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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

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Group exhibition.'The horizon is always receding' brings together a selection of works that reflect on the scope and the implications that the term contemporary may have. As the philosopher Giorgio Agamben suggests, contemporaneity can be understood as a term that surpasses temporal demarcations and transcends simultaneity and coexistence. In this sense, this exhibition serves as a symptomatic dis

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A collaborative action research initiative was conducted in collaboration with professionals in a set of clinical research and development networks in a local health care system in Sweden. This is an examination of the interaction between engaging in collaborative action research practice and the power of tradition in health care. From observations and interviews with the coordinators of

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Accessibility today has a contradictory character. One the one hand, people with disabilities are welcomed and included, with ambitious promises in policies and declarations. On the other hand, they are still excluded in everyday practices. This volume explores this contradiction in three areas: city and transport, knowledge and education, and law, institutions and history. Sweden is the primary c

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Older people have more functional limitations than younger people and they form a segment of the population that is more dependent on mobility devices than other age groups. Since they spend most of their time at home, their dwelling is an important environmental arena for performing everyday activities. Barriers in the environment can limit or hinder activity performance. Therefore, older people

Infektionsmedicin

Flera forskningsprojekt vid vår avdelning är inriktade på att bättre förstå mekanismer som ligger bakom utvecklingen av svåra infektionssjukdomar, fr.a. orsakade av bakterier men också av virus och svampar. Utgångspunkten för arbetet har ofta varit upptäckten av bakteriella ytproteiner och enzymer som på olika sätt interagerar med människans försvarssystem (medfödd och förvärvad immunitet och blodSeveral research projects at our Division are focused on molecular and cellular mechanisms that contribute to the development of severe infections caused preferentially by bacteria, but also by viruses and fungi. The starting point for this work has often been the discovery of bacterial surface proteins and enzymes that interact with human defenses (innate and acquired immunity and blood coagulati

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On the basis of ethnographic fieldwork in Singapore, the article explores the tension between children's academic success and emotional wellbeing, and the ways in which middle-class parents navigate these conflicting aspirations. It delves into families with young children who pursue alternative lifestyles by moving abroad to a presumably less stressful environment or by homeschooling their childrOn the basis of ethnographic fieldwork in Singapore, the article explores the tension between children's academic success and emotional wellbeing, and the ways in which middle-class parents navigate these conflicting aspirations. It delves into families with young children who pursue alternative lifestyles by moving abroad to a presumably less stressful environment or by homeschooling their childr

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Multimedia has become one of the cornerstones of our 21st century society and, when combined with mobility, has enabled a tremendous evolution of our society. However, joining these two concepts introduces many technical challenges. These range from having sufficient performance for handling multimedia content to having the battery stamina for acceptable mobile usage. When taking a projection of w

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We present a method to add confidence limits to level curves, drawn on a map of a Gaussian random surface, measured with or without error on a regular or irregular grid. The method is based on the conditional level crossing intensity measure for non-stationary Gaussian fields.

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Damsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. This natural product is an inhibitor of NF- κB, a protein complex that controls the transcription of many genes in mammalian cells, and has a potential for standing model for the development of new anti-cancer lead structures. In order to improve the

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Inconel 718 is a Ni-based superalloy that can perform excellently at elevated temperatures. However, surface and subsurface damages in the form of microstructural and property changes and tensile residual stresses are common in a machined Inconel 718 component because of its poor machinability. Such damages have a significant influence on performance and the life time of the part. To characterise