Sökresultat

Utvärdering av ett målprotein för behandling av ledgångsreumatism Reumatisk artrit (RA), eller ledgångsreumatism som det också kallas, är en autoimmun sjukdom som 1% av världens befolkning lider av. Kroppens egna immunceller blir autoreaktiva och attackerar lederna i främst händer och fötter. Den ökade mängden immunceller i de här lederna resulterar i svullnad och inflammation, men även ben och bRheumatoid arthritis is an autoimmune disease resulting in swelling and destruction of bone and cartilage within the small joints. The mechanism behind the disease is not fully understood, but the interaction of autoreactive T-cells with effector cells like B-cells and macrophages through cytokine signaling is believed to be important. A potential target for drug development against arthritis that

Modern democracies face many challenges including declining voter turnout and growing mistrust towards political representatives. An increased trend among representative democracies facing these challenges is to introduce different direct democratic instruments. The aim of this thesis is to find what explains the introduction of the national citizens’ initiatives in Finland. During the last few de

Increasing awareness and change in attitudes towards environment has given rise to the sustainable development and this development has stimulated environmental innovations globally in the last years. The recent studies show that in near future there will be more packaging solutions from renewable resources. The purpose of this thesis is to investigate how a brand owner using renewable packaging m

This master thesis work consists of the development of new hardware and software for the control box of an azimuthal guidance system used by aircrafts during the approach to the runway. The thesis work was done at Safegate International AB as a project running along the usual development projects. When designing electronics to be used on an airfield there are a lot of regulations and standards t

Total resection of glioblastoma multiform (GBM), the most common and aggressive malignant brain tumor, continues to be a challenge. Achieving complete resection is limited by difficulty in intraoperative discrimination between normal and residual tumor cells. This project contributes to the development and evaluation of a fiber-optical based fluorescence/reflectance spectroscopy system as an intra

Rhinosinusitis is the fifth most common diagnosis for which antibiotics are prescribed- but it is often done in vain. Currently, the only way to fully determine whether or not such treatment is actually needed is an invasive procedure. In order to spare patients from the discomfort that it would involve, this essential step is often skipped and instead, antibiotics are prescribed regardless. Using

This research proposes that an interdisciplinary approach to understanding the concept of culture and culture change could be beneficial for Sustainable Development. It explores the transferability of the DIKT Learning Model and theory of Creative Populations, originally found in management literature, and applies them to a social change corporation in Medellin, Colombia. The corporation analyzed

Design of a concrete column with biaxial moments and normal force is unpractical without the aid of a computer program. It is very time consuming to go through all calculations and to find a suitable layout of a cross-section and positioning of reinforcement for the final design. The goal of this thesis is to create a user friendly computer program for this problem. A critical pier in the Öland B

Title: The use of art for branding purposes - A study of Louis Vuitton’s art collaborations Louis Vuitton’s creative director, Marc Jacobs, personally describes the fine arts as being higher up in the social hierarchy than fashion. After all, it is known as the ultimate luxury item. This essay will explore the way that the brand uses art in various ways as a means of branding. After extensive res

Title: Improving the packaging material availability for internal testing - A case study at Tetra Pak Keywords: Supply chain management, process mapping, procurement, visibility, order handling, supply chain information systems. Background: For any business, optimizing the supply chain is beneficial and can be a crucial competitive advantage. Additionally, the significance of optimization is eve

Several researchers have approached the subject of VUCA and the challenges of operating in a VUCA world. However, previous research seldom addresses specifically how the work can be done or how these qualities and skills can be developed. The purpose of this study is to help professionals responsible for competence development in their work to enable employees to handle a VUCA world. Therefore, th

In this project, a neutron delivery system for the study of free neutron oscillations at the HIBEAM beamline at the European Spallation Source (ESS) has been developed. The HIBEAM experiment is part of a two-stage program at ESS which will address open questions in physics; specifically the nature of dark matter and the observed asymmetry between matter and antimatter in the Universe. This will be

An important factor in preventing food waste is the ability to provide a product with a package according to its needs. The packaging material, in turn, needs to be recyclable in order to contribute to a circular use of materials rather than becoming waste. The aim of this thesis is to examine the difference between the current and future packaging material of coffee produced by Zoégas. The curren

Strong narrowband interference can significantly degrade the sensitivity of wideband receivers by driving front-end circuitry into nonlinear operation. This thesis presents the design, fabrication, and measurement of a 2 – 4.4 GHz electrically tunable varactor-based bandstop filter that can follow and block such narrowband interference before it causes problems in the receiver. It was developed us

Aortic valve stenosis is a common congenital heart defect among children. In affected patients, the normal tricuspid valve structure is malformed into a bicuspid valve structure due to a fusion at one commissure. A common treatment is transcatheter balloon valvuloplasty, where a balloon is inserted through the aortic valve and inflated to mechanically tear the fused region, restoring a tricuspid s

This study investigates the optimization of Cleaning-In-Place (CIP) programs for Ultra-High Temperature (UHT) equipment used in oat drink production. The research comprises three main experiments: an Identification of the largest cleaning load product, an Assessment of improved CIP programs, and an Investigation of deposit composition in the flash cooler. The Identification of the largest cleanin

Introduction Illicit maritime activities frequently involve "dark" vessels that disable or manipulate their Automatic Identification System (AIS) signals to evade detection. This study evaluates the effectiveness of Synthetic Aperture Radar (SAR) and Optical imagery for vessel detection using both “manual” and automated Deep Learning (DL) methods while integrating AIS data to validate, i

Received Signal Strength Indicator (RSSI) circuits are critical in modern Wi-Fi receivers, playing a key role in power management and protecting the radio frequency (RF) front-end from saturation and potential damage. This thesis presents the design and evaluation of a novel rectifier circuit conceptualized for use in an RSSI system within an industry-standard 22nm CMOS node, specifically targetin