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This master’s thesis is a comparative study between a structural model and a simulation based model for predicting default-probabilities. The structural model used is the KMV model and the simulation based is a new model called Zero-Price Probability. The main focus is on the new simulation based approach rather than the older established models. The comparison is done to get an implicit idea of t
The purpose of this essay is to examine how Nepal has implemented article 28 of the UN Convention on the Rights of the Child (CRC). The essay focuses on subdivision 1(a) in the article which establishes that all States Parties shall make primary education compulsory and free to all children within their country. Through the ratification of the CRC the Government of Nepal is under the obligation to
Objective: To limit the research time by developing a theoretical model, that can predict the lifetime of a wheel with the help of different input values. Apart from a theoretical model, also create a different type of test rig that can decrease the testing time, and still produce an accurate result similar to a real situation. Method: This Master’s Thesis was based on both an investigatory method
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The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will hel
Companies are constantly being pressured to innovate in order to stay competitive in the short run and have new offerings in the long run. One way of boosting innovation is to develop idea support systems that go beyond the traditional methods and tools. Through a qualitative study, this paper explores the lessons learned from developing an online platform for idea generation, and discusses it in
BACKGROUND: Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. It is therefore of importance to evaluate the optimal use of different markers of cobalamin/folate status in a psychogeriatric population. METHODS: We measured serum cobalamin, blood folate, plasm
Non-typable Haemophilus influenzae (NTHi) is an important human-specific respiratory pathogen colonizing the mucosa of the upper respiratory tract. The bacterium is a common cause of acute otitis media in children and exacerbations in patients with chronic obstructive pulmonary disease (COPD). An immunoglobulin (Ig) D-lambda myeloma protein was found to detect a 16kDa surface protein that we desig
Purpose We have recently presented a decision support system for interpreting myocardial perfusion scintigraphy (MPS). In this study, we wanted to evaluate the system in a separate hospital from where it was trained and to compare it with a quantification software package. Methods A completely automated method based on neural networks was trained for the interpretation of MPS regarding myocardial
The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their extracted data matrices, and information about the physical array, the features and reporter molecules. We present a web-based customizable bioinformatics solution called BioArray Software Environment (BASE) for the
The demand for highly purified plasmids in gene therapy and plasmid-based vaccines requires large-scale production of pharmaceutical-grade plasmid. Plasmid DNA was selectively precipitated from a clarified alkaline lysate using the polycation poly(N,N'-dimethyldiallylammonium) chloride which formed insoluble polyelectrolyte complex (PEC) with the plasmid DNA. Soluble PECs of DNA with polycations h
Objectives The aim of this study was to identify risk factors for cardiovascular malformation. Methods In a case-referent study prospectively collected data were obtained from original medical records. The study included 277 woman who had infants with a severe cardiac defect, and for each case two referents (medical records study) were included. Data on parental age, maternal reproductive history,
BACKGROUND AND OBJECTIVE: Infection after transrectal prostate biopsy (TPBx) is a well-known risk. A comprehensive investigation of risk factors may identify measures for safe TPBx as an alternative to a change in biopsy route. The aim of this study was to identify risk factors for infection after TPBx.METHODS: We included all outpatient TPBx cases in Region Kronoberg, Sweden, from January 2010 to
Compact in-memory computing architectures are desirable to embed artificial intelligence (AI) in resource-restricted edge devices. However, current technologies face limitations in both the area and energy efficiency. Here, a reconfigurable ferroelectric tunnel field-effect transistor (ferro-TFET) is presented that can be used as an ultra-scaled cell for low-power in-memory data processing. A gate
Autoignition of a homogeneous mixture is very sensitiveto operating conditions. Therefore fast combustion phasingcontrol is necessary for reliable operation. There areseveral means to control the combustion phasing of a Homogeneous Charge Compression Ignition (HCCI) engine.This paper presents cycle-to-cycle cylinder individual controlresults from a six-cylinder HCCI engine using a VariableValve Ac
BACKGROUND: To have an impact on the population's health, preventive interventions have to reach a large proportion of the intended population. Digital solutions show potential for providing wider access to fall preventive exercise. However, there is a lack of knowledge about how to reach the target group. The aim of this study was to describe the recruitment process used in the Safe Step randomis
