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Background: There are currently no molecular tests to identify individual breast cancers where radiotherapy (RT) offers no benefit. Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) is a 16-gene molecular signature developed to identify low-risk cancers where RT will not further reduce recurrence rates. Methods: An individual participant data meta-analysis was performed in 623 patien
In-situ, quasi-continuous measurements of atmospheric hydrogen (H-2) have been performed since October 2007 at the Cabauw tall tower station in the Netherlands. Mole fractions of H-2, CO and several greenhouse gases are determined simultaneously in air sampled successively at four heights, between 20 and 200 m above ground level. Rn-222 measurements are performed in air sampled at 20 and 200 m. Th
Since the beginning of statebuilding interventions following the end of the Cold War, they have been strictly focused on rebuilding state institutions, wherever they have taken place. As a growing percentage of states that had experienced civil war relapsed into new intrastate conflicts, it started to dawn on researchers that this approach was inadequate. Focus amongst researchers started to turn
Author: Elisabeth Mårtensson & Marianne Vagnemark Title: “I know myself best” – A study of what people with drug- and alcohol problems believe that they need help with [translated title] Supervisor: Arne Kristiansen Assessor: Gunilla Lindén The purpose of this study was to examine what people with drug- and alcohol problems believe that they need for kind of help if a change would become poss
Brevmall 2018-10-19 Besöksadress Telefon dir Växel E-post Internet Sölvegatan 37 046-222 3782 046-222 0000 Yvonne.Persson@cec.lu.se http://www.miljovetenskap.lu.se Mi l jövetenskapl ig utbi ldning Centrum för mi l jö - o ch k l imatfo rskning Välkommen till kursen Tillämpad Industriell Miljöekonomi (MVET01, HT 2018) Kursen börjar med introduktionsmöte med upprop och efterföljande projektintrodukti
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/valkomstbrev_mvet01_ht18_clx.pdf - 2026-07-17
Subaquatic mosses and stream plants have been recognized as suitable sample media for detection of geochemical variations in their surrounding environments. These plants were originally used in search for mineral deposits but later on also for detection of environmental pollution. In this study it is investigated if statistically significant correlations could be detected between element content i
This paper examines social policy in the European Union with a specific focus on parental leave, in-cluding earmarked paternity leave. It traces the process of how the legislation of parental leave has gone through a process of Europeanization and through the decision-making process of the European Union, resulted in the Directive 2019/1158. Moreover, it aims at examining the Danish knowledge of t
Aim: This thesis aims to develop a deeper understanding of how junior and senior preschool teachers engage in knowledge sharing and learning in a public sector organisation as well as how their knowledge sharing and learning behaviour is being challenged. Literature Review: Our literature review focuses on knowledge and knowledge sharing and relates it specifically to the public sector which corre
This study investigates the relationship between prior entrepreneurial intent and perceived learning outcomes of students entering a new venture creation programme. Previous research in this field has not addressed the influence of prior entrepreneurial intentions on learning outcomes but rather treated entrepreneurial intent as an outcome of entrepreneurship education. Therefore, the aim of this
In the central Himalayas, water dynamics are expected to change due to multiple factors like climate change, hydro power development and shifting land use practices. This thesis looks at possible changes in water dynamics in Marsyandi river basin, Nepal, as well as causes to those changes and how they are perceived locally. Grounded in critical physical geography, the study uses mixed methods an
OBJECTIVE-To evaluate the significance of GAD antibodies (GADAs) and family history for type 1 diabetes (FHT1) or type 2 diabetes (FHT2) in nondiabetic subjects. RESEARCH DESIGN AND METHODS-GADAs were analyzed in 4,976 nondiabetic relatives of type 2 diabetic patients or control subjects from Finland. Altogether, 289 (5.9%) were GADA(+)-a total of 253 GADA(+) and 2,511 GADA(-) subjects participate
OBJECTIVEYounger age at menarche, a marker of pubertal timing in girls, is associated with higher risk of later type 2 diabetes. We aimed to confirm this association and to examine whether it is explained by adiposity.RESEARCH DESIGN AND METHODSThe prospective European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct case-cohort study consists of 12,403 incident type 2 diabetes
Two (Ga,Mn)As samples having different magnetic anisotropy (one with in-plane easy axis and another one with out-of-plane easy axis) were studied by means of magnetotransport experiments. Anisotropy field B-A was determined for both samples as a function of temperature. For the sample having in-plane easy axis, an inversion of the direction of planar Hall effect hysteresis was observed upon increa
The association between vitamin D status and hepatocellular carcinoma (HCC) has not been well investigated, despite experimental evidence supporting an important role of vitamin D in liver pathophysiology. Our objective was to investigate the association between prediagnostic circulating 25-hydroxyvitamin D [25(OH)D] serum levels and the risk of HCC in a prospective, nested case-control study amon
Assessment of the long-term safety and efficacy of liquid inhaled insulin via AERx((R)) insulin Diabetes Management System (iDMS) in a basal/bolus treatment regimen of adults with Type 1 diabetes. Patients were randomized 2 : 1 to prandial inhaled (n = 205) or subcutaneous (s.c.) (n = 99) insulin, plus one/two daily injections of neutral protamine Hagedorn (NPH) insulin for 12 months. The primary
Lipid A (a hexaacylated 1,4' bisphosphate) is a potent immune stimulant for TLR4/MD-2. Upon lipid A ligation, the TLR4/MD-2 complex dimerizes and initiates signal transduction. Historically, studies also suggested the existence of TLR4/MD-2-independent LPS signaling. In this article, we define the role of TLR4 and MD-2 in LPS signaling by using genome-wide expression profiling in TLR4- and MD-2-de
OBJECTIVES: To explore the development of hypertension (HT) in a cohort of young middle-aged men. DESIGN: Prospective birth-cohort study of men surveyed over 6 years. SETTING: Helsingborg County Hospital, Sweden, 1990-97. SUBJECTS: A total of 628 men born in 1953-54, all surveyed at 37, 40 and 43 years of age. MAIN OUTCOME MEASURES: Systolic blood pressure (SBP), diastolic blood pressure (DBP), S-
Qusta ibn Luqa (fl. 860) was a prominent figure in the Graeco-Arabic translation movement that reached its peak in the 9th century. At the request of wealthy and influential commissioners, Qusta translated Greek works on astronomy, mathematics, mechanics and natural science into Arabic. He also produced works of his own: more than sixty treatises are attributed to him. He wrote mainly on medical s
