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Deep learning has shown promise for gaze estimation in Virtual Reality (VR) and other head-mounted applications, but such models are hard to train due to lack of available data. Here we introduce a novel method to train neural networks for gaze estimation using synthetic images that model the light distributions captured in a P-CR setup. We tested our model on a dataset of real eye images from a V
Polarized neutron imaging brings the great advantage of analyzing bulk magnetic properties with good spatial resolution. The technique is based on the interaction of the neutron spin with magnetic samples or free magnetic fields and observing the changes to a spin-polarized neutron beam. The high sensitivity to even small magnetic fields is a benefit in obtaining magnetization information but simu
Objective: To investigate how a behavioral health, artificial intelligence (AI)-powered, digital self-management tool affects the daily functions in adults with chronic back and neck pain. Design: Eligible subjects were enrolled in a 12-week prospective, multicenter, single-arm, open-label study and instructed to use the digital coach daily. Primary outcome was a change in Patient-Reported Outcome
Objective: Analyze the outcomes of endovascular complex abdominal and thoracoabdominal aortic aneurysm repair using the Cook fenestrated device with the modified preloaded delivery system (MPDS) with a biport handle and preloaded catheters. Methods: A multicenter retrospective single arm cohort study was performed, including all consecutive patients with complex abdominal aortic aneurysm repair an
ObjectiveTo evaluate the ACR/EULAR 2022 criteria for ANCA-associated vasculitides (AAV) classification and compare them with the European Medicines Agency (EMA) algorithm and with classification based only on ANCA serology.MethodsIn the analysis, 374 cases (47% female) were classified according to the EMA algorithm, ANCA serology and ACR/EULAR criteria. The agreement rate was calculated using the
The COVID-19 pandemic has jolted the health system globally and a paucity of specific drugs and/or vaccine hesitancy led clinicians to indiscriminately use antibiotics. Furthermore, during the early waves of the COVID-19 pandemic, several studies showcased the anti-SARS-CoV-2 efficacy of few antibiotics which further catapulted the idea of using them after emergency approval by the Food and Drug A
Forests are invaluable terrestrial ecosystems with considerable economic, ecological, and environmental benefits. Bark beetles have been recognized as one of the major causes of forest disturbance, and climate change can exacerbate their impact, leading to more tree mortality. Early detection of bark beetle attacks is vital to reduce forest loss and devastating consequences. This study examines th
High aspect ratio nanostructuring requires high precision pattern transfer with highly directional etching. In this work, we demonstrate the fabrication of structures with ultra-high aspect ratios (up to 10 000 : 1) in the nanoscale regime (down to 10 nm) by platinum assisted chemical etching of silicon in the gas phase. The etching gas is created by a vapour of water diluted hydrofluoric acid and
Adjuvants have traditionally been appreciated for their immunoenhancing effects, whereas their impact on immunological memory has largely been neglected. In this paper, we have compared three mechanistically distinct adjuvants: aluminum salts (Alum), Ribi (monophosphoryl lipid A), and the cholera toxin A1 fusion protein CTA1-DD. Their influence on long-term memory development was dramatically diff
Over the last decades, marketing literature has persistently been interested in how marketers and consumers alike engage with the past through past-themed brands, products, and services. However, our knowledge on past-themed marketing is scattered and treated in largely separated literature streams on retro, heritage, nostalgia, and vintage. This article reviews marketing literature on retro, heri
Phlorotannins, the polyphenols mostly found in brown seaweeds, have attracted high attention from the pharmaceutical industry in recent years due to their antioxidant, antibacterial, and anti-inflammatory activities. These properties make them desirable to be utilized in a wide range of therapeutics. Despite their importance, several challenges make their extractability and identification complex,
In septic shock, administration of large fluid volumes is associated with poor outcomes. Recent evidence shows that non-resuscitation fluids are the major modifiable source of fluids for patients with septic shock in intensive care units (ICUs). This clinical trial is designed to test the hypothesis that restrictive administration of non-resuscitation fluids improves outcomes compared to usual car
As rapid urbanization intensified pressure on coastal ecosystems, balancing economic development with ecological preservation remained a critical challenge. This study developed a multi-criteria framework for integrated marine spatial planning and applied it to Shenzhen, China—a rapidly expanding coastal metropolis overseeing 1145 km2 of marine territory with a 260.5 km coastline, 61.47% of which
As novel, anti-amyloid therapies have become more widely available, access to timely and accurate diagnosis has become integral to ensuring optimal treatment of patients with early-stage Alzheimer's disease (AD). Plasma biomarkers are a promising tool for identifying AD pathology; however, several technical and clinical factors need to be considered prior to their implementation in routine clinica
In contemporary enterprises, customer satisfaction analysis has become a critical area of concentration. Being able to understand and predict customer satisfaction is becoming more and more important as companies try to develop and launch new products. Leveraging customer data intelligently and employing robust data analytics techniques are essential for meeting this imperative. With this objectiv
Jordbruket är grundläggande för livsmedelssäkerhet och försörjning på landsbygden, men sektorn står inför varaktiga hållbarhetsutmaningar. Moderna produktionssystem har ökat avkastningen men också bidragit till markförstöring, förlust av biologisk mångfald och utsläpp av växthusgaser. Denna avhandling undersöker hur jordbrukspolitiska styrmedel kan utformas för att förbättra både den ekonomiska efAgriculture is fundamental to food security and rural livelihoods, but the sector faces persistent sustainability challenges. Modern production systems have increased yields but also contributed to soil degradation, biodiversity loss, and greenhouse gas emissions. This thesis examines how agricultural policy instruments can be designed to improve the economic efficiency and environmental effective
Several studies have reported that heterosexual women's preferences for male faces vary with hormonal fluctuations over the menstrual cycle and that women tend to prefer more masculine faces during ovulation or when not using hormonal contraceptives. While this has been tested using observational data, we provide the first double-blind randomized controlled study testing if oral contraceptives red
Background: In this study, we further developed an artificial intelligence (AI)-based method for the detection and quantification of tumours in the prostate, lymph nodes and bone in prostate-specific membrane antigen (PSMA)-targeting positron emission tomography with computed tomography (PET–CT) images. Methods: A total of 1064 [18F]PSMA-1007 PET–CT scans were used (approximately twice as many com
