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RNA interference (RNAi) has recently been discovered in the budding yeast Saccharomyces castellii. As in other organisms, artificial RNAi could be a useful genetic tool in budding yeast, but the method needs first to be established. S. castellii is also a useful model for telomerase studies, and a knockdown of the telomerase catalytic subunit Est2p could be a new way of unrevealing its functions a
