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Compact in-memory computing architectures are desirable to embed artificial intelligence (AI) in resource-restricted edge devices. However, current technologies face limitations in both the area and energy efficiency. Here, a reconfigurable ferroelectric tunnel field-effect transistor (ferro-TFET) is presented that can be used as an ultra-scaled cell for low-power in-memory data processing. A gate
Many important problems involving a group of unmanned ground vehicles (UGVs) are closely related to the multi traviling salesman problem (m-TSP). This paper comprises a comparative study of a number of algorithms proposed in the litterature to solve m-TSPs occuring in robotics. The investigated algoritms include two mixed integer linear programming (MILP) formulations, a market based approach (MA)
The paper introduces a new device for analyzing, teaching, and training jaw movements: the MARRYS helmet. We outline the motivation for the development of the helmet, describe its key advantages and features relative to those of the Electromagnetic Articulograph (EMA) and illustrate by means of selected study portraits the possible uses of the MARRYS helmet in the various fields of the empirical a
A computer-assisted language learning software for mobile devices (MAC) is presented, that was aimed to helping speakers acquire speech contrasts not native to their own language. The software is based on the high variability phonetic training (HVPT) technique. An overview of the software is given, followed by results from an efficacy study. Two groups using slightly different variations of the MA
This paper forms part of a broader study on the design and optimisation of a high speed switched reluctance motor (SRM) for hybrid-electrical automotive traction applications. The main focus of this particular paper is to explain the design optimisation methodology followed. Furthermore, the main aim of the motor design is to push the power density of the SRM as high as possible. This leads to num
In this paper, we introduce a randomized version of the backward Euler method that is applicable to stiff ordinary differential equations and nonlinear evolution equations with time-irregular coefficients. In the finite-dimensional case, we consider Carathéodory-type functions satisfying a one-sided Lipschitz condition. After investigating the well-posedness and the stability properties of the ran
Immersive virtual reality (VR) has been identified as a potentially revolutionary tool for psychological interventions. This study reviews current advances in immersive VR-based therapies for mental disorders. VR has the potential to make psychiatric treatments better and more cost-effective and to make them available to a larger group of patients. However, this may require a new generation of VR
PurposeThis paper aims to investigate the emergence of blockchain-enabled traceability in complex multi-tiered supply chains, focusing on the perspective of upstream suppliers. Blockchain technology receives attention for its potential to enable better traceability and thus sustainability risk management, yet there is limited empirical evidence on how actual implementation unfolds. We aim to under
This article considers students’ and teachers’ perceptions of shared reading (SR) in promoting reading engagement. It provides a thematic analysis of focus groups with students and teachers at a Swedish upper-secondary school who participated in an intervention consisting of SR sessions. The findings are triangulated with a student pre-intervention questionnaire that included reading habits.The st
DNA-encoded chemical libraries are increasingly used in pharmaceutical research because they enable the rapid discovery of synthetic protein ligands. Here we explored whether target-class focused DNA-encoded chemical libraries can be cost-effective tools to achieve robust screening productivity for a series of proteins. The study revealed that a DNA-encoded library designed for NAD+-binding pocket
Male gametogenesis occurs directly after uptake of malaria parasites by the mosquito vector and leads to the release of eight nucleated flagellar gametes. Here, we report that one of the two parasite actin isoforms, named actin II, is essential for this process. Disruption of actin II in Plasmodium berghei resulted in viable asexual blood stages, but male gametogenesis was specifically inhibited.
Quantification of face-to-face interaction can provide highly relevant information in cognitive and psychological science research. Current commercial glint-dependent solutions suffer from several disadvantages and limitations when applied in face-to-face interaction, including data loss, parallax errors, the inconvenience and distracting effect of wearables, and/or the need for several cameras to
Background: Fentanyl is commonly administered for procedural pain management in preterm infants, but target concentrations have not yet been defined. Methods: To investigate pharmacokinetics (PK), -dynamics (PD), and -genetics (PG), 25 infants (gestational age 23.3–34.1 weeks) received a fentanyl dose before a skin-breaking procedure (0.5 µg/kg) or tracheal intubation (2 µg/kg). Four pain scales w
Aim: Assess the prognostic ability of a non-highly malignant and reactive EEG to predict good outcome after cardiac arrest (CA). Methods: Prospective observational multicentre substudy of the “Targeted Hypothermia versus Targeted Normothermia after Out-of-hospital Cardiac Arrest Trial”, also known as the TTM2-trial. Presence or absence of highly malignant EEG patterns and EEG reactivity to externa
The age-standardized prevalence of Parkinson's disease (PD) has increased substantially over the years and is expected to increase further. This emphasizes the need to identify modifiable risk factors of PD, which could form a logical entry point for the prevention of PD. The World Health Organization (WHO) has recommended reducing exposure to specific environmental factors that have been reported
This paper introduces a conceptual framework: the CPS triangle, which has evolved over four years of research on ‘older people meet robots’. It is a synthesis of domestication theory, modern social practice theory and empirical data. Case studies on the domestication of one current technology, the robotic vacuum cleaner, and two emergent technologies, the eHealth system and the service robot, prov
Background: Adverse childhood experiences (ACE) can have negative effects on cognitive, social and emotion regulation abilities, which can threaten the child’s school integration and capacity to learn. While steady relations to sensitive, understanding adults may moderate these negative outcomes, the difficulties of children with ACEs pose a major challenge for teachers, whose insufficient prepara
