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CELL REPLACEMENT THERAPY FOR PARKINSON’S DISEASE: The importance of neuronal subtype, cell source and connectivity for functional recovery

Popular Abstract in Swedish Patienter som drabbats av Parkinsons sjukdom (PD) saknar förmågan att medvetet kontrollera sina rörelser. Livslång medicinering krävs, vilket lindrar symptomen och leder till att rörelsemönstret förbättras, men med varierad effektivitet. Trots att de läkemedel (t ex L-DOPA) som finns tillgängliga idag har fantastisk effekt, minskar deras effektivitet i takt med att sjukParkinson’s disease (PD) is a neurodegenerative disorder characterised by motor deficits such as slowness in movement, difficulty in initiating movement and tremor at rest. The cause of these motor symptoms is the selective loss of mesencephalic dopaminergic (mesDA) neurons, located in the substantia nigra (SN). These neurons project axons to the striatum where they release dopamine, a neurotransm

I geoekonomins tid

It is increasingly evident that the centre of gravity of international relations is shifting in the direction of Asia. China’s economic and political rise is the single most important dimension of this development. This coincides with fading American hegemony, obvious during, but in essence not limited to, the Trump Presidency. These actor-level changes take place within a context of structural chIt is increasingly evident that the centre of gravity of international relations is shifting in the direction of Asia. China’s economic and political rise is the single most important dimension of this development. This coincides with fading American hegemony, obvious during, but in essence not limited to, the Trump Presidency. These actor-level changes take place within a context of structural ch

Polarization transfer solid-state NMR for studying soft matter: From surfactants to the stratum corneum

Popular Abstract in English The word “motion” usually brings to mind movement from point A to point B. In the world of chemistry, this kind of motion is typically referred to as translational motion. Its consequences are experienced by us every time we smell a scent in the air or watch a dye spread in water. The fragrance is nothing else than molecules that fly in the air. Colour is molecules swimThe work presented in this thesis is dedicated to theoretical development, experimental testing and application of polarization transfer solid-state nuclear magnetic resonance (PT ssNMR). PT ssNMR is an analytical tool which provides detailed information about molecular mobility in model or simple soft matter systems at the low water content regime, enabling the creation of phase diagrams. Soft ma

Who can an organization believe in social media? Exploring the process of believability assessment

Data driven decision-making is becoming more and more important for an organization to stay competitive. Data collected and analyzed from social media can teach an organization about its customers in a way that was not possible before. However, in social media there is circulating a lot of data with questionable believability, such as fake news, which risks influencing an organization’s decision-m

Stackars deltidsanställda - ofrivilligt deltidsanställda och deras rätt till arbetslöshetsförsäkringen

The labor market, and therefore employment conditions, has changed in recent decades. Today, flexibilisation has led to a large number of employees who work part-time or lack permanent employment. An involuntary part-time worker refers to an individual who is working part-time and states that they want to work more hours than what the employer offers. As long as the employer complies with the prov

From Treatment First to Housing First: Managing Competing Professional Logics

In Sweden social work with homeless people is dominated by “Treatment First” (or the staircase model). The Treatment First models weak results in combating homelessness has increased the interest for Housing First. In 2015 we started a participatory design-oriented research project in the City of Helsingborg in Sweden that aims to implement principles of Housing First in a social housing programme

Production, purification and characterization of antibacterial biomolecules from an alkaliphilic Bacillus

Popular Abstract in English As there is a demand for new antibacterial agents due to antimicrobial resistance, the ability of one kind of microorganisms to produce antimicrobial substances has been evaluated. Then, after determining the antibacterial-producer microorganism, the production of active compound in large scale, followed by optimization the conditions investigated. Next, the bioactive aForty alkaliphiles, which were isolated from samples collected in Eastern Africa, have been screened for production of antibacterial compounds. One of these isolates, Bacillus halodurans B20, was able to produce a prominent amount of antibacterial activity against a Gram-positive bacteria on agar plates [paper I] and selected for further study. Production of the active compound in submerged culti

På väg mot en förståelse av fenomenet inkongruent predikativ : Ett försök att beskriva och förklara fenomenet samt skildra dess forskningshistoria

