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Changes in ligand binding to adrenoceptors ([3H]prazosin to α1-receptors, [3H]idazoxan to α2-receptors and [125I]cyanopindolol to β-receptors) following transient cerebral ischemia were investigated using autoradiographic methods. The binding was quantified in brain sections from control rats, rats subjected to 15 min of 2-vessel occlusion ischemia, and rats with recirculation times of 1 h, 1 week
Året är 2053 och den svenska regeringen har just invigt museet FOSSIL och dess första utställning ’Carbon Ruins’. År 2045 uppnådde Sverige nettonollutsläpp av växthusgaser, och blev därmed det första landet i världen att lämna den fossila tidsåldern (1849 - 2049). Två hundra år som förde med sig en otrolig välståndsökning, men också oljerelaterade konflikter och en klimatkatastrof som allvarligt hIt is 2053. The Swedish government has just opened its landmark museum FOSSIL with its first exhibition Carbon Ruins. The exhibition and its grand opening is a celebration of the fact that global net-zero emissions of carbon dioxide were reached in 2050. Sweden, in line with its 2017 targets, reached net-zero emissions of greenhouse gases already in 2045, being the first country in the world to st
This paper addresses the influence of deteriorating structural system characteristics on the value of structural health monitoring (SHM) before its implementation. The value of SHM is calculated within a recently developed framework utilizing the Bayesian pre-posterior decision analysis modelling the structural system performance, the integrity management, the structural risks and the SHM informat
Syftet med forskningen som presenteras i denna avhandling är att vidareutveckla tillgänglighetsområdet i riktning mot en större perspektivrikedom. Avhandlingen baseras på kulturhistorisk aktivitetsteori (CHAT). Den analyserar en systemisk helhet utifrån sådana mänskliga, artefaktuella och naturliga faktorer som påverkar en individs handlingsmöjligheter i konkreta situationer.Avhandlingen har två h
Alveolar epithelial cells (AEC) have been implicated in pathological remodelling. We examined the capacity of AEC to produce extracellular matrix (ECM) and thereby directly contribute towards remodelling in chronic lung diseases. Cryopreserved type 2 AEC (AEC2) from healthy lungs and chronic obstructive pulmonary disease (COPD) afflicted lungs were cultured in decellularized healthy human lung sli
Background: In this paper, we share our experiences of using ‘photovoice’ methodology as a way to generate data in intensive care units concerning the place and space of care. We have adapted and modified ‘photovoice’ in researching people's lived experiences of ICU. Researching lived experiences in an intensive care context is challenging because of the complex nature of critical care. Aim: This
BackgroundThe Dyspnoea-12 (D12) and Multidimensional dyspnea profile (MDP) are commonly used instruments for assessing multiple dimensions of breathlessness but have not been validated in older people in the population. The aim of this study was to validate the D12 and MDP in 73-years old men in terms of the instruments’ underlying factor structures, internal consistency, and validity.MethodsA pos
Aim: The aim of the study was to deepen the current knowledge of how patients with chronic obstructive pulmonary disease and long-term oxygen treatment think about and expect end-of-life. Design: A qualitative design was used. Methods: A purposeful sample of 19 patients with oxygen-dependent chronic obstructive pulmonary disease was obtained from the Swedish National Registry on Respiratory Failur
When a course is designed, it is common to do it for a typical group of students, considered to represent “the majority”, the “norm” or the “average”. The concept of “edges” challenges this view: given the multiple dimensions that teaching and learning encompass, there will always be students who do not belong to a norm and will end up on an edge if they are not included in the course design. In t
Microbicides in the leather industries are employed to avoid the biodeterioration of the hides by microorganisms. This problem may lead to harmful characteristics to the end product such as stains, roughness and decrease mechanical properties of leather. Therefore, microbicides like the 2-(thiocyanomethylthio) benzothiazole (TMCTB) are applied in distinct steps of the tanning process as alternativ
The main purpose of this brief reflection is to examine the relationship between (a) Muslim communal values of neighborliness, mutual support and responsibility for those living together in a defined, spacial community and b)the built environment and structures of mosques and community gathering spaces, with a focus on how the existence of such a built environment and infrastructure helps to devel
Regeringen presenterade 2024 ett resultat av en utredning som utrett huruvida ett förbud mot äktenskap mellan kusiner och vissa andra släktskap bör införas. Utredningen utmynnade i ett lagförslag om att det bör införas ett förbud mot kusinäktenskap utan möjlighet till dispens. Det är ännu inte fast- ställt huruvida detta lagförslag kommer att träda i kraft, men detta skulle inte vara Sveriges försIn 2024, the government presented the result of a ministry report series that aimed to investigate whether a ban on marriage between cousins and other relatives should be implemented. The investigation resulted in a legislative proposal that Sweden should introduce a ban on cousin marriage without the possibility of dispensation. It is not yet determined whether this bill will come into effect, bu
Den svenska djurskyddslagstiftningen slår fast att djur har en rad olika in- tressen och behov som ska beredas skydd. Samtidigt har djur i alla tider be- traktats som objekt i rättslig mening och har till skillnad från rättssubjekt inte kunnat inneha intressen och rättigheter. Den här uppsatsen undersöker hur sagda ordning växt fram genom historien och vilka implikationer den har för hur djurskyddThe Swedish animal welfare legislation states that animals have interests and needs that must be protected. However, throughout history, animals have been regarded as objects in legal terms, lacking the capacity to hold in- terests and rights. This essay explores the historical development of said or- der and its implications for how animal welfare interests are represented in Swedish administrati
Bestämmelsen om uppehållstillstånd på grund av synnerligen ömmande omständigheter infördes i den nya utlänningslagen 2005. Enligt bestämmelsen kan en utlänning beviljas uppehållstillstånd om det föreligger synnerligen ömmande omständigheter och vid bedömningen ska särskild hänsyn tas till utlänningens hälsotillstånd, anpassning till Sverige och situationen i hemlandet. I den nya bestämmelsen förde
