Filtyp
The Damages Directive has been celebrated as a milestone for the private enforcement of EU competition law. The Directive harmonises national procedural laws and aims to facilitate full compensation for damages occurred as a result of competition law violations. At the same time, US and EU businesses more frequently use contractual clauses that might present obstacles in obtaining compensation. Re
Aim: Kynurenine metabolites are potential modulators of psychiatric disease. We aimed to develop a highly sensitive biochemical analysis of cerebrospinal fluid (CSF) tryptophan (TRP) metabolites, to investigate the stability of metabolites and to confirm our previous findings of aberrant CSF quinolinic acid (QUIN) and picolinic acid (PIC) in suicide attempters using this method. Methodology &
In this study, Spatial Multi-Criteria Evaluation and the least cost path analysis were applied to find the optimal by-pass road alignment in the Tlokweng Planning Area in Botswana. One-At-a-Time sensitivity analysis and the statistical test for zero proportion were used to investigate the robustness of the entire model. Four alternative by-pass roads were produced stressing economic, environmental
In this paper we provide a counterpoint to conventional views on integrative reviews in knowledge development, as exemplified by Elsbach and Van Knippenberg (2020). First, we critique their proposed integrative review by identifying and problematizing several key assumptions underlying it, particularly their idea that the integrative review can simply build on existing studies and lead the way to
Objective: To develop and externally validate prediction models for incident hand osteoarthritis (OA) in a large population-based cohort of middle aged and older men and women. Design: We included 17,153 men and 18,682 women from a population-based cohort, aged 35–70 years at baseline (1995–1997). Incident hand OA were obtained from diagnostic codes in the Norwegian National Patient Register (1995
Background: Optimal alignment is of utmost importance when treating pediatric patients with craniospinal irradiation (CSI), especially with regards to field junctions and multiple isocenters and techniques applying high dose gradients. Here, we investigated the setup errors and uncertainties for pediatric CSI using different setup verification protocols. Methods: A total of 38 pediatric patients t
Autologous hematopoietic stem cell transplantation (AHSCT) to treat multiple sclerosis (MS) has mostly been used in devastating cases as the last option to stop further neurological deterioration. However, evidence from several retrospective clinical trials indicates that young, less disabled patients with highly inflammatory active MS are the most likely to benefit from AHSCT, and after moving fr
We present a program to compute polarizabilities of nominal one-electron systems using the Lagrange-mesh method (LMM) (Baye, 2015), that was used by Filippin et al., (2018). A semiempirical-core-potential approach is implemented, ultimately solving a Dirac-like equation by diagonalizing the corresponding Hamiltonian matrix. In order to build the core potential, the core orbitals are obtained from
In recent years, quantitative approaches based on mathematical theories and ICT tools, known under the terms of digital, computational, and virtual archaeology, are more and more involved in the traditional archaeological research. In this paper, we apply shape analysis techniques to 3D digital replicas of archaeological findings to support their interpretation. In particular, our study focuses on
Prostate cancer is the second most common cause of cancer-related deaths in men, representing a major source of morbidity and mortality. Androgen deprivation therapy is the primary treatment for patients with advanced prostate cancer at disease presentation, which can be achieved either with surgical or chemical castration. The development of gonadotropin-releasing hormone agonists revolutionized
Background: Previous research shows that critical constructive feedback, that scaffolds students to improve on tasks, often remains untapped. The paper’s aim is to illuminate at what stages students provided with such feedback drop out of feedback processing. Methods: In our model, students can drop out at any of five stages of feedback processing: (1) noticing, (2) decoding, (3) making sense, (4)
Background: Depressive symptoms are common in rheumatic diseases and influence patients’ quality of life. The Patient Health Questionnaire-9 (PHQ-9), which assesses symptoms of depression, is valid in English in patients with systemic sclerosis (SSc). However, the measurement properties of the PHQ-8 (short version of the PHQ-9) have not been evaluated in Swedish patients with SSc. Objective: To in
We present an approach for the estimation of ore processing residue volumes in historical mine waste dumps by the use of different geophysical methods in combination with mineralogical investigations. The stamp mill dump in the Harz mountains, Germany was examined with the methods electrical resistivity tomography (ERT), ground penetrating radar (GPR) and spectral induced polarization (SIP) flanke
HIPPIE is a soft X-ray beamline on the 3 GeV electron storage ring of the MAX IV Laboratory, equipped with a novel ambient-pressure X-ray photoelectron spectroscopy (APXPS) instrument. The endstation is dedicated to performing in situ and operando X-ray photoelectron spectroscopy experiments in the presence of a controlled gaseous atmosphere at pressures up to 30 mbar [1 mbar = 100 Pa] as well as
RQ20 (Research Quality Evaluation 2020), the major research quality evaluation at Lund University, is part of a cycle of assessments done in the last two decades. RQ20 differs from the former evaluations in that it assesses the preconditions for research quality and the potential areas of elevation in all parts of the University, rather than being an evaluation of research quality. The many dimens
Yangia sp. ND199 is a moderately halophilic bacterium isolated from mangrove samples in Northern Vietnam, which was earlier reported to grow on several sugars and glycerol to accumulate poly(hydroxyalkanoates) (PHA). In this study, the potential of the bacterium for co-production of exopolysaccharides (EPS) and PHA was investigated. Genome sequence analysis of the closely related Yangia sp. CCB-M3
