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A two-step Design of Experiments (DoE) strategy followed by a two-liquid-phase system (2LPS) was applied to enhance the ɛ-caprolactone yield in the cyclohexanone monooxygenase (CHMO)-alcohol dehydrogenase (ADH) convergent cascade system. The key reaction parameters were identified and optimized for the determination of an optimal operational window for the aqueous media. In the 2LPS system, high p
BACKGROUND: Guidelines recommend estimation of glomerular filtration rate (eGFR) prior to iodine contrast media (CM) examinations. It is also recommended that absolute eGFR in mL/min, not commonly used relative GFR (adjusted to body surface area; mL/min/1.73 m(2)), should be preferred when dosing and evaluating toxicity of renally excreted drugs.PURPOSE: To validate the absolute Lund-Malmö equatio
Environmental loads from the building and its services must be minimised. The study aims to determine material quantities, manufacturing energy and how material choice affect manufacturing energy. An inventory of materials in domestic water, waste water, space heating and ventilation services are made and manufacturing energy are calculated based on LCA’s. Finally energy need for alternative mater
Purpose: The aim of the study was to explore patients’ long-term experience of a congenital hand problem, and the consequences for daily life. Method: Fifteen participants with a median age 24 years (17–55 years), born with thumb hypoplasia/aplasia or thumb duplication were interviewed using a semi-structured interview guide. The interviews were subjected to qualitative content analysis. Results:
The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA - dis
The Historical Database of Scanian Agriculture (HDSA) is a micro-level database over farm production in the most southern Swedish region of Scania (Skåne) based on flexible tithes. It contains over 85,000 farm level observations of both vegetable and animal production for the period 1702 to 1881. Moreover, this information is supplemented by information on the farmer, the farm, on enclosures, natu
KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYT-LR), the representative sequence of helix D of heparin co-factor II, was demonstrated to be potent against agronomically important Gram-negative plant pathogens Xanthomonas vesicatoria and Xanthomonas oryzae, capable of inhibiting disease symptoms in detached tomato leaves. NMR studies in the presence of lipopolysaccharide provided structural insights into the mec
With older and aging populations, patients experience multiple chronic diseases at the same time. Individual chronic disease guidelines often recommend pharmacological therapies as a key intervention, resulting in patients being prescribed multiple regular medications for their different diseases. Although the term “polypharmacy” has been applied to the use of multiple medications, there is no con
In the Nordic countries, university language policy and planning centres on balancing the use of the national language(s) vis-à-vis English, whereas less attention has been paid to the roles played by other languages. This study focuses on how space was negotiated for languages other than Swedish and English during language policy negotiations at a Swedish university. Using an ethnographic discour
Chronic airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), together with their comorbidities, bear a significant burden on public health. Increased appreciation of molecular networks underlying inflammatory airway disease needs to be translated into new therapies for distinct phenotypes not controlled by current treatment regimens. On the other hand, development of ne
Chemogenetics is the process of genetically expressing a macromolecule receptor capable of modulating the activity of the cell in response to selective chemical ligand. This chapter will cover the chemogenetic technologies that are available to date, focusing on the commonly available engineered or otherwise modified ligand-gated ion channels and G-protein-coupled receptors in the context of neuro
We present measurements of elliptic and triangular azimuthal anisotropy of charged particles detected at forward rapidity 1
Mexico is the most transited corridor in the world. Beyond borderlands, human rights abuses committed against migrants pervade across transit communities and routes. In the interior of Mexico, not only at borders, the criminalization of migration has occurred having as a backdrop violence, xenophobia and insecurity in transit communities. Transit communities have developed complex relationships wi
A diversity of softwood lignin depolymerization processes yield guaiacol as the main low molecular weight product. This key aromatic compound can be utilized as a carbon source by several microbial species, most of which are Gram positive bacteria. Microbial degradation of guaiacol is known to proceed initially via demethylation to catechol, and this reaction is catalyzed by cytochrome P450 monoox
Historically, private initiative has always been of great significance for the arts. In most Europe-an countries the government took over from the private initiative after World War II. However, private initiative never completely disappeared, this is also true in the second half of the 20th century in which government subsidies were the dominant factor in the funding of the arts and cultural heri
