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The impact of different climate scenarios, drought, and water level management on the outflow water quality of peatlands has been investigated. A mesocosm experiment has been conducted within climate control chambers to simulate current (2016–2019 real-time) and future representative concentration pathway (RCP) climate scenarios (RCP 2.6, 4.5 and 8.5). To assess the efficiency of a management stra

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The late Cambrian Steptoean positive carbon isotope excursion (SPICE) represents a major perturbation to the global carbon cycle and was associated with trilobite extinctions and expansion of anoxic and/or euxinic water masses during episodes of eustatic sea-level change. We present a new Re-Os age together with Os and Nd isotope stratigraphy and major and trace-element data from the Alum Shale Fo

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We consider the calculations of photoionization spectra and core resonances of open-shell systems using range-separated time-dependent density-functional theory. Specifically, we use the time-dependent range-separated hybrid (TDRSH) scheme, combining a long-range Hartree-Fock exchange potential and kernel with a short-range potential and kernel from a local density-functional approximation, and th

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3-Bromo-2-(bromomethyl)propyl (dibromoisobutyl or DIB) mono- to tetrasaccharide glycosides were prepared in moderate to high yields by treatment of the corresponding 1-0-acetyl saccharides with 3-bromo-2-(bromo-methyl)propanol (DIBOL) and boron trifluoride etherate. Treatment of the DIB glycosides with alkyl- and ω-methoxycarbonylalkyl thiols gave the corresponding bis-sulfide glycolipids and spac

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Type 2 diabetes (T2D) is a polygenic disease and studies to understand the etiology of the disease have required selectively bred animal models with polygenic background. In this review, we present two models; the Goto-Kakizaki (GK) rat and the Oikawa-Nagao Diabetes-Prone (ON-DP) and Diabetes-Resistant (ON-DR) mouse. The GK rat was developed by continuous selective breeding for glucose tolerance f

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Background: Germinal matrix-intraventricular haemorrhage (GMH-IVH) and encephalopathy of prematurity (EoP) remain substantial issues in neonatal intensive care units worldwide. Current therapies to prevent or treat these conditions are limited. Stem cell-based therapies offer a potential therapeutic approach to repair, restore, or regenerate injured brain tissue. These preclinical findings have no

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Hip-related pain is an umbrella term encompassing pain from non-arthritic hip joint pathologies, such as femoroacetabular impingement syndrome, hip dysplasia, and labral tears. Exercise therapy is commonly recommended for these conditions, but the reporting completeness of these interventions is currently unclear. Purpose The aim of this systematic review was to assess the reporting completeness o

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Accurate assessments of symptoms and illnesses are essential for health research and clinical practice but face many challenges. The absence of a single error-free measure is currently addressed by assessment methods involving experts reviewing several sources of information to achieve a best-estimate assessment. This assessment method is called the Expert Panel method in medicine, and the Best-Es

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In recent years, researchers have extensively investigated hepatocellular carcinoma (HCC), a prevalent cancer type worldwide. Its resistance to conventional treatments highlights the promise of theragnostic nanoparticles, offering multiple tools within a single platform for fighting HCC cells. In this research, using polyaniline (PANI)-coated cobalt ferrite nanoparticles (CFO), an innovative nanoc

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School-related functional impairment is common in children and adolescents with obsessive-compulsive disorder (OCD). However, little is known about the characteristics of youth with OCD who struggle in school, whether these struggles interfere with treatment outcomes, and whether treatment improves school-related function. Among 385 youth with OCD at a specialist clinic (mean age [sd] = 13.7 [2.5]

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This thesis discusses the use of standards in land-use planning risk management regulations. Based on exploring the domains of standards and standardisation, risk science, and risk management regulations, the research contributes significant empirical evidence capturing the perspectives of risk managementpractitioners in terms of the strengths, the weaknesses and the effects of using standards in

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A report of the Sweden new government on the future for bioenergy is presented. The report state that the agriculture sector supplies 1.5 TWh of biomass energy to the Swedish energy system in the form of wheat, rapeseed, and some willows. A report discloses the fact that agriculture can play an important role in the development of Swedish energy system in the future. The most profitable crops for

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One of the main challenges in regenerative medicine is the spatiotemporal control of angiogenesis, which is key for the successful repair of many tissues, and determines the proper integration of the implant through the generation of a functional vascular network. To this end, we have designed a three-dimensional (3D) model consisting of a coaxial binary elastin-like recombinamer (ELR) tubular con

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Objective: This study aims to provide a deeper understanding of what persons with lived experience and professionals with experience of patient safety, suicide research, and investigations consider to be most important in investigations of healthcare before suicide to learn and improve the care of suicidal patients. Method: This is a qualitative study based on 15 semistructured interviews with per

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In the effort to obtain a precise measurement of leptonic CP-violation with the ESSνSB experiment, accurate and fast reconstruction of detector events plays a pivotal role. In this work, we examine the possibility of replacing the currently proposed likelihood-based reconstruction method with an approach based on Graph Neural Networks (GNNs). As the likelihood-based reconstruction method is reason

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PURPOSE: Techniques for endovascular thrombectomy in acute ischemic stroke due to medium or distal vessel occlusions (MDVO) need to be improved, and first-line aspiration is emerging as a promising technique. The objective was to describe first-pass and final reperfusion rates with a triaxial direct aspiration first pass technique (ADAPT) and a novel, quadriaxial technique (QUATTRO-ADAPT) using RE

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Background: Magnetic resonance imaging (MRI) is recommended by guidelines to evaluate the severity of brain ischemia after cardiac arrest for functional outcome prediction. However, standardized assessment criteria are lacking. We have developed a semi-quantitative Cardiac Arrest Brain Ischemia (CABI) score to assess the extension of brain ischemia on MRI. Objectives: To evaluate the prognostic pe

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Provision of assistive technologies (AT) is strongly connected to applying a person-centred approach, with focus on exploring the person’s individual abilities, needs and desires, to enable provision of matching AT. In the process of provision, it is also important to assess and facilitate the person’s understanding of how to use the AT, to enhance optimal usage and enable AT integration in everyd

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Objectives: Our aim was to compare direct costs for single pill combinations (SPCs) and free-drug combinations for hypertension treatment. Methods: We focused on Australia as a case study and reviewed total costs, and for the patient and government. We reviewed the Australian “Pharmaceutical Benefits Scheme item drug map” considering different thresholds for the government safety net. Total costs