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A translocation between chromosomes 9 and 22 produces the fusion gene BCR-ABL that leads to the constitutive activity of a tyrosine kinase. This initiates the uncontrolled proliferation of myeloid cells causing Chronic Myeloid Leukaemia (CML). The disorder is treated by tyrosine kinase inhibitors (TKIs) that prevent the progression of CML into more advanced phases. The treatment must be sustained
The case company under study has conducted a continuous process of business model innovation for sustainability since 2007, but is suffering from barriers present in the process. The limited amount of literature on business model innovation for sustainability provides little guidance on barriers. Therefore, this research aims to contribute to the literature by identifying what barriers are present
This thesis explores the European Commission’s proposal on General Reverse Charge Mechanism. VAT is a final tax on consumption. It is imposed on every transaction in the supply chain with the general aim of being deductible and thus being neutral for businesses with the right to deduct. The initial aim of the VAT system was to operate as if all the transactions occurred in one single country; howe
The purpose of this study is to explore the opportunities and challenges for self-employed artists who use social media for their business. The research is focused on painters and illustrators who have digitalised and commercialised their own artwork. The method follows a qualitative research framework with a comparative design of multiple cases on the level of individual artists. Seven artists fr
Purpose: The purpose of this study was two-fold. First, we aimed to develop a framework concerning how to directly and indirectly control discrimination in the workplace using Man- agement Control Systems (MCS). Second, we wanted to examine whether this framework is practically applicable in multinational enterprises (MNE). Methodology: The first part of the purpose was achieved through conduc
The invention of the integrated circuit is a key milestone in the history of electronic circuits. Since its introduction the number of components on a chip have increased rapidly, making them more powerful and able to perform complex operations, but it has also changed the design process. Today different parts of a chip can be developed separately as Intellectual Property (IP) and then put togethe
Urbanisation is an inevitable part of globalisation. With the globalised food chain in place to feed the growing number of people living in urban areas. A remedy is often expressed to be urban farming, with local, sustainable production of food. This study presents a preliminary assessment of the dynamics between urban farms and residents in Malmö. Urban farms produce available food for the reside
Hydrogenation is a universal reaction, which is widely used in industry and academy. However, the reaction is not easy to be studied in extreme conditions such as high temperature and high pressure. On top of that, using Raman spectroscopy to observe the reaction is not so customary. Due to these aspects, the experiment was carried out. During the working process, the degradation reaction was also
In mathematical education it is crucial to have a good teaching plan and to execute it correctly. In particular, this is true in the field of numerical analysis. Every teacher has a different style of teaching. This thesis studies how the basic material of a particular topic in numerical analysis was developed in four different textbooks. We compare and evaluate this process in order to achieve a
Saltmarshes are areas of coastal grassland that are regularly flooded by seawater. They support a large number of resident and migratory bird species, both overwintering and breeding. The Mersey Estuary Site of Special Scientific Interest (SSSI) is situated in North West England and it supports nationally significant numbers of overwintering wildfowl and waders. Decline of three overwintering bird
Purpose: The purpose of this study is trying to understand which elements are essential to obtain loyalty in the alcoholic beverage industry and how companies can focus their branding efforts on these drivers of loyalty. Methodology: A literature review is conducted to identify the key drivers which can influence brand loyalty. These drivers are then analysed by researching two case studies, Hein
Sverige har historiskt sett haft ett generöst konsolideringssystem för koncerner med stora avdragsmöjligheter. Avdragsmöjligheten för bland annat ränta har dock begränsats i allt större utsträckning på grund av viktigare samhällsintressen, så som ett förhindrande av skatteflykt och aggressiv skatteplanering. Ett resultat av detta är att det år 2019 trädde i kraft nya generella ränteavdragsbegränPreviously Sweden has had a generous consolidation system for groups with large deduction possibilities. However, the possibility of interest deductions, among other things, has increasingly been limited due to more important societal interests, such as preventing tax evasion and tax avoidance practices. As a result, new general interest limitation rules were put into practice in 2019 affecting
This thesis examines how sustainability is prioritised politically and integrated in the Danish municipal primary and lower secondary education. It consults representatives from the Ministry of Education, the unicipality of Copenhagen and ten lower secondary education teachers about their perceptions of sustainability and education and their experiences with integration of sustainability education
This thesis describes attempts at estimating the uncertainty of the 2-metre temperature forecast error from a probabilistic point of view, utilizing Bayesian neural networks. Bayesian neural networks are a type of machine-learning algorithms used to find patterns in data and make probabilistic predictions. Multiple fields of output data from the ECMWF IFS global model, along with temperature measu
This paper analyses the economic impact of Transnational Corporations through their activities across Global Value Chains (GVCs), using Mexico as baseline country. By exploiting the UNCTAD-Eora Global Value Chain database, we conduct an exploratory research methodology. We first unfold the relationship between GVC trade and economic development by disaggregating GVC trade into its two components (
The Standard Model of particle physics (SM) attempts to describe the fundamental particles and how they interact with each other. This model is however incomplete, as shown by various experimental observations. ATLAS is one of the experiments currently in operation at the Large Hadron Collider, which aims to search for new physics beyond the SM. To perform these searches, many ATLAS analyses look
This paper compares the explanation for social change that are offered by three theories of rape, all of which apply a socio-cultural and a gender perspective.
Stakeholders’ participation has been recognized as a pillar for a transition toward a more sustainable society. However, there is little empirical evidence concerning the viability of participation mechanisms at large scale. This research analyzes a popular referendum process in Switzerland against a law that would have been a step toward a low-carbon society in the Canton of Fribourg. Aiming to i
Attention to the role of religious NGOs (RNGOs) in international arenas has grown in the past decade. This study explored the role of values in the policies of RNGOs involved in humanitarian aid. It sought to compare the values of RNGOs with varying levels of involvement with the Steering Committee for Humanitarian Response (SCHR) in order to determine if values may be an issue inhibiting cooperat
