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The Chicxulub asteroid that ended the Cretaceous Era ∼66.05 million years ago caused a prolonged time of global darkness – the impact winter – leading to mass extinctions. Elements from the asteroid, including the platinum group elements (PGEs) osmium, iridium and platinum are known from the globally distributed boundary clay but their carrier elements have so far been unknown. We identify, for th
Background: Human immunodeficiency virus type 1 (HIV-1) is one of the fastest-evolving human pathogens. Understanding HIV-1 transmission, within-host adaptation, and evolutionary dynamics is pivotal for development of interventions and vaccines. HIV-1 infection is generally caused by a single transmitted founder virus (TFV), and TFV sequences are typically obtained using single genome amplificatio
Objectives To investigate the association of diabetes, hypertension and overweight/obesity with physical activity (PA), self-efficacy for pain and self-efficacy for other symptoms before and after a 6- week exercise and education intervention for knee and hip osteoarthritis (OA), and to assess outcome disparities based on metabolic health. Methods Register-based cohort study using the Swedish Oste
Background: Prolonged time to surgery (TTS) after neoadjuvant chemoradiotherapy (nCRT) may enable malnourished oesophageal cancer patients' nutritional status to recover better, possibly improving outcomes with fewer complications and better overall survival (OS) after oesophagectomy. Methods: This is a substudy within a multicentre randomised controlled trial comparing outcomes in patients with o
Background: The globally transmitted avian malaria parasite Plasmodium relictum (lineage SGS1) has been found to infect hundreds of different bird species with differences in infection outcomes ranging from more or less latent to potentially mortal. However, to date basic knowledge about the links between genetic differentiation and variation in infection outcome within this single malaria parasit
Adequate bowel cleansing is essential for high-quality colonoscopy. Recently, a new very low-volume 1 litre (1L) polyethylene glycol (PEG) plus ascorbate solution (ASC) has been introduced. Our aims were to assess the effectiveness and tolerability of this product compared to low-volume 2L PEG-ASC and high-volume 4L PEG solutions, in a real-life setting. In six endoscopy units in Sweden, outpatien
Forest fire is known as an important natural hazard in many countries which causes financial damages and human losses; thus, it is necessary to investigate different aspects of this phenomenon. In this study, performance of four models of linear and quadratic discriminant analysis (LDA and QDA), frequency ratio (FR), and weights-of-evidence (WofE) was investigated to model forest fire susceptibili
There is a great unmet clinical need to identify patients with thin primary cutaneous melanomas (T1, Breslow thickness ≤ 1 mm) who have a high risk for tumour recurrence and death from melanoma. Kin of IRRE-like protein 1 (KIRREL/NEPH1) is expressed in podocytes and involved in glomerular filtration. Screening in the Human Protein Atlas portal revealed a particularly high expression of KIRREL in m
Microsoft Word - Bacteria lab, retroviral production and vector surgery 2019 V2.docx Bacteria lab, Retroviral production and Vector surgery 2019 Report 1. Short description of the platform The main purpose of the platform is to produce high titer viral vectors for research purposes such as stereotactic delivery to the brain or ex vivo transduction with an emphasis on reprograming. The unit consist
Stadgar för EDS Nordic User Group Antagna 2013-10-10 Ändrade 2014-05-16 § 1. Ändamål EDS Nordic User Group, discoverysystemet EBSCO Discovery Services (EDS) nordiska användargrupp, är en ideell förening med uppgift att: * Utbyta erfarenheter och utgöra ett kontaktnät för de bibliotek och organisationer i Norden som använder discoveryssystemet EDS eller EBSCOs länkserver * Samordna och prioritera g
https://www.ub.lu.se/sites/ub.lu.se/files/stadgar_for_eds_nordic_user_group.pdf - 2026-07-22
Magnetic drug targeting is a promising therapy that can benefit patients, as well as provide novel opportunities for pharmaceutical and medical technology/device industries.
Current cardiovascular risk scores do not include obesity or fat distribution as independent factors, and may underestimate risk in obese individuals. Assessment of early vascular ageing (EVA) biomarkers including arterial stiffness, central blood pressure, carotid intima-media thickness and flow-mediated vasodilation may help to refine risk assessment in obese individuals in whom traditional card
Purpose: To compare clinicians and a trained artificial neural network (ANN) regarding accuracy and certainty of assessment of visual fields for the diagnosis of glaucoma. Methods: Thirty physicians with different levels of knowledge and experience in glaucoma management assessed 30-2 SITA Standard visual field printouts that included full Statpac information from 99 patients with glaucomatous
Objectives. To study the course of impairment measured by signals of functional impairment (SOFI) and disability measured by health assessment questionnaire (HAQ) over 20 years in rheumatoid arthritis (RA) patients followed from diagnosis. To explore the contribution of disease activity, joint damage and comorbidity to variation of SOFI and HAQ over time. Methods. RA patients diagnosed 1985-1989 w
PURPOSE: To investigate both the mean daily physical activity and the hour by hour physical activity pattern across the day using accelerometry, and how they are associated with neighborhood walkability and individual income. METHODS: Moderate physical activity (MPA) was assessed by accelerometry in 2,252 adults in the City of Stockholm, Sweden. Neighborhood walkability (residential density, stree
The Archaean block of southern Greenland constitutes the core of the North Atlantic craton (NAC) and is host to a large number of Precambrian mafic intrusions and dyke swarms, many of which are regionally extensive but poorly dated. For southern West Greenland, we present a U-Pb zircon age of 2990 +/- 13 Ma for the Amikoq mafic-ultramafic layered intrusion (Fiskefjord area) and four baddeleyite U-
The risk of post-traumatic osteoarthritis (PTOA) substantially increases following joint injury. Research efforts should focus on investigating the efficacy of preventative strategies in high quality randomized controlled trials (RCT). The objective of these OARSI RCT recommendations is to inform the design, conduct and analytical approaches to RCTs evaluating the preventative effect of joint inju
The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy root s = 8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb(-1). No
When sexually selected traits diverge because of different local selective environments, premating isolation might arise as a correlated response. However, sexually selected traits might also diverge by stochastic forces. Here, we show that odour-based mate preferences and scent composition have diverged between islet- and mainland populations of Skyros wall lizard, Podarcis gaigeae. We quantified
