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During amino acid starvation the Escherichia coli stringent response factor RelA recognizes deacylated tRNA in the ribosomal A-site. This interaction activates RelA-mediated synthesis of alarmone nucleotides pppGpp and ppGpp, collectively referred to as (p)ppGpp. These two alarmones are synthesized by addition of a pyrophosphate moiety to the 3 position of the abundant cellular nucleotide GTP and
Measuring innovation is a challenging but essential task to improve business performance. To tackle this task, key performance indicators (KPIs) can be used to measure and monitor innovation. The objective of this study is to explore how KPIs, designed for measuring innovation, are used in practice. To achieve this objective, the author draws upon literature on business performance in accounting a
Aims: Transforming growth factor-beta (TGF-β) exists in three isoforms TGF-β1, -β2, and -β3. TGF-β1 has been suggested to be important for maintaining plaque stability, yet the role of TGF-β2 and -β3 in atherosclerosis remains to be investigated. This study explores the association of the three isoforms of TGF-β with plaque stability in the human atherosclerotic disease. Methods and results: TGF-β
This paper aims at identifying the general determinants of the catching-up process. A tentative theory of catch-up, which takes several conventional determinants into account, is deliberately set up on the basis of previous research in this area. The comparative analysis of Singapore and Malaysia provides empirical evidences for testing those determinants. This study mainly focuses on the role of
This master thesis work was performed in collaboration with BioGaia AB, a Swedish biotech- company producing probiotic supplements containing the bacteria Limosilactobacillus reuteri. The products provided by BioGaia contain live microorganisms. Therefore, a method suitable for the correct enumeration of living cells is crucial in probiotic samples and today the so-called plate count method is use
We address a new agricultural policy concern following the decoupling of CAP direct payments in 2005: passive farming, whereby landowners maintain their agricultural area to collect payments without producing commodities. It is claimed that passive farming is hindering agricultural development by 'blocking' access to farmland for expanding farmers. We evaluate the links between the EU's Single Pay
Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute liver injury (APAP-ALI) and justifies development of anti-inflammatory therapies with therapeutic efficacy beyond the therapeutic window of the only current treatment option, N-acetylcysteine (NAC). The inflammatory mediator, h
The Great East Japan earthquake and tsunami hit coastal cities in Iwate, Miyagi and Fukushima Prefectures of Tohoku Region devastating the energy supply system in the region. Electricity and fuel shortages caused severe problems in the city of Kamaishi varying from lack of mobility, communication, heating to reduced health conditions. This paper, aims to analyze the impacts of the earthquake and t
Purpose: The aim of this thesis is to explore the transition towards a hybrid work model and the implications it may have on the use and adaptation of management control within PSFs. The purpose is further to highlight the reasons behind the adaptations of MCS. Methodology: A qualitative single case study of a professional service firm, with empirical data collected through semi-structured interv
Doktorandkurs vid Institutionen för informatik Kursöversikten nedan är skriven på engelska. Course overview This is an intermediate course in information systems (IS) research. The assumption is that course participants have already taken (or will be taking) an introductory course in research in IS that covers some of the foundational elements of research within the IS academic discipline. The IS
