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Aims: To analyse dosimetric and clinical predictors for acute and late gastrointestinal toxicity following chemoradiotherapy of anal cancer. Materials and methods: Consecutive patients with locally advanced (T2 ≥4 cm – T4 or N+) anal cancer were selected from an institutional database (n = 114). All received intensity-modulated radiotherapy with concomitant 5-fluorouracil and mitomycin C. Gastroin

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The use of hyperbranched polymers (HBPs) as a processing aid for linear low density polyethylene (LLDPE) was investigated. Various generation (or pseudo-generation) HBPs were used which had either 16 carbon atom alkanes or a mixture of 20/22 carbon atom alkanes on the end groups. In addition, the degree of end group substitution was studied. Blends of up to 10% HBP content were mixed via extrusion

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The “long nineteenth century” in European history, reaching from 1789 to 1914, is a chronological concept introduced by the British historian Eric Hobsbawm. The first part of this long century, described in his book The Age of Revolution, 1790-1848, was marked in the Nordic countries by conflicts between reform-oriented liberal forces and recalcitrant conservatives. This conflict played out politi

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The recent finding of the flea beetle species Podagrica fuscicornis (Linné, 1767) in a commercial market garden at Ystad just off the south coast of Skåne (Scania), the southernmost province of Sweden, is discussed. The species was found in August 2010 residing on plants of Lavatera cashmeriensis (Malvaceae), the follwing years in numbers. Old literature records from Sweden of the species (e.g. Gy

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Miniature hyperspectral and thermal cameras onboard lightweight unmanned aerial vehicles (UAV) bring new opportunities for monitoring land surface variables at unprecedented fine spatial resolution with acceptable accuracy. This research applies hyperspectral and thermal imagery from a drone to quantify upland rice productivity and water use efficiency (WUE) after biochar application in Costa Rica

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Reliable quantification of the sources and sinks of atmospheric carbon dioxide (CO2), including that of their trends and uncertainties, is essential to monitoring the progress in mitigating anthropogenic emissions under the Kyoto Protocol and the Paris Agreement. This study provides a consolidated synthesis of estimates for all anthropogenic and natural sources and sinks of CO2 for the European Un

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Industrial energy efficiency is important for reducing CO2 emissions and could be a competitive advantage for companies because it can reduce costs. However, cost-effective energy efficiency measures are not always implemented because there are barriers inhibiting their implementation. Drivers for energy efficiency could provide means for overcoming these barriers. The aim of this article was to s

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Combustion of fossil diesel is a major environmental problem for both the climate and human health. Renewable diesel fuels have been developed and introduced to the market to reduce the net CO2 emissions. Emission control strategies, such as aftertreatment systems, have been implemented to reduce the health hazardous particulate matter (PM) and nitrogen oxides (NOx) emissions. The overall aim of t

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Familial, sequencing, and genome-wide association studies (GWASs) and genetic correlation analyses have progressively unraveled the shared or pleiotropic germline genetics of breast and ovarian cancer. In this study, we aimed to leverage this shared germline genetics to improve the power of transcriptome-wide association studies (TWASs) to identify candidate breast cancer and ovarian cancer suscep

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Pseudomyxoma Peritonei (PMP) is a rare peritoneal malignancy, most commonly originating from a perforated epithelial tumour of the appendix. Given its rarity, randomized controlled trials on treatment strategies are lacking, nor likely to be performed in the foreseeable future. However, many questions regarding the management of appendiceal tumours, especially when accompanied by PMP, remain unans

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The paper describes a theoretical analysis of programming and what it offers in terms of the meaning-making process. It finds that programming provide opportunity to iterate, to visualise and to perform transductions. Each affordance has been shown to affect the meaning-making process and can enhance it if used in a meaningful way. By using variation theory as a lens of these affordances, we ident

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Compact city planning and development has, over the last 30 years or so, been the hegemonic response to the challenges of sustainable development. Global and local policies promote the compact city model due to the positive outcomes of its design principles and strategics as to achieving sustainable cities in terms of their environmental, economic, and social goals. The aim of this paper is to exa

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Extending the possibilities for health-service consumers to choose among providers has been an important objective on the political agenda in Sweden and elsewhere. Little is known, however, about individual and group preferences concerning the demand for choices. It is often implicitly assumed that individuals can be treated as a group with similar values and demands, but is this true? To what ext

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INTRODUCTION: Using Swedish nationwide registry data, we investigated the contribution of genetic and environmental risk factors to the etiology of smoking status across stages of pregnancy with increasing degrees of social and psychological pressure to reduce or quit smoking, by twin and sibling modeling. AIMS AND METHODS: Smoking status was available before, and during early and late pregnancy f

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Background: Heterogeneity of prostate cancer (PCa) contributes to inaccurate cancer screening and diagnosis, unnecessary biopsies, and overtreatment. We intended to develop non-invasive urine tests for accurate PCa diagnosis to avoid unnecessary biopsies. Methods: Using a machine learning program, we identified a 25-Gene Panel classifier for distinguishing PCa and benign prostate. A non-invasive t

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In this paper we derive the finite-sample distribution of the estimated weights of the tangency portfolio when both the population and the sample covariance matrices are singular. These results are used in the derivation of a statistical test on the weights of the tangency portfolio where the distribution of the test statistic is obtained under both the null and alternative hypotheses. Moreover, w