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Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centres completed a structured questionnaire on cause of death and comorbidities. Kaplan-Meier and Cox pro

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Svår, elakartad och längre gången cancer är ett stort problem i förhindrande av spridda tumörceller i kroppen. I detta sjukdomsstadium är oftast en lindrande (palliativ) behandlingsform enda vägen att välja för att hjälpa patienten. För närvarande sker detta genom att patienten får genomlida extern strålbehandling eller cellgiftsbehandling. Radioaktivt märkta och ”målsökande” antikroppar injicerNew radionuclide therapies in humans should be preceded by experimental animal therapies, in order to evaluate the efficacy of the new therapy regime. These experimental studies have to be performed with a reliable and accurate quantification system, with properties that have been evaluated and where possible flaws have been corrected for. The aim of this work was to evaluate the SPECT pinhole col

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Populärvetenskaplig sammanfattning: Mer än två miljarder människor, mestadels i utvecklingsländer, saknar tillgång till moderna energikällor eller elektricitet. Behovet av rena, effektiva, pålitliga och ekonomiskt överkomliga energitjänster är en viktig fråga i utvecklingsländer, särskilt för landsbygden, där merparten av befolkningen bor. Förnyelsebara energikällor i form av småskaliga vattenkrafOver 2 billion people, mostly in developing countries, have no access to modern fuels or electricity. The necessity of clean, efficient, reliable and affordable energy services is a crucial issue in developing countries, especially in the context of rural areas where the majority of the people lives. Renewable energy sources in shape of small-scale hydropower systems are a complement or alternativ

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Considering the unstable condition of water resources in Iran and many other countries in arid and semi-arid regions, groundwater studies are very important. Therefore, the aim of this study is to model groundwater potential by qanat locations as indicators and ten advanced and soft computing models applied to the Beheshtabad Watershed, Iran. Qanat is a man-made underground construction which gath

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The cost-sharing exemption provided by Art. 132(1)(f) EVD is a provision with a specific objective. The legal function of the provision is to enable economic operators which carry on exempt activities to emancipate certain internal sources which are directly necessary to carry on the exempt activity to be outsourced, and thus supplied exempt. Under the framework of a cost-sharing arrangement, the

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Today plastic packaging is used in a wide array of industries including the pharmaceutical industry. Nevertheless, the increasing amount of plastic waste from packaging is generating great amount of contaminants that do not only damage the environment, but as well the society and the economy as a whole. Whilst industries of fast consumer goods, such as the food and fashion industry enjoy vast rese

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Population ageing affects most European countries, placing increasing pressure on publicly funded Long Term Care (LTC) systems. Informal care is often seen as a low-cost alternative to formal care services, yet it may induce unwelcome reductions in labour supply. This study presents evidence on the relationship of informal care provision, employment probability, and work hours of mature caregivers

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Sierra Leone has struggled with high rates of adolescent pregnancy for some time and reports have shown an increase in these figures during and following the unprecedented Ebola Virus Disease outbreak from 2014 through 15. As young girls are impregnated, it has long been customary for girls to drop out of school. When schools re-opened after the Ebola crisis, this practice was formalized as the Mi

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Industrial design can double up in protected, by copyright protection as well as registered community design protection within EU. Thus, there can be seen a tendency for right holders to take comfort in copyright protection.2 The boundaries between the scope and extensions of the protection forms are not clear, neither to legal professionals nor the industrial professionals. The purpose of the th

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Tensor-valued encoding in diffusion MRI allows probing of microscopic anisotropy in tissue, however, time-dependent diffusion (TDD) can bias results unless b-tensors are carefully tuned to account for TDD. We propose two novel strategies for tuning b-tensors to enable accurate measurements without interference from TDD due to restricted diffusion. The first strategy involves identifying encoding t

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Background: Optimal long-term follow-up (LTFU) care for survivors of childhood, adolescent and young adult (CAYA) cancer can improve or maintain their quality of life by prevention and early treatment of late effects. However, optimal LTFU care is not provided to all CAYA cancer survivors. This systematic review sought to identify associated barriers, facilitators and other factors of LTFU care fo

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Access to outdoor leisure activities is central to supporting active and healthy ageing. To address the lack of research on services supporting continued engagement, this study examines how public, voluntary and private sectors provide outdoor recreation services for older adults. This study uses a qualitative research design to draw on interviews, a workshop, and field observations conducted in a

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The Alternative DSM-5 Model for Personality Disorders (AMPD) consists of level of personality functioning (Criterion A) and maladaptive personality traits (Criterion B). The brief scale versions of these are understudied, while often being used by clinicians and researchers. In this study, we wanted to investigate the overlap and predictive validity of Criterion A and B. Participants (N = 253) wer

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Lake Victoria is Africa’s largest freshwater lake by area shared by three countries: Uganda, Kenya, and Tanzania. The lake supports the economic development of the region through transport and fishing as well as recreational and tourism activities in the three countries. The main ports on the lake are Kisumu, Mwanza, Bukoba, Entebbe, Portbell, and Jinja served by several train ferry services for b

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The Andes of Ecuador are known for an outstanding biodiversity but is also a region where the abandonment rate of agricultural land is high, highlighting the need for forest restoration with native species. Here, the germination and growth requirements for propagation of the hummingbird pollinated bush species Salvia corrugata and Macleania rupestris were studied to better understand their suitabi

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Rivers have been modified significantly during the last 200 years in Switzerland. These modifications were done for protection purposes (protection against floods), construction of hydropower plants, gain of land or other human activities. These artificial transformations have reduced, sometimes drastically, the natural dynamic of the rivers, which has reduced biodiversity, and has also increased

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Strategic University-Industry Collaborations (UICs) are vital for innovation, yet evaluating their multifaceted outcomes presents a significant challenge. This thesis addresses this gap by investigating performance measurement in UICs through an in-depth case study of the long-standing strategic partnership between Tetra Pak and Lund University. By employing a qualitative methodology, incorporatin