Filtyp
This thesis employs a historical institutionalist lens to analyze whether the gendered impacts of COVID-19 have initiated a critical juncture in The Hunger Project’s program policy. Crises such as COVID-19 may lead actors within organizations to question existing policies, giving them greater opportunities than normal to transform these, with lasting consequences. Theory-testing process-tracing is
The COVID-19 pandemic has been one of the deadliest health crises in modern history. Increasing production of all relevant medical goods and ensuring their equitable distribution has been argued as a necessity to contain the pandemic, which led to the South African and Indian delegation in the TRIPS Council of the World Trade Organization to propose the implementation of a TRIPS waiver to ensure t
Världen är för närvarande på väg mot 3°C av global uppvärmning pga globala koldioxidutsläpp. Kunskapen som krävs för att minska utsläppen existerar, men de radikala sociala och politiska förändringar som behövs sker hittills inte snabbt nog. Nuvarande politiska och ekonomiska paradigm hyllar koldioxidprissättning som antingen den enda lösningen, alternativt som en del av lösningen. Denna uppsats tThe world is currently heading for 3°C of global warming due to global excessive carbon emissions, and while science is producing the knowledge necessary to combat it, the radical change needed is not coming fast enough. Current political and economic paradigms hail carbon pricing as either the, or part of the solution to our carbon emissions problem. This thesis looks at the available (although l
Micropollutants, such as pharmaceutical residues, are increasingly prevalent in water sources, posing significant risks to human and animal health while contributing to antimicrobial resistance. Despite high-standard wastewater treatment across the EU, the effective removal of micropollutants requires the adoption of more advanced treatment technologies, specifically quaternary treatment technolog
Background: Familial clustering of incident prostate cancer and some cancers at other discordant sites has been reported. Less is known about familial clustering of fatal prostate cancer with any fatal discordant cancers. Estimates on familial aggregation based on mortality are free from bias of overdiagnosis. Patients and methods: We used the nationwide Swedish Family-Cancer Database to calculate
The analysis of annual extremes of hydrological and meteorological variables is frequently complicated by the presence of gaps in record, and when records are not only fragmented but also short, it is necessary to utilize to the full the information contained in them. One method is to abstract for statistical analysis all extreme events whose peaks exceed a pre-selected threshold value, but the th
Abstract in FinnishSex-determination is commonly categorized as either "genetic" or "environmental"-a classification that obscures the origin of this dichotomy and the evolution of sex-determining factors. The current focus on static outcomes of sex-determination provides little insight into the dynamic developmental processes by which some mechanisms acquire the role of sex determinants. Systems
Making the built environment accessible for all regardless of functional capacity is an important goal for public health efforts. Considerable impediments to achieving this goal suggest the need for valid measurements of acccessibility and for greater attention to the complexity of person-environment fit issues. To address these needs, this study aimed to provide a methodological platform, useful
Background Starting in the 1960s, a broad-based patients’ rights movement began to question doctors’ paternalism and to demand disclosure of medical information, informed consent, and active participation by the individual in personal health care. According to scholars, these changes contributed to downplay the biomedical approach in favor of a more patient-oriented perspective. The Swedish non-p
Endosomal entrapment is known to be a major bottleneck to successful cytoplasmic delivery of nucleic acids (NAs) using cationic liposome-NA nanoparticles (NPs). Quantitative measurements of distributions of NPs within early endosomes (EEs) have proven difficult due to the sub-resolution size and short lifetime of wildtype EEs. In this study we used Rab5-GFP, a member of the large family of GTPases
A hollow fiber supported liquid membrane module using one single fiber impregnated with a mixture of 1,10-dibenzyl-1,10-diaza-18-crown-6 and bis(2-ethylhexyl)phosphate dissolved in hexylbenzene was used for passive sampling of ppb levels of Pb(II), Cu(II), Zn(II), Mn(II), Ni(II), and Cd(II) in water. The target ions were simultaneously transported and preconcentrated into a citric acid acceptor so
Background: To study costs and outcome for serious hand and arm injuries during the first year after the trauma. Methods: In patients with a Hand Injury Severity Score (HISS) > 50, DASH and EQ-5D scores as well as factors related to costs within the health care sector, costs due to lost production and total costs were evaluated. Coxregression analysis stratifying for mechanism of injury was used t
We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - Septemb
Purpose: To assess baseline factors that may predict fast tibiofemoral cartilage loss over a 30-month period. Materials and Methods: The Multicenter Osteoarthritis (MOST) study is a longitudinal study of individuals who have or who are at high risk for knee osteoarthritis. The HIPAA-compliant protocol was approved by the institutional review boards of all participating centers, and written informe
Breast cancer is the most common cancer form among women in the Western world. Although treatment has improved during the last decades, there is still a significant proportion of the patients who are not cured. To further improve clinical outcome we need new treatment strategies, new prognostic markers, and new treatment predictive factors for personalized medicine.In this dissertation I have focu
High uncertainties are common in detailed quantification of the N budget of agricultural cropping systems. The process-based CoupModel, integrated with the parameter calibration method known as Generalized likelihood uncertainty estimation (GLUE), was used here to define parameter values and estimate an N budget based on experimental data from an organic farming experiment in south-west Sweden. Da
We study the mechanical failure of cemented granular materials (e.g., sandstones) using a constitutive model based on breakage mechanics for grain crushing and damage mechanics for cement fracture. The theoretical aspects of this model are presented in Part I: Tengattini et al. (2014), A thermomechanical constitutive model for cemented granular materials with quantifiable internal variables, Part
Technology foresight studies have become an important tool in identifying realistic ways of reducing the impact of modern energy systems on the climate and the environment. Studies on the future cost development of advanced energy technologies are of special interest. One approach widely adopted for the analysis of future cost is the experience curve approach. The question is, however, how robust
Aim: To compare treatment costs with alternative luteinizing hormone-releasing hormone (LHRH) agonist preparations and determine whether a leuprorelin solid implant is associated with potential cost savings. Patients & methods: A hypothetical population of 1000 prostate cancer patients was apportioned between the three most commonly-prescribed LHRH agonist preparations. Differentiated annual c
