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Background - In patients with chronic heart failure (CHF), a beta-blocker is generally added to a regimen containing an angiotensin-converting-enzyme ( ACE) inhibitor. It is unknown whether beta-blockade as initial therapy may be as useful. Methods and Results - We randomized 1010 patients with mild to moderate CHF and left ventricular ejection fraction <= 35%, who were not receiving ACE inhibitor
Background: Studies have shown that lifestyle interventions are effective in preventing or delaying the onset of type 2 diabetes in high-risk patients. However, research on the effectiveness of lifestyle interventions in high-risk immigrant populations with different cultural and socioeconomic backgrounds is scarce. The aim was to design a culturally adapted lifestyle intervention for an immigrant
The results of a search for electroweakino pair production pp→χ~1±χ~20 in which the chargino (χ~1±) decays into a W boson and the lightest neutralino (χ~10), while the heavier neutralino (χ~20) decays into the Standard Model 125 GeV Higgs boson and a second χ~10 are presented. The signal selection requires a pair of b-tagged jets consistent with those from a Higgs boson decay, and either an electr
Analyses with Point Scheme Risk Analysis method for hospital wards and event tree analysis at several ward at homes for the aged in order to evaluate the agreement between the two methods.
The Legal Principle of Equality underpins most national tax systems and encompasses both substantive and procedural equality. In its substantive form, the principle requires that equal treatment of equal situations. This does not mean however that unequal situations always merit unequal treatment. Political will may determine that particular distinguishing criteria should be discounted. Gender and
In the following case study, we have investigated how the fast fashion brand NA-KD uses discount codes as a marketing tool on Instagram with the help of influencers and what this in turn means for our consumption of fashion and clothing. In order to answer our research questions and gain a better understanding of this type of marketing, a qualitative content analysis was applied to two different v
This thesis seeks to examine the human rights due diligence (HRDD) requirements outlined in the EU proposal for the Corporate Sustainability Due Diligence Directive (CSDD proposal) for large EU limited liability companies (LLC), offering a comprehensive overview of these requirements. To further clarify and substantiate the HRDD provisions stated in the CSDD proposal, the thesis also includes a ca
Aims: Drug development for paediatric pulmonary arterial hypertension (PAH) ispressingly needed. Experts from the US Food and Drug Administration, EuropeanMedicines Agency, Health Canada, key opinion leaders, academia, patients, and industry representatives held a workshop on 12th June 2017 dedicated to addressing challenges and unmet needs. This report summarises the approaches proposed during th
Sommarkursen Arkeologi och förmedling Sommarkursen Arkeologi och projektledning. 13 juni – 15 juli Här kommer lite information om kursen i Arkeologi och förmedling Kursens fältdel förläggs under tre veckor till Uppåkra några kilometer söder om Lund. Det finns bussförbindelse till Uppåkra både från Lund och Malmö (buss 130) med stopp vid Uppåkra liksom en fin cykelväg från Lund. Det finns inte någo
Immunization is highly effective in preventing infectious diseases and therefore an indispensable public health measure. Allergic patients deserve access to the same publicly recommended immunizations as non-allergic patients unless risks associated with vaccination outweigh the gains. Whereas the number of reported possible allergic reactions to vaccines is high, confirmed vaccine-triggered aller
Patient specific QA procedures for IMRT from Lund University Hospital
Aim: The aim of this study was to evaluate the extent of white matter lesions, atrophy of the hippocampus and corpus callosum, and their correlation with cognitive dysfunction (CD), in patients diagnosed with systemic lupus erythematosus (SLE). Methods: Seventy SLE patients and 25 healthy individuals (HIs) were included in the study. To evaluate the different SLE and neuropsychiatric SLE (NPSLE) d
Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the bloodstream. Major depressive disorder has been associated with an increased amount of mtDNA in leukocytes from saliva samples and blood; however, no previous studies have measured plasma levels of free-circulating mtDNA in a
Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommenda
Introduction: Both decreased levels of brain-derived neurotrophic factor (BDNF) and hypothalamic–pituitary–adrenal (HPA) axis dysregulation may be involved in the pathophysiology of suicidal behaviour, as well as cognitive symptoms of depression. Pre-clinical and clinical studies have shown interactions between HPA-axis activity and BDNF, but this has not been studied in a clinical cohort of suici
The purpose of this study was to compare facial growth in patients with unilateral complete cleft lip and palate (UCLP) in whom the palate was repaired with the von Langenbeck procedure at 8 months (L-8), or the Wardill procedure at 18 months (W-18). A total of 151 unaffected subjects were used as a reference series. Sixty-one adult patients, 34 in the L-8 group and 27 in the W-18 group, were inve
Abstract in Danish Observationsmetoder og billeddannelsesteknikker ? vurderinger af den fysiske eksponering i repetitivt arbejde med focus på nakke, skuldre og arme Formålet var at udvikle, etablere og validere observationsmetoder til eksponeringsvurderinger i epidemiologiske undersøgelser af repetitivt arbejde. Et andet formål var at øge kvaliteten af input data til brug i biomekaniske skuldermoObservation methods and imaging techniques - assessments of physical exposure in repetitive work with focus on neck and upper extremities The aim of this thesis was to develop, establish and validate observation methods for exposure assessments in epidemiological studies of repetitive work. A second aim was to increase the quality of input data for biomechanical shoulder models, by reliability an
A search for flavour-changing neutral current (FCNC) tqH interactions involving a top quark, another up-type quark (q = u, c), and a Standard Model (SM) Higgs boson decaying into a τ-lepton pair (H → τ + τ −) is presented. The search is based on a dataset of pp collisions at s = 13 TeV that corresponds to an integrated luminosity of 139 fb −1 recorded with the ATLAS detector at the Large Hadron C
This paper presents a search for top-squark pair production in final states with a top quark, a charm quark and missing transverse momentum. The data were collected with the ATLAS detector during LHC Run 2 and correspond to an integrated luminosity of 139 fb−1 of proton-proton collisions at a centre-of-mass energy of s = 13 TeV. The analysis is motivated by an extended Minimal Supersymmetric Stand
