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A systematic assessment of radiotherapy for cancer was conducted by The Swedish Council on Technology Assessment in Health Care (SBU) and published in 1996. The assessment reviewed the scientific literature up to 1993 on the use of radiotherapy in the treatment of solid tumours. and estimated the costs associated with radiotherapy It also described the current practise of radiotherapy in Sweden 19

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The relationship among CCR5 genotype, cytomegalovirus infection, and disease progression and death was studied among 159 human immunodeficiency virus (HIV)-infected patients with hemophilia. One patient (0.6%) had the CCR5Delta32/CCR5Delta32 genotype (which occurs in similar to2% of the Scandinavian population) and a rapid disease course. His HIV V3 region contained genotypic features attributable

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A search is presented for pair production of a new heavy quark (Q) that decays into aW boson and a light quark (q) in the final state where one W boson decays leptonically (to an electron or muon plus a neutrino) and the other W boson decays hadronically. The analysis is performed using an integrated luminosity of 20.3 fb(-1) of pp collisions at root s = 8 TeV collected by the ATLAS detector at th

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Popular Abstract in Swedish Blodbildande stamceller förekommer i mänsklig benmärg i en frekvens på ca 1/100 000 celler. Med hjälp av cellytemarkörer, t.ex. CD34, kan man rena fram cellpopulationer som är anrikade på stamceller, men det saknas exakt kunskap om hur enskilda stamceller ser ut. De blodbildande stamcellerna har förmåga att vid celldelning antingen förnya sig själva eller att mogna ut. Hematopoietic stem cells (HSCs) have the capacity to maintain hematopoiesis throughout life. HSCs are ideal targets for permanent gene transfer, as the transgene will be expressed in all the progeny of the gene-modified stem cells. The aim of this thesis was to optimize conditions for retroviral gene transfer to human candidate HSCs and to study mechanisms interfering with efficient gene transfer.

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It is commonly assumed that speech production is initiated and guided by clear pre-verbal intentions. These intentions are moreover supposed to function as a standard of accuracy against which actual performance can be measured. Alternative positions to such a centrally governed process have been offered, but very few empirical attempts have been made to explore the issue. We aimed to remedy this

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Popular Abstract in Swedish Denna avhandling är en del av en prospektiv, longitudinell studie, som avser att studera sambandet mellan psykosociala faktorer och debuten och förloppet av barndiabetes. Diabetes är en av de vanligaste kroniska sjukdomarna hos barn i Sverige och antalet insjuknade ökar. Tillsammans med Finland har Sverige en av de högsta förekomsterna av barndiabetes i världen. SjukdomThis thesis is a part of a prospective multi-centre study concerning psychosocial aspects of importance for the onset and course of insulin-dependent diabetes mellitus (IDDM). The investigated population was all children with onset of IDDM in the participating clinics during 1988 and 1989. Of 79 diseased children, 67 participated in the study. To each child a healthy control child was chosen, 61 a

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The effect of a study day on the subject of pain for nurses working at the thorax surgery department The aims of this investigation were: to describe patients' evaluation of pain and the treatment of pain after thorax surgery via sternotomy; to repeat the evaluation with another group of patients following a study day for nurses, featuring pain and pain treatment; and to examine whether the study

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The ATLAS detector at the LHC is used to search for high-mass states, such as heavy charged gauge bosons (W '), decaying to a charged lepton (electron or muon) and a neutrino. Results are presented based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 1.04 fb(-1). No excess above Standard Model expectations is observed. A W ' with S

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Abstract Background: The WHO advises against recumbent or supine position for longer periods during labour and birth and states that caregivers should encourage and support the woman to take the position in which she feels most comfortable. It has been suggested that upright positions may improve childbirth outcomes and reduce the risk for instrumental delivery; however RCTs of interventions to en

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The study describes extraction of extracellular polymeric substances (EPS) from sewage sludge by applying enzymes and enzymes combined with sodium tripolyphosphate (STPP). Additionally, a systematic study of two non-enzymatic extraction agents is described. The assessment of the released products is made by colorimetrical methods and polysaccharides/glycoconjugates identification by the interactio

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Blood coagulation factor IX is composed of discrete domains with an NH2-terminal vitamin K-dependent gamma-carboxyglutamic acid (Gla)-containing region, followed by two domains that are homologous with the epidermal growth factor (EGF) precursor and a COOH-terminal serine protease part. Calcium ions bind to the Gla-containing region and to the NH2-terminal EGF-like domain. To be able to determine

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Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying re

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U–Pb baddeleyite ages demonstrate the presence of three dyke generations within the NW-trending Pará de Minas swarm (São Francisco craton, South America), dated at ca. 1795 Ma (1798 ± 4, 1791 ± 7 and 1793 ± 18 Ma), ca. 1710 Ma (1702 ± 13 and 1717 ± 11 Ma) and 766 ± 36 Ma. These ages have implications for the São Francisco-Congo (SF-Congo) craton within the Rodinia and Columbia supercontinent confi

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The volcanic Hartley Formation (part of the Olifantshoek Supergroup, which is dominated by red bed successions) in South Africa recorded depositional and tectonic conditions along the western Kaapvaal Craton during the late Palaeoproterozoic. It formed in association with red bed deposition elsewhere in the cratonic hinterland and along the craton’s northern margin. However, the exact correlation

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The paper examines the relationship between non-formal education activities and youth employability in the Republic of Armenia. A case study has been conducted in order to identify soft skills competitive in the labour market and see to what extent non-formal education increases youth productivity thus helping them get engaged in the job market. Another thing that the paper aims to study is the ro

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Unsafe abortion is a major contributing factor to maternal mortality with 47,000 largely avoidable deaths occurring globally every year, the majority in the global south. Ethiopia has taken a unique approach to addressing maternal mortality impacted by unsafe abortion through a 2005 reform of the abortion legislation in which abortion is illegal but available under a range of exceptions. The purpo