commutant of an arbitrary subalgebra A of the algebra of functions on a set X in a crossed product of A with the integers, where the latter act on A by a composition automorphism defined via a bijection of X. The resulting conditions which are necessary and sufficient for A to be maximal abelian in the crossed product are subsequently applied to situations where thes

Automatic Analysis and Reduction of Reaction Mechanisms for Complex Fuel Combustion

This work concentrates on automatic procedures for simplifying chemical models for realistic fuels using skeletal mechanism construction and Quasi Steady-State Approximation (QSSA) applied to detailed reaction mechanisms. To automate the selection of species for removal or approximation, different indices for species ranking have thus been proposed. Reaction flow rates are combined with sensitivit