Filtyp
Maternal alloantibody-induced hemolytic disease of the fetus and newborn (HDFN) remains a significant concern worldwide. Alloimmune HDFN can be pathogenetically named by the specific alloantibodies involved. Moreover, four mechanistic pathway types are generally recognized in clinical practice: classical or extravascular hemolysis; immune-pressure-escaped, also known as antibody-mediated antigen-m
Horizontal gene transfer (HGT) is a major driver of evolution and a key source of innovation in the microbial world. Mobile genetic elements (MGEs), such as plasmids and phages, often act as agents of HGT or as vehicles for cargo genes, some of which define the adaptive potential of the host organism in specific environments. These genes are involved in immunity, anti-immunity, virulence, and anti
Light chain monoclonal gammopathy of undetermined significance (LC-MGUS) is an asymptomatic precursor of multiple myeloma (MM) and related disorders defined by abnormal free light chain (FLC) testing. Recently, revised FLC reference intervals were proposed by the iStopMM study group. We evaluated their performance in a large population-based cohort. MGUS cases were identified from the Danish Lymph
Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin-dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's characteristics. Glucuronidases (EC 3.2.1.139) and xylan α-1,2-gl
We explore mental health as a potential mechanism to explain the labor market penalty of an early-onset physical disability using administrative data from Sweden. For methodological reasons, we focus on persons with Cerebral Palsy (CP) and use prescriptions for mental health conditions. We examine how much of the differences in labor market outcomes is explained by prescriptions for mental health
Thermal energy storage is likely to be integral to a sustainable, secure and affordable energy system facing ever greater challenges in matching supply and demand. Techno-economic studies have explored the potential for thermal storage deployment, but transitions in the energy system are also influenced by the activities and decisions of an array of actors. We gathered new empirical evidence from
The objective of this study is to analyze whether the trend towards operating on patients with less severe primary hyperparathyroidism (pHPT) than earlier is reflected in a change of preoperative presentation and surgical outcome.
Background: Little is known about the development of excess skin and requests for body-contouring surgery after bariatric surgery in adolescents. Methods: Forty-seven of 86 adolescents that had undergone gastric bypass surgery answered two questionnaires regarding excess skin and requests for and performed body-contouring surgery. An objective assessment of the amount of excess skin was also perfo
The problem of optimum load control of steam power plants has been dealt within many technical papers during the last decades. Deregulation of the power markets and close to the (bio-) fuel source thinking has lead to a trend of small scale combined heat and power plants. These plants are usually operated according to the heat demand and therefore they spend a significant time on partial load. The
Sub-cell-fix re-initialization method was proposed by Russo and Smereka (J. Comput. Phys. 2000; 163: 51-67) as a modification to the re-distancing, algorithm Of Sussman et al. (J. Comput. Phys. 1994; 114: 146-159) that determines the distance function from an interface known as the zero level-set. The principal goal of sub-cell-fix method is to compute the distance function of the cells adjacent t
Abstract in UndeterminedFew studies have investigated long-term odor recognition memory, although some early observations suggested that the forgetting rate of olfactory representations is slower than for other sensory modalities. This study investigated recognition memory across 64 days for high and low familiar odors and faces. Memory was assessed in 83 young participants at 4 occasions; immedia
We employ the optimal orthogonal portfolio approach to investigate if the size and book-to-market effects in US data are related to risk factors beside the market risk. This method enables us to estimate the upper limit of the risk premium, due to observed as well as all possible unobserved factors, which can be derived from a linear asset pricing model. As a corollary, it is possible to divide th
This paper presents a maximum likelihood based approach to data fusion for electromagnetic (EM) and electrical resistive (ER) tomography. The statistical maximum likelihood criterion is closely linked to the additive Fisher information measure, and it facilitates an appropriate weighting of the measurement data which can be useful with multi-physics inverse problems. The Fisher information is part
The aim of this study was to evaluate the suitability of in vivo x-ray dark-field radiography for early-stage diagnosis of pulmonary emphysema in mice. Furthermore, we aimed to analyze how the dark-field signal correlates with morphological changes of lung architecture at distinct stages of emphysema.
Decrease of the human brain temperature was induced by intranasal cooling. The main purpose of this study was to compare the two magnetic resonance methods for monitoring brain temperature changes during cooling: phase-difference and magnetic resonance spectroscopic imaging (MRSI) with high spatial resolution. Ten healthy volunteers were measured. Selective brain cooling was performed through nasa
Although not yet widely implemented, fraction of exhaled nitric oxide (FeNO) has emerged in recent years as a potentially useful biomarker for the assessment of airway inflammation both in undiagnosed patients with non-specific respiratory symptoms and in those with established airway disease. Research to date essentially suggests that FeNO measurement facilitates the identification of patients ex
