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Recent advances in MRI and increasing knowledge on the characterization and anatomical variability of medial temporal lobe (MTL) anatomy have paved the way for more specific subdivisions of the MTL in humans. In addition, recent studies suggest that early changes in many neurodegenerative and neuropsychiatric diseases are better detected in smaller subregions of the MTL rather than with whole stru
OBJECTIVES: It has been commonly accepted that untreated acute type A aortic dissection (ATAAD) results in an hourly mortality rate of 1–2% during the 1st 24 h after symptom onset. The data to support this statement rely solely on patients who have been denied surgical treatment after reaching surgical centres. The objective was to perform a total review of non-surgically treated (NST) ATAAD and p
Background: There are currently no molecular tests to identify individual breast cancers where radiotherapy (RT) offers no benefit. Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) is a 16-gene molecular signature developed to identify low-risk cancers where RT will not further reduce recurrence rates. Methods: An individual participant data meta-analysis was performed in 623 patien
Title: Knowledge acquisition for a new business model creation and enabling factors Date of the seminar: 28-05-2015 Course: Master Corporate Entrepreneurship and Innovation Internship and Degree Project (Master Thesis 15 ECTS) Authors: Dovilė Gedvilaitė and Shubhabrata Paul Supervisor: Dr. Joakim Winborg Keywords: business model innovation, change, creation, knowledge, knowledge acquisition
This essay focuses on the increasing problems for companies and right-holders with counterfeited and pirated goods in the European Union and the problems for right holders to enforce their IPR rights. Will IPRED1 make a difference and is there really a need for the new Directive of Enforcement 2004/48/EG, or do the sanctions according to the TRIPS Agreement suffice. Further, IPRED2 is a follow up
Personer med nedsatt beslutsförmåga kan till följd av kognitiva nedsättningar inte alltid samtycka till vård. Eftersom det inte finns någon specialanpassad lag för denna patientgrupp har det under flera års tid varit svårt att tillämpa regelverken inom hälso- och sjukvården. Det har tillsatts ett flertal kommittéer för att undersöka möjligheterna att stifta ett anpassat regelverk. Detsamma gäller People with reduced decision-making capacity can not always consent to care as a result of cognitive impairments. Because no specially adapted law for this patient group exists, it is difficult to applicate the current legal framework within the Swedish health care system when caring for such individuals. A number of committees have been appointed to examine the possibilities of establishing an ad
This paper examines social policy in the European Union with a specific focus on parental leave, in-cluding earmarked paternity leave. It traces the process of how the legislation of parental leave has gone through a process of Europeanization and through the decision-making process of the European Union, resulted in the Directive 2019/1158. Moreover, it aims at examining the Danish knowledge of t
This master’s thesis is a qualitative content analysis of nine municipal library plans (and two county library plans) with a basis in new institutionalism, specifically in regards to legitimacy, homogeneity as well as themes and patterns in the sourcematerial. With a basis in the history of the library plan and the municipal gouvernance, debate in regards to cultural policy, the downsizing of libr
This study investigated how individuals combine information learned across temporally separate events in order to make novel inferences through memory integration, utilising EEG to provide a novel investigation with high temporal resolution. Participants completed an associative inference task (Zeithamova & Preston, 2010) modified for EEG across three experiments, during which they learned st
AIM: Acute kidney injury (AKI) is a common complication of medical and surgical interventions in hospitalized patients and associates with high mortality. Our aim was to examine renal recovery and long-term survival and time trends in AKI survival.METHODS: Changes in serum creatinine (SCr) were used to define AKI in patients at Landspitali University Hospital in Iceland from 1993 to 2013. Renal re
AimsAtrial septal defects (ASDs) lead to volume-loaded right ventricles (RVs). ASD closure does not always alleviate symptoms or improve exercise capacity, which is possibly explained by impaired left ventricular (LV) haemodynamics. This study evaluated the effect of ASD closure in children using non-invasive LV pressure–volume (PV) loops derived from cardiac magnetic resonance (CMR) imaging and b
OBJECTIVES: To identify multimorbidity trajectories over 20 years among incident osteoarthritis (OA) individuals and OA-free matched references.METHODS: Cohort study using prospectively collected healthcare data from the Skåne region, Sweden (~1.4 million residents). We extracted diagnoses for OA and 67 common chronic conditions. We included individuals aged 40+ years on 31 December 2007, with inc
In the context of biomedical researchinvolving human subjects, the reviewof research proposals by ethics committeesin virtually every country hastraditionally focused on informed consentand other protections for individualsparticipating in research (1). However,the substantial societal implications ofmodern biomedical research and the globalizationof scientific inquiry make it importantto understa
Background: Women with intellectual disability (ID) may encounter barriers to exercising reproductive agency, self-care during pregnancy, and accessing healthcare to optimize pregnancy outcomes. However, there is to date little evidence to guide policy and practice. We aim to fill this identified knowledge gap by examining pregnancy outcomes among women with ID in comparison with women from the ge
Gait Speed Reserve (GSR) expresses a difference between fast and comfortable gait speed and may have an impact on everyday functioning. It was also hypothesized as a useful proxy measure of physiological reserve. However, height-normalizing values of GSR and its associated factors have not been evaluated in a general population of older adults. Therefore, we aimed to investigate the distribution o
