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Slututvärdering av det svenska landsbygdsprogrammet 2007–2013 : Delrapport II: Utvärdering av åtgärder för bättre miljö

SammanfattningRapporten är en del av slututvärderingen av Landsbygdsprogram för Sverige 2007-2013 och har tagits fram på uppdrag av Jordbruksverket. Den redovisar resultat och effekter som uppnåddes genom miljö- och klimatåtgärderna inom landsbygdsprogrammet, vilket omfattar samtliga insatser och ersättningar i axel 2, samt miljö- och klimatrelaterade utvärderingsfrågor för en del åtgärder i axel

Surgical age and morbidity after arterial switch of transposition of the great arteries

Background: Although transposition of the great arteries (TGA) accounts for less than 5% of congenital heart disease, the clinical course is often dramatic with need for early diagnosis and careful preoperative care as well as advanced surgical correction and postoperative support. Since 1993, Lund is one of the two tertiary referral centers for pediatric cardiac surgery in Sweden, with nearly 400

Root system estimation based on satellite remote sensing : An applied study in Eastern Uganda

The density of roots is an important factor influencing the rate and magnitude of landslides. Due to the increased variability in climate, mainly rainfall, Eastern Uganda is severely struck by an increasing number of these mass movements, often with human casualties as one of the negative impacts. The aim of this study is to explore the possibility to estimate the depth and density of the root sys

DNA Methylation of LRRC3B : A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients

Background: Previous studies support a tumor-suppressor role for LRRC3B across various types of cancers. We aimed to investigate the association between DNA methylation of LRRC3B and overall survival (OS) for patients with early-stage non-small cell lung cancer (NSCLC).Methods: This study included 1,230 patients with early-stage NSCLC. DNA was extracted from lung tumor tissues and DNA methylation

Transductive Image Segmentation : Self-training and Effect of Uncertainty Estimation

Semi-supervised learning (SSL) uses unlabeled data during training to learn better models. Previous studies on SSL for medical image segmentation focused mostly on improving model generalization to unseen data. In some applications, however, our primary interest is not generalization but to obtain optimal predictions on a specific unlabeled database that is fully available during model development

Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

PURPOSE: Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treatment. We evaluated the use of vemurafenib, a small-molecule BRAF inhibitor with immunomodulatory properties, as priming before TIL harvest and adopti

‘Someone must do it’ : multiple views on family’s role in end-of-life care – an international qualitative study

Background: Family is a crucial social institution in end-of-life care. Family caregivers are encouraged to take on more responsibility at different times during the illness, providing personal and medical care. Unpaid work can be overburdening, with women often spending more time in care work than men. Objectives: This study explored multiple views on the family’s role in end-of-life care from a

Alzheimer Disease Blood Biomarkers in Patients with Out-of-Hospital Cardiac Arrest

Importance: Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential alterations due to alternative mechanisms, such as hypoxia in patients resuscitated from cardiac arrest, are not known. Objective: To evaluate whether the levels and trajectories of blood p-tau, Aβ42, and Aβ40 following cardiac a

Serum neurofilament light levels are correlated to long-term neurocognitive outcome measures after cardiac arrest

Objective: To explore associations between four methods assessing long-term neurocognitive outcome after out-of-hospital cardiac arrest and early hypoxic-ischemic neuronal brain injury assessed by the biomarker serum neurofilament light (NFL), and to compare the agreement for the outcome methods. Methods: An explorative post-hoc study was conducted on survivor data from the international Target Te

Internet Use and Loneliness Among Older Adults : The Moderating Role of Self-perceptions of Ageing

Loneliness in advanced age has become one of the societal concerns considering its detrimental effects on physical and mental health of older people. Information and communication technologies show the potential to prevent or tackle loneliness and social isolation among older people. Given a percentage of the older population feeling lonely, loneliness in older age has been increasingly recognized

Prediction of Ki-67 expression of breast cancer with a multiparametric model using MRI parameters from ultrafast DCE-MRI and DWI

