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BACKGROUND: This phase 3 study further characterizes the efficacy and safety of reslizumab (a humanized anti-interleukin-5 monoclonal antibody) in patients aged 12-75 years with asthma inadequately controlled by at least a medium-dose inhaled corticosteroid, and blood eosinophils ≥400cells/μL.METHODS: Patients were randomized to receive reslizumab 0.3 or 3.0mg/kg or placebo once/every 4 weeks/16 w
Depending on the maximum amplitude of externally applied cyclic electric fields, ferroelectric ceramics show minor or major hysteresis. The materials also show asymmetric butterfly hysteresis in a prepoled material. Aiming at capturing these behaviour in a phenomenological constitutive model, a multi-surface modelling approach for ferroelectrics is introduced. In this paper, with the note on the m
In this work we present the quasi-steady state simulation of a regenerative organic Rankine cycle (ORC) integrated in a passenger vessel, over a standard round trip. The study case is the M/S Birka Stockholm cruise ship, which covers a daily route between Stockholm (Sweden) and Mariehamn (Finland). Experimental data of the exhaust gas temperatures, engine loads, and electricity demand on board wer
Mental health problems affect the patients and their families, who may also need therapeutic interventions. Mindfulness interventions have shown beneficial health effects for clinical and healthy populations. A web-based mindfulness intervention was tailored to address families' needs of support and tested in a pilot intervention study. The aim of this study was to explore the participants' experi
An enhanced dual-layer wide area wireless sensor network (WSN) system was developed and applied in fresh food tracking application. The sensor nodes of WSN provide a set of useful measurements about the environmental conditions during the fresh food transportation. Since the 3-axis acceleration data in such application account for more than 99% out of all collected source data, we propose a novel
By pulse-modulating a cw dye-laser beam and employing the delayed-coincidence technique, we have determined the natural radiative lifetimes of a number of atomic states in rare-earth atoms Eu, Dy, and Yb. In the measurements, which were performed on an atomic beam, exponential decay curves with good statistics were obtained using short measuring times. The general features of the technique are dis
Vocal learning is a critical behavioral substrate for spoken human language. It is a rare trait found in three distantly related groups of birds-songbirds, hummingbirds, and parrots. These avian groups have remarkably similar systems of cerebral vocal nuclei for the control of learned vocalizations that are not found in their more closely related vocal non-learning relatives. These findings led to
Temperature limitations of Solid Oxide Fuel Cells (SOFC) in transient single operation and steady-state Hybrid System (HS) operation with Gas Turbines (GT) are presented. For transient SOFC simulations, an unsteady-state SOFC model was developed by upgrading a detailed validated steady-state model. As critical SOFC single operation modes, concerning the risk of material cracking due to exceeding S
This article addrsses the advant of this online only publication, the very context in which it is being made available. Central to this article is Delanty's work on communicative communities. It is argued that it is particularly appropriate to view comparative and international education in this manner. Online publication offers comparative and international education a new context of meaning. See
Desalination can be a cost-effective way to produce fresh water and possibly electricity. The Gaza Strip has had a complex hydro-political situation for many years. Gaza is bordered by the Mediterranean in the west, by Israel in the north and east and by Egypt in the south. Water and electricity consumption in the Gaza Strip is expected to increase in the future due to the increasing population.