This thesis examines so-called pancake sentences, an agreement anomaly found in Swedish, Danish and Norwegian. In these languages, predicative adjectives typically agree with their subjects in number and grammatical gender. However, with certain subjects the predicative takes a t-form, corresponding to singular neuter, regardless of the number and gender of the subject. Such sentences are commonlyThis thesis examines so-called pancake sentences, an agreement anomaly found in Swedish, Danish and Norwegian. In these languages, predicative adjectives typically agree with their subjects in number and grammatical gender. However, with certain subjects the predicative takes a t-form, corresponding to singular neuter, regardless of the number and gender of the subject. Such sentences are commonly

UAS som nationell resurs - En studie av UAS-teknik, dess användning i svenska myndigheter och möjligheter till samverkan

Drones have been used by the military since mid-1970 but the development of autonomous systems from the turn of the millennium and onward has opened the area of UAV to civil service and the public immensely. Today UAV technology saves lives in Search And Rescue operations, complements and supports full scale vehicles at the Police force and assists in surveys and documentation of ground and forest

Lipase-Mediated Syntheses of Trimethylolpropane-Based Biolubricant and Cyclic Carbonate

Popular Abstract in English Popular Summary Since the beginning of mankind, humans have managed to find ways to make use of the resources available at hand in order to survive and even to improve their livelihoods. The basic needs for food as well as other amenities were met from plant- and animal resources until the 19th century when industrial revolution changed the base of production to fossilAbstract Biocatalysis is considered as benign and efficient alternative to chemical catalysis for organic syntheses. Lipases are the most versatile biological catalysts implemented so far with great potential for production of different chemicals and materials in non-conventional reaction media. This thesis presents investigations on lipase catalyzed esterification and transesterification reaction

Brandteknisk Riskvärdering av Sjötelegrafen köpcentrum

Sjötelegrafen Köpcentrum is a shopping mall located in Nynäshamn, Sweden. To examine the evacuation conditions in case of fire at Sjötelegrafen, a fire safety evaluation has been conducted. The report presents two dimensioning fire scenarios that are seen as representative for the shopping mall, these are fire in ICA Maxi and fire in Jysk. These different main scenarios were analyzed and simulated

Indoor Air Pollution, Passive Ventilation Strategies and Thermal Comfort in Nepal

Indoor Air Pollution (IAP) resulting from indoor burning of solid biomass fuels in poorly ventilated kitchens is a severe health risk in parts of the world where energy poverty is prevalent. Passive ventilation, i.e. taking advantage of naturally induced airflow has been suggested as crucial in reducing IAP levels below safe limits. Residents in high altitude settlements are however exposed to extImagine a house situated on 2 600 meters above sea level in the Himalayan mountain range. It is in the middle of January and – 2 degrees Celsius inside. The only source of additional heat you have access to is lighting an open fire or firing in the cooking stove, both of which you fuel with some kind of solid biomass such as wood or agricultural waste. The fire is intensifying, you begin to feel t

Making stuff- the agency of doing in non-growth contexts

This project has developed from the site and building conditions in an area of central Boden, a town in the inland north of Sweden. In post-war times, the city grew thanks to the military and regional hospital resulting in the development of the site Prästholmen that was realized true to the modernistic ideal of the time. Since then, Boden together with its inland neighbours, have struggled agai

23 § MBL och den allmänna avtalsrättens betydelse vid dess tillämpning

This paper concerns Sec. 23 the Codetermination at Work Act, and the necessary conditions for when a collective agreement is considered to exist and the relevance of contract of law when it is applied. The idea is to point at areas within contract of law that becomes particularly important at the application. The paper begins with a chapter that, in short terms, describes the background within co

Doing business for a “higher loyalty”? : How Swedish transnational corporations neutralise allegations of crime

In recent years, two Swedish companies have been a focus of substantial media attention: TeliaSonera and Lundin Petroleum. The defensive strategies employed by these two businesses to deal with allegations of crime will be analysed on the basis of Stanley Cohen’s theoretical work on processes of denial and neutralisation techniques. This paper will focus on a particular form of denial, namely the In recent years, two Swedish companies have been a focus of substantial media attention: TeliaSonera and Lundin Petroleum. The defensive strategies employed by these two businesses to deal with allegations of crime will be analysed on the basis of Stanley Cohen’s theoretical work on processes of denial and neutralisation techniques. This paper will focus on a particular form of denial, namely the