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Nuklearmedicinsk bildtagning med hjälp av radiofarmaka är ett viktigt verktyg för att studera biologiska processer och humansjukdomar. Bildtagning sker ofta med en detektor i kombination med en kollimator. En typ av kollimering är pinnhålskollimering, där ett pinnhål i ett opakt material placeras mellan en källa och en detektor. Pinnhålet fyller samma funktion som en optisk lins då emitterade fotoThe focus of this dissertation is the use of pinhole collimation in Nuclear Medicine. A pinhole is a single aperture in an opaque material that is placed between the detector and source of interest, and photons must pass through the hole to reach the detector. The choices of pinhole parameters, e.g. the pinhole material and size of the opening, are closely linked to the performance of the detector

This article seeks to explain what policy approaches and policy measures are best suited for promoting new regional industrial path development and what needs and possibilities there are for such policy to change and adapt to new conditions in order to remain efficient. The article departs from the notion of Smart Specialization and discusses how regional strategies that are inspired by this appro

A methodology for designing and scaling the performance and thermal characteristics of electric powertrain components is presented. This methodology is aimed at finding optimum component combinations based on a set of requirements. Both drive-cycle performance and specific operating modes such as curb-climbing and maximum wheel speed are considered. This allows the selection of electrical machine

Human intrahepatic lymphocytes are enriched in CD1d-unrestricted T cells coexpressing NKR. Although the origin of this population remains controversial, it is possible to speculate that the hepatic microenvironment, namely epithelial cells or the cytokine milieu, may play a role in its shaping. IL-15 is constitutively expressed in the liver and has a key role in activation and survival of innate a

A search for the decays of the Higgs and Z bosons to J/psi gamma and Upsilon(nS)gamma (n = 1,2,3) is performed with pp collision data samples corresponding to integrated luminosities of up to 20.3 fb(-1) collected at root s = 8 TeV with the ATLAS detector at the CERN Large Hadron Collider. No significant excess of events is observed above expected backgrounds and 95% C.L. upper limits are placed o

A description of general models for adsorption kinetics is given. Combinations of the models are compared with adsorption data for the self-associating proteins β-lactoglobulin A and B, from Elofssonet al.(U. M. Elofsson, M. A. Paulsson, and T. Arnebrant,Langmuir,submitted). The adsorption onto methylated silica surfaces was measured by these authors by ellipsometry in phosphate buffer (0.01M,pH 7

The purpose of this study was to perform an initial investigation of the possibility to determine breast cancer growth rate with 14C bomb-pulse dating. Tissues from 11 breast cancers, diagnosed in 1983, were retrieved from a regional biobank. The estimated average age of the majority of the samples overlapped the year of collection (1983) within 3σ. Thus, this first study of tumour tissue has not

Representation of atmospheric transport is a major source of error in the estimation of greenhouse gas sources and sinks by inverse modelling. Here we assess the impact on trace gas mole fractions of the new physical parameterizations recently implemented in the atmospheric global climate model LMDz to improve vertical diffusion, mesoscale mixing by thermal plumes in the planetary boundary layer (

The aminopropyltransferase spermidine synthase (SpdS) is a promising drug target in cancer and in protozoan diseases including malaria. Plasmodium falciparum SpdS (PfSpdS) transfers the aminopropyl group of decarboxylated S-adenosylmethionine (dcAdoMet) to putrescine or to spermidine to form spermidine or spermine, respectively. In an effort to understand why efficient inhibitors of PfSpdS have be

Human pluripotent stem cells provide new choices for sources of A9-type dopaminergic (DA) neurons in clinical trials of neural transplantation for patients with Parkinson's disease (PD). For example, "self" and HLA-matched A9 DA neurons may improve the patient-to-patient variability observed in previous clinical trials using fetal DA neurons and obviate the need for long-term immunosuppression in

Temperature limitations of Solid Oxide Fuel Cells (SOFC) in transient single operation and steady-state Hybrid System (HS) operation with Gas Turbines (GT) are presented. For transient SOFC simulations, an unsteady-state SOFC model was developed by upgrading a detailed validated steady-state model. As critical SOFC single operation modes, concerning the risk of material cracking due to exceeding S

Popular Abstract in Swedish Allteftersom kraven på kvalité och prestanda hos dagens produkter ökar används alltmer avancerade material som en del av modern produktion. Problemet som uppstår är dock att dessa material ställer nya krav på tillverkningsprocessen och då inte minst vid skärande bearbetning. Trots att en betydande mängd forskning redan har publicerats vad gäller skärande bearbetning av As quality and performance demands on today’s products increases, more and more advanced materials are being used during modern production. The problem is however that this in turn place new demands on the machining processes utilized. Even though a significant amount of research has been published on the machining of these materials knowledge is still limited in several crucial areas. A problem w

Desalination can be a cost-effective way to produce fresh water and possibly electricity. The Gaza Strip has had a complex hydro-political situation for many years. Gaza is bordered by the Mediterranean in the west, by Israel in the north and east and by Egypt in the south. Water and electricity consumption in the Gaza Strip is expected to increase in the future due to the increasing population.

Popular Abstract in Swedish Transplantation av nervvävnad till hjärnan är inte en ny idé. Redan 1890, publiserade Thompson de första försöken att transplantera vuxen hjärnvävnad till det vuxna centrala nervsystemet och han rapporterade att vävnaden överlevde i sju veckor "without wholly losing its identity". Trots detta var det först under 1970-talet som metoderna för intracerebral nervcellstranspIntracerebral neuronal transplantation have been shown to ameliorate symptoms of brain dysfunction in both animals models and Parkinson's disease, although problems still remain. The newly introduced technique of ex vivo gene transfer could serve as an alternative approach, possible avoiding some of the draw-backs of the embryonal tissue used in neuronal grafting. We have investigated the feasibli

Manufacturing is an industry in which the effects of globalization are obvious. Manufacturing costs are a key factor in this respect and affect, for example, decisions about offshoring, i.e., moving production abroad. If Sweden and other Western countries are to maintain large manufacturing sectors, they must be competitive, making cost one of the most critical parameters. The work presented here

Borderline Personality Disorder (BPD) has largely been associated with self-harm and chronic suicidality, despite the fact that these behaviours comprise only one diagnostic criterion. Treatments for self-harm are mostly indicated for individuals with BPD. Emerging literature suggests that youth with histories of depression are at risk of both self-harm and completed suicide. For individuals with