Filtyp
A socially mixed population is a political ambition in Stockholm. By providing a mix of tenure alternatives throughout all neighbourhoods this objective could, at least partially, be fulfilled. Since current tenure proportions display a weak balance in many neighbourhoods it could be assumed that governing politicians – by primarily utilizing Stockholm’s vast landownership and municipal housing de
It is estimated that the number of devices connected to the Internet will be 50 billion by 2020. How should a not-so-tech-savvy end user be able to discover and directly interact with a myriad of connected things in an intuitive and comfortable manner? Up until now, smartphones have shown potential for managing the Internet of Things (IoT) environments, but we cannot rely on that technology. Weara
There is an unmet clinical need for objective biomarkers to monitor disease progression and treatment response in Huntington's disease (HD). The aim of this review is, therefore, to provide practical advice for biomarker discovery and to summarise studies on biofluid markers for HD. A PubMed search was performed to review literature with regard to candidate saliva, urine, blood and cerebrospinal f
By utilizing the promising alternative fuel of syngas, and the syngas/diesel dual-fuel reactivity controlled compression ignition (RCCI) is a potential combustion strategy for internal combustion engines. However, the optimal operating parameters for syngas/diesel RCCI engines under wide operating conditions have not been investigated. In this study, the operating parameters include fuel supply, s
During a meeting held in Trento, Italy in March 2017, and organised by the COST Action CHIP ME (IS1303) to discuss about ELSI of genome-editing, many different positions emerged on the possibility to intervene on reproduction and especially on the human embryo. At the time, the Nuffield Council on Bioethics had commissioned a background paper on genome editing, and the corresponding Working Group
Development of antibody drugs against novel targets and pathways offers great opportunities to improve current cancer treatment. We here describe a phenotypic discovery platform enabling efficient identification of therapeutic antibody-target combinations. The platform utilizes primary patient cells throughout the discovery process and includes methods for differential phage display cell panning,
Assessment of breast density at the point of mammographic examination could lead to optimized breast cancer screening pathways. The onsite breast density information may offer guidance when to recommend supplemental imaging for women in a screening program. In this work, performance evaluation of a new software (Insight BD, Siemens Healthcare GmbH) for fast onsite quantification of volumetric brea
Water security offers to the local population an adequate quality and quantity of water for health, economy, livelihoods and ecosystems. Hence, achieving basic levels of water security should be a priority in areas where access to fresh water is scarce. The Punata alluvial fan (Bolivia) is a semiarid zone and an important agricultural zone, where the main source of water is groundwater. Therefore,
Background: Second malignant neoplasms and cardiotoxicity are among the most serious and frequent adverse health outcomes experienced by childhood and adolescent cancer survivors (CCSs) and contribute significantly to their increased risk of premature mortality. Owing to differences in health-care systems, language and culture across the continent, Europe has had limited success in establishing mu
Background. Arterial spin labeling is an MR imaging technique that measures cerebral blood flow (CBF) noninvasively. The aim of the study is to assess the diagnostic performance of arterial spin labeling (ASL) MR imaging for differentiation between high-grade glioma and low-grade glioma. Methods. Cochrane Library, Embase, Medline, and Web of Science Core Collection were searched. Study selection e
The calls for evidence-based public policy making have increased dramatically in the last decades, and so has the interest in evidence-based sustainability studies. But questions remain about what “evidence” actually means in different contexts and if the concept travels well between different domains of application. Some of the most relevant questions asked by sustainability studies are not, and
Public procurement for innovation (PPI) is a powerful, underutilized demand-side innovation policy instrument. How this instrument can contribute to meeting societal challenges, which require goaloriented transformation of socio-technical systems, remains unclear and is explored in this article. This article draws on the transitions and PPI literature to propose transformative processes to which P
Although conventional computer technology made a huge leap forward in the past decade, a vast number of computational problems remain inaccessible due to their inherently complex nature. One solution to deal with this computational complexity is to highly parallelize computations and to explore new technologies beyond semiconductor computers. Here, we report on initial results leading to a device
In the present study, the effect of carbon nanotubes (CNTs) either single walled (SWCNT) or multi walled (MWCNT) on sugar oxidation by Corynascus thermophilus cellobiose dehydrogenase (CtCDH) is investigated. The current observed for the direct electron transfer (DET) communication between the enzyme and the electrode is compared to that of the mediated electron transfer (MET) obtained from CtCDH/
STUDY QUESTION: Is there an association between the number of oocytes retrieved for IVF, and perinatal and obstetric outcomes? SUMMARY ANSWER: No significant association was found between the number of oocytes retrieved and perinatal outcomes, while an association was found for placenta praevia and male gender. WHAT IS KNOWN ALREADY: Previous studies have shown that between 6 and 15 oocytes retrie
In this paper, we present the findings of a Universitas 21 (U21) Graduate Research Project collaboration between Pontificia Universidad Católica de Chile, the University of Nottingham, England, and Lund University, Sweden. This project brought together six doctoral candidates at various stages in their postgraduate careers. The students had conducted qualitative and quantitative inquiry into diver
Smoking is considered the most important preventable risk factor in relation to the development of complications during pregnancy and delivery. The aim of this study was to evaluate the effectiveness of an intensive 6-week gold standard programme (GSP) on pregnant women in real life.
BackgroundAdolescents’ use of alcohol, cannabis and other psychoactive substances has significantly increased in European countries. Parallel to this web-based screening and brief intervention have been disseminated. An important question is if it is based on evidence for effect? Therefore, the aim of this review is to evaluate the evidence for effect. MethodA systematic literature search was per
Universities around the world have increasingly turned to digital infrastructures as a way to revamp the arts and humanities. This article contributes a fresh understanding by examining the material development of HumlabX, a research laboratory for digital humanities at Umea° University, Sweden. Specifically, we approach the empirical case as a timeline of research funding, projects, events, and d
