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Extreme values of non-linear functions of multivariate Gaussian processes are of considerable interest in engineering sciences dealing with the safety of structures. One then seeks the survival probability P{(X1(t),⋯ ,Xn(t))∈ S, all t∈ [0,T]}, where X(t)=(X1(t),⋯ ,Xn(t)) is a stationary, multivariate Gaussian load process, and S is a safe region. In general, the asymptotic survival probability for
This paper presents a novel strategy for aligning patterns created with nano-imprint lithography (NIL) and UV lithography, similar to a mix-and-match process, which allows for the fabrication of large and small features in a single layer of resist. The resin used to demonstrate this new imprinting scheme is SU-8, a very widely used negative photoresist. Rapid stamp manufacturing using ma-N 2405 ph
This paper reports a multi-block unstructured method for incompressible flows and the performance comparison with a multi-block structured method. The unstructured collocated grid is composed of arbitrary cell shapes. Pressure and velocity are stored at cell centres; Rhie and Chow interpolation is used to prevent checker boarding. The SIMPLE algorithm is used for pressure-velocity coupling. The co
We developed a simple one-step dual-label immunoassay for simultaneous measurement of the free, noncomplexed form of prostate-specific antigen (PSA) and total PSA. The assay is based on time-resolved fluorescence and includes a stable fluorescent chelate of Eu to label a monoclonal antibody (mAb) that detects only free PSA, whereas a second mAb labeled with a fluorescent chelate of Tb provides equ
Economic optimization of the production of ethanol by simultaneous saccharification and fermentation (SSF) requires knowledge about the influence of substrate and enzyme concentration on yield and productivity. Although SSF has been investigated extensively, the optimal conditions for SSF of softwoods have yet not been determined. In this study, SO2-impregnated and steam-pretreated spruce was used
Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee,
Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There
This study is based on a total cohort (N = 192) of people born in 1902 and 1903 and living in southern Sweden. Subjects were assessed at baseline when 67 years of age and on eight further occasions over 34 years or until death. The participation rate in the nine examinations ranged from 78-100%. Interviews, psychological tests, and medical examinations were used as well as information on medical d
MAIN QUESTION: To compare the diagnostic properties of Endorette and D&C in women with postmenopausal bleeding, to relate the properties to endometrial thickness as measured by ultrasound, and to assess the women's experiences of the two methods. METHODS: In a prospective study, 133 consecutive women with postmenopausal bleeding were examined with transvaginal ultrasound. After measuring the e
The aim of this work is to generate detailed and simplified kinetic models for the oxidation of the Primary Reference Fuels (PRF) n-heptane, iso-octane and their mixtures, with low numbers of species and reactions. These mechanisms are consistent in terms of the choice of kinetic parameters for the different reaction classes. The further aim is to validate the kinetic models for a wide range of di
This paper reports the implementation of the SIMIND Monte Carlo code on an IBM SP2 distributed memory parallel computer. Basic aspects of running Monte Carlo particle transport calculations on parallel architectures are described. Our parallelization is based on equally partitioning photons among the processors and uses the Message Passing Interface (MPI) library for interprocessor communication a
The Integrated Deposition Model (IDEM) was improved by incorporating a novel multilayer biochemical dry deposition module for gases. The aerosol and base cation deposition module was adopted from IDEM. For evaluation of primary and ecosystem productivity, carbon respiration schemes were included. The resulting Framework for Atmosphere- Canopy Exchange Modelling (FACEM) was then evaluated by the ca
The development of chronic bronchitis (CB) and chronic obstructive airway disease (COAD) seems to be related to inflammatory changes of airway structure. However, the cause and the exact location and type of these changes resulting in altered airway function are not known. Mucosal inflammation is characterized by the recruitment of granulocytes, macrophages and lymphocytes as well as by the sheddi
Buda-Lund hydro-model fits are compared to BRAHMS, PHENIX, PHOBOS and STAR data on identified particle spectra, two-particle Bose-Einstein or HBT correlations, charged particle pseudorapidity distributions and pseudorapidity as well as PT dependent elliptic flow in rootS(NN) = 130 and 200 GeV Au+Au collisions at RHIC. Preliminary results indicate that 7/8 of the particle emitting volume is rather
An intramolecular NEMO potential is presented for the N-formylglycinamide molecule together with an intermolecular potential for the N-formylglycinamide-water system. The intramolecular N-formylglycinamide potential can be used as a building block for the backbone of polypeptides and proteins. Two intramolecular minima have been obtained. One, denoted as C5, is stabilized by a hydrogen bonded five
Children’s target experiences (as recipients of prosocial peer acts and victims of peer aggression) were investigated for their concurrent and longitudinal associations with prosocial and aggressive behavior. Forty-four children (initially 22–40 months) were observed in naturalistic interactions with peers during a two-month period for each of three consecutive years. Results revealed no consisten
RFID (radio frequency identification) technology is developing at a rapid pace. During the last few years, it has been widely discussed in logistics research, as well as in other scientific fields which also approach and contribute to the development of RFID technology. In both logistics and related fields there are findings regarding RFID technology which influence logistics. However, an overall
In man, the predominant proteins in the seminal plasma include semenogelin I, semenogelin II and b-microseminoprotein (MSP). Semenogelin I and II are both synthesized in the seminal vesicles and are the backbone of the gel formed upon semen coagulation. MSP is synthesized in the prostate, but its role has not yet been defined. The genes and cDNA of semenogelin I and II and of MSP were cloned and c