The purpose of this study is to investigate the prediction of Ki-67 expression of breast cancers using MRI parameters from ultrafast (UF) DCE-MRI, DWI, T2WI, and the lesion size. Breast MRI was performed with a 3T scanner using dedicated breast coils. UF DCE-MRI was obtained using Compressed Sensing-VIBE (prototype sequence). As a kinetic parameter of UF DCE-MRI, maximum slope (MS) was defined as

Direct or subacute coronary angiography in out-of-hospital cardiac arrest (DISCO)—An initial pilot-study of a randomized clinical trial

Background: The clinical importance of immediate coronary angiography, with potentially subsequent percutaneous coronary intervention (PCI), in out-of-hospital cardiac arrest (OHCA) patients without ST-elevation on the ECG is unclear. In this study, we assessed feasibility and safety aspects of performing immediate coronary angiography in a pre-specified pilot phase of the ‘DIrect or Subacute Coro

Centre for Statistical and Methodological Excellence (CESAME) : A Consortium Initiative for Improving Methodology in Randomised Clinical Trials

When conducting randomised clinical trials, the choice of methodology and statistical analyses will influence the results. If the planned methodology is not of optimal quality and predefined in detail, there is a risk of biased trial results and interpretation. Even though clinical trial methodology is already at a very high standard, there are many trials that deliver biased results due to the im

Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia

Traumatic brain injury (TBI) is a leading cause of chronic brain impairment and results in a robust, but poorly understood, neuroinflammatory response that contributes to the long-term pathology. We used single-nuclei RNA sequencing (snRNA-seq) to study transcriptomic changes in different cell populations in human brain tissue obtained acutely after severe, life-threatening TBI. This revealed a un

Sveriges utrikesfödda akademiker

Sveriges utrikesfödda akademiker Sveriges utrikesfödda akademiker Juni 2015 Josefin Edström Sveriges utrikesfödda akademiker Josefin Edström © Josefin Edström och Saco 2015 ISBN: 978-91-88019-07-3 www.saco.se 3 Förord Saco har under många år arbetat för att underlätta etableringen på arbetsmarknaden för utrikesfödda akademiker. Det är en grupp på arbetsmarknaden som inte är särskilt väldokumentera

https://www.saco.se/globalassets/bilder-video-och-dokument/sacos-rapporter/2015/2015_sveriges_utriksfodda_akademiker.pdf - 2026-04-21

Regional Brain Net Water Uptake in Computed Tomography after Cardiac Arrest – A Novel Biomarker for Neuroprognostication

Background: Selective water uptake by neurons and glial cells and subsequent brain tissue oedema are key pathophysiological processes of hypoxic-ischemic encephalopathy (HIE) after cardiac arrest (CA). Although brain computed tomography (CT) is widely used to assess the severity of HIE, changes of brain radiodensity over time have not been investigated. These could be used to quantify regional bra

Large regional variation in endovascular thrombectomy rates for acute ischemic stroke in Sweden

INTRODUCTION: Endovascular thrombectomy (EVT) is a significant improvement in the care of acute ischemic stroke (AIS) patients, but only a small portion of patients receive treatment. Our aim was to analyze EVT implementation in Sweden according to a set of key performance indicators (KPIs) for procedural and implementational effectiveness. METHODS: A nationwide prospective registry-based observ

Prolonged Fatigue and Mental Health Challenges in Critical COVID-19 Survivors

Background: The aim of this study was to investigate the development of fatigue and mental illness between 3 and 12 months after critical COVID-19 and explore risk factors for long-lasting symptoms. Study Design and Methods: A prospective, multicenter COVID-19 study in southern Sweden, including adult patients (≥18 years) with rtPCR-confirmed COVID-19 requiring intensive care. Survivors were invi

Efficient simulation of adaptive optics technologies for the Euro50 telescope

An efficient adaptive optics (AO) simulation code was developed, which enables first-order simulations of extremely high-order systems. The Monte-Carlo-type code employs a sparse conjugate gradient algorithm for wavefront reconstruction, and a separation of spatial frequencies into two domains to economize on the number crunching. High-order multi-conjugate adaptive optics (MCAO) systems are there