Filtyp
Background: Obstetrical anal sphincter injuries are complications of vaginal birth that have the potential to cause substantial maternal morbidity. Predicting these injuries might help to improve maternal care as well as antenatal counseling and patient education. Previous attempts to create prediction models have in many cases involved variables only known postpartum, which limits their use in an
Stormwater management is essential for preventing urban flooding and protecting water quality in receiving bodies. Traditionally viewed as a nuisance, stormwater is now being re-evaluated as an alternative resource for non-potable uses such as toilet flushing and irrigation through rainwater harvesting systems (RWHS). Within the European Union's Horizon 2020 project REWAISE, pilot studies with cer
Alternative food initiatives are vital for transforming food systems towards sustainability by challenging, replacing, and complementing the status quo. Understanding how these initiatives contribute to transformation requires attention not only to their intended outcomes but also to the processes through which these outcomes contribute to broader social change. Existing assessment frameworks rare
COVID-19 convalescent plasma (CCP) obtained from recently recovered people is safe and effective against SARS-CoV-2. Currently available CCP is a “hybrid” product with antibodies from individuals who had both infection and vaccination (vaccine-boosted CCP). B-cell depleted patients are at risk of not producing antibodies after either infection or vaccination, hence conceivably among those who woul
This paper explores the challenges and barriers of forced migrants at the nexus of housing and social integration, presenting the outcomes of an international and interdisciplinary collaboration funded by the JPI Urban Europe programme. Research includes the case study cities Leipzig, Lund, Riga, and Vienna, utilizing primary and secondary data in a transdisciplinary process involving theoretical
For circular retail models to successfully replace linear consumption in the future, retailers must understand the lived reality of second-hand customer journeys. However, existing customer journey mapping methods often fail to capture the non-linear, phygital, and multi-retailer nature of such journeys. This article introduces ‘messy customer journey self-mapping’, a novel qualitative method desi
Chagas disease (CD), caused by Trypanosoma cruzi, is a neglected tropical illness affecting 6-8 million people in Latin America. Reaching scholarly consensus on the host response to T. cruzi infection remains a significant challenge, primarily due to substantial heterogeneity in outcomes driven by both the choice of animal model and the infecting parasite's discrete typing unit (DTU). This var
The purpose of this narrative review is to provide an evidence-based update on management strategies for young adults with meniscal tears, based on two recent randomized controlled trials comparing a surgical vs. non-surgical treatment strategy for this patient group. The results from these trials suggests that exercise therapy is a viable treatment alternative for young adults with a meniscal tea
As immersive technologies expand in education, a gap persists between teachers’ familiarity with virtual reality (VR) tools and effective pedagogical use. This study designed, implemented, and evaluated a 60-h VR Trainer Training Program using Educational Design Research (EDR) and the Taba-Tyler curriculum model. Sixteen teachers participated in a needs analysis, followed by 42 in-service teachers
Rates of cognitive decline in Alzheimer’s disease (AD) are extremely heterogeneous. Although biomarkers for amyloid-beta (Aβ) and tau proteins, the hallmark AD pathologies, have improved pathology-based diagnosis, they explain only 20–40% of the variance in AD-related cognitive impairment (CI). To discover novel biomarkers of CI in AD, we performed cerebrospinal fluid (CSF) proteomics on 3,397 ind
Introduction: Excessive worry is common during adolescence and across a range of psychiatric conditions. There is a growing evidence base for the efficacy of cognitive behaviour therapy (CBT) in reducing the frequency of excessive worrying as a primary outcome in the context of clinical trials of youth with generalized anxiety disorder, and as a secondary outcome in trials of CBT for youth with ob
Psychological distress, including depression, anxiety, and stress, requires time-efficient assessment tools suited for digital and momentary settings. The Screening Tool for Psychological Distress (STOP-D) is a five-item scale developed for brief mental health screening, but it has not yet been validated in Swedish. This study aimed to evaluate the psychometric properties and diagnostic accuracy o
Accurate grading of Oil Palm Fresh Fruit Bunches (FFB) is pivotal for maximizing agricultural yield, yet manual assessment in unstructured environments remains labor-intensive and subjective. While Convolutional Neural Networks (CNNs) offer an automated solution, the conventional strategy of scaling network depth often yields diminishing returns or overfitting on moderately sized datasets. To over
Background: Standardized care pathway (SCP) for macrohematuria (patients aged ≥50 years) in Sweden includes four-phase computed tomography urography (CTU) before cystoscopy, but targeted SCP lead time for CTU (6 days)/treatment is fulfilled in <25% of patients. Purpose: To retrospectively analyze the incidence of CTU-diagnosed upper urinary tract (UUT), kidney and bladder tumors, calculi, radiatio
Preconception health status, especially of women, but also of men, is known to influence pregnancy outcomes. Despite knowledge of the growing importance of preconception health, numerous challenges remain for conducting research in this population and delivering appropriate clinical care. The 2023 Global Pregnancy Collaboration annual workshop focused on exploring preconception health as it relate
BACKGROUND: Transportation noise increases the risk of ischemic heart disease (IHD), but few studies have investigated subtypes of IHD, such as myocardial infarction (MI), angina pectoris, or heart failure. We aimed to study whether exposure to road, railway and aircraft noise increased risk for ischemic heart disease (IHD), IHD subtypes, and heart failure in the entire adult Danish population, in
BACKGROUND: Epidemiological studies have linked transportation noise and cardiovascular diseases, however, atrial fibrillation (AF) has received limited attention. We aimed to investigate the association between transportation noise and AF risk.METHODS: Over the period 1990-2017 we estimated road and railway noise (Lden) at the most and least exposed façades for all residential addresses across De
BackgroundPathogenic germline variants (PGVs) in certain genes are linked to higher lifetime risk of developing breast cancer and can influence preventive surgery decisions and therapy choices. Public health programs offer genetic screening based on criteria designed to assess personal risk and identify individuals more likely to carry PGVs, dividing patients into screened and non-screened groups.
