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Background: Available fluid biomarkers, neuroimaging techniques, and clinical assessments may enhance prediction of conversion to secondary progressive multiple sclerosis (SPMS). Objectives: : To identify robust real-world predictors of MS progression in the literature. Methods: : A systematic review was conducted in EMBASE. A total of 20,338 MS patients from 64 eligible studies were included. A p
Improving energy efficiency in agriculture is key to reducing environmental impact. Lighting in animal buildings is one of the most cost‐effective energy saving measures. Lighting retrofit offers a short payback period, enhances animal welfare and production, and aligns with regulations for phasing out fluorescent lighting. The purpose of this study was to investigate the energy-saving potential o
The first generation of ELT instruments includes an optical-infrared high resolution spectrograph, indicated as ELT-HIRES and recently christened ANDES (ArmazoNes high Dispersion Echelle Spectrograph).ANDES consists of three fibre-fed spectrographs ([U]BV, RIZ, YJH) providing a spectral resolution of ∼100,000 with a minimum simultaneous wavelength coverage of 0.4-1.8 µm with the goal of extending
We aimed to investigate the association between psychotropic drug use (proxy for psychological health) and Complex Regional Pain Syndrome (CRPS) type 1 and type 2 in upper and lower limbs. We also assessed the impact of demographic and socioeconomic factors. From a national record linkage database [4,706,821 individuals (25–64 years); CRPS type 1 = 809; type 2 = 225], prevalence ratios (PR), absol
Developing a robust decision analysis framework for selecting appropriate building envelope assemblies is essential to ensure moisture safety, energy efficiency, and sustainability. Recently, Bayat Pour et al. introduced the inutility decision analysis (IDA) method, which integrates moisture safety criteria with sustainability considerations, including economic and environmental aspects. This stud
The recognition of amine groups by ninhydrin, along with a simple mathematical algorithm, showed that di- and tripeptides derived from dietary protein are the major end products of protein digestion entering the blood postprandially. There are thousands of oligopeptides appearing in the gut during protein digestion. However, the presented study on a pig model clearly shows that peptides longer tha
We study the problems of computing the Voronoi diagram and a triangulation of a set of n2 points with O(logn)-bit coordinates in the Euclidean plane in a substantially sublinear in n number of rounds in the congested clique model with n nodes. First, we observe that if the points are uniformly at random distributed in a unit square then their Voronoi diagram within the square can be computed in O
Fully bio-based spirocyclic monomers with high reactivity and thermal stability in polycondensations, and scalable production from low-cost reactants are attractive alternatives to replace fossil-based terephthalate monomers. To this end, we carefully design and synthesize a dicarboxylate ester monomer with a spiroacetal structure from bio-based pentaerythritol and glyoxylic acid. Polycondensation
BACKGROUND: Diagnosing heart failure with preserved ejection fraction (HFpEF) remains challenging, particularly in older adults. While the Heart Failure Association (HFA)-PEFF and H2FPEF Scores offer structured diagnostic approaches, their clinical utility is still debated. This study aims to compare the diagnostic accuracy of HFpEF Scores versus inclusion criteria used in sodium-glucose cotranspo
Metallic infrastructure, such as steel sheet situated within landfills, poses significant challenges to accurate tracking of leachate using induced polarization (IP) methods. The application of IP method is efficient to delineate leakage; however, the presence of metallic structures can cause an interference on the survey and generate high-chargeability anomalies as observed in field survey. To co
A survey including 3112 responses from individual end users of wood cladding, from Norway, Sweden and Germany, was conducted with questions related to their experience and preferences regarding cladding with and without coatings. Based on these results and established scientific understanding of Service Life Prediction (SLP) of wood cladding, two decision trees were provided to guide end users in
Aqueous zinc-bromine (Zn-Br2) batteries feature operational safety and high-energy and high-power densities, but suffer from polybromide dissolution in the cathode and the low reversibility of Zn metal in the anode. Here, we demonstrate that these challenges can be simultaneously tackled by using a fully exploited imidazolium bromide (MPIBr). An in-depth analysis demonstrates that MPIBr enhances b
(Graph Presented) In the search for new cathode materials for rechargeable lithium batteries, conversion-type materials have great potential because of their ability to achieve high specific capacities via the full utilization of transition metal oxidation states. Here, we report for the first time that copper phosphate can be used as a novel high-capacity cathode for rechargeable Li batteries, ca
The electricity market exhibits significant uncertainty arising from rapid fluctuations in prices, variations in load demand, and the intermittent nature of renewable energy resources. Effectively managing residential energy under these dynamic conditions is a challenging task. Demand Response (DR) offers a practical solution by enabling the flexible scheduling of energy consumption in response to
Background: Sjögren’s disease (SjD) is an autoimmune condition affecting exocrine glands, resulting in decreased saliva and tear production. Aquaporin 5 (AQP5) is a transmembrane water channel playing a central role in water transport. In SjD, deregulation of AQP5 expression, trafficking and interactions with various proteins contribute to the underlying disease mechanisms. Methods: Co-immunopreci
Background Parathyroid surgery is an appropriate alternative for renal hyperparathyroidism (rHPT) in patients in whom medical therapy fails. European morbidity and outcome data for clearly defined cohorts, potentially reflecting contemporary clinical practice, remain scarce. Method Data were extracted from the EUROCRINE® database on all operations for secondary rHPT between 1 January 2015 and 31 D
Global water scarcity requires innovative treatment solutions. This presentation explores three membrane-based concepts advancing from idea to pilot scale: stormwater harvesting with micro-/ultrafiltration (MF/UF), direct membrane filtration (DMF) for wastewater treatment, and a hybrid forward osmosis (FO), membrane distillation (MD), and nanofiltration (NF) system for seawater desalination.The EU
