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Conversations about Death and Dying with Older People: An Ethnographic Study in Nursing Homes

Nursing homes are often places where older persons “come to die.” Despite this, death and dying are seldom articulated or talked about. The aim of this study was to explore assistant nurses’ experiences of conversations about death and dying with nursing home residents. This study is part of an implementation project through a knowledge-based educational intervention based on palliative care princ

Integration of Modelling Environments to an ÄKTA System

Automation: Optimering av din tid Tänk dig att du har fått en deadline på ditt nya projekt. Ditt arbete för projektet beror helt på din praktiska noggrannhet och tidsoptimering, samtidigt så ska du lämna in massvis med pappersarbete. Du har en tuff tid framför dig ifall du ska klara detta på egen hand inom tidsramen. Här kommer automatisering in i bilden. Det noggranna och tidskrävande arbetet soAutomated information flow is an important way of optimizing the time used for analyzing processes. Other added benefits are that in a well-made automated system, the probability of human error diminishes because less liability is put on the person to manually transport and utilize the data. This notion of automation can be applied to the field of chromatography. This thesis investigates the poss

Deduction of VAT on immovable property -Fiscal neutrality and Art 168a

The thesis starts with a description of the background to the change of the rules on deduction of VAT on mixed use immovable property through the insertion of Article 168a in the RVD. The reason according to the Amendment is to promote equity and to prevent unjustified cash-flow advantages granted to taxable persons who use acquire immovable property, deduct full input VAT and then pay it back o

Detecting longitudinal changes in activities of daily living (ADL) dependence : Optimizing ADL staircase response choices

Introduction: Using a sum score based on a three-graded response scale for the activities of daily living staircase has previously been found to increase the statistical power compared to dichotomized responses when assessing longitudinal changes in activities of daily living. We aimed to investigate if the statistical power could be further increased by using a four-graded scale. Methods: We used

Constructing radical right populist resistance : Metaphors of heterosexist masculinities and the family question in Sweden

The construction of radical right populist resistance around metaphors ofmasculinity at the beginning of the 21st century is a little researched area. Thisarticle accounts for the discursive redefinitions of Swedishness enabled byconceptual metaphors in order to accommodate centrally located heterosexistmasculinities at the intersection of gender, class, and ‘race’, as heralded by the main Swedish

Depression severity is associated with increased inflammation in veterans with peripheral artery disease

The present study examines the association between depressive symptoms and inflammatory markers in peripheral artery disease (PAD) to better understand the mechanistic relationship between depression and PAD. A cross-sectional sample of 117 patients with PAD (97% male, 76% Caucasian) was recruited from the San Francisco Veterans Affairs Medical Center. Patients were categorized into three subgroup

Synergistic effects of multiple “good agricultural practices” for promoting organic carbon in soils : A systematic review of long-term experiments

Loss of soil organic carbon (SOC) from farmland is a key threat to the capacity of soils to provide ecosystem services and exacerbates climate change. In alignment with a published protocol, we conducted a review and meta-analysis of time series of SOC measurements in long-term agricultural experiments to study absolute SOC changes under different agricultural management regimes. Our results show

Electrolyte disorders assessment in solid tumor patients treated with anti-EGFR monoclonal antibodies : a pooled analysis of 25 randomized clinical trials

The role of anti-epithelial growth factor receptor monoclonal antibodies (anti-EGFR MoAbs) in treatment-related electrolyte disorders is still controversial. Therefore, we conducted a meta-analysis of published randomized controlled trials (RCTs) to evaluate the incidences and overall risks of all-grade and grade 3/4 electrolyte disorder events. We searched relevant clinical trials from PubMed, EM

Scores of the Cleft Hearing, Appearance and Speech Questionnaire (CHASQ) in Swedish Participants With Cleft lip and/or Cleft Palate and a Control Population

Objective: The primary aim of this study was to investigate whether there was any difference in scores of the Cleft Hearing, Appearance and Speech Questionnaire (CHASQ) between patients with cleft lip and/or cleft palate (CL/P) and a control population. The second aim was to compare CL/P and control population scores in this study with a British norm CL/P population. Design: Single-site, cross-sec

Facilitating clinically relevant skin tumor diagnostics with spectroscopy-driven machine learning

In the dawning era of artificial intelligence (AI), health care stands to undergo a significant transformation with the increasing digitalization of patient data. Digital imaging, in particular, will serve as an important platform for AI to aid decision making and diagnostics. A growing number of studies demonstrate the potential of automatic pre-surgical skin tumor delineation, which could have t

Body mass index and weight gain in pregnancy and cardiovascular health in middle age : A cohort study

Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA). Design: Population-based cohort study. Setting: Swedish CardioPulmonary bioImage Study (SCAPIS). Population: A total of 8871 women from SCAPIS were include

Rational and evolutionary engineering of Saccharomyces cerevisiae for production of dicarboxylic acids from lignocellulosic biomass and exploring genetic mechanisms of the yeast tolerance to the biomass hydrolysate

Background: Lignosulfonates are significant wood chemicals with a $700 million market, produced by sulfite pulping of wood. During the pulping process, spent sulfite liquor (SSL) is generated, which in addition to lignosulfonates contains hemicellulose-derived sugars—in case of hardwoods primarily the pentose sugar xylose. The pentoses are currently underutilized. If they could be converted into v

Low-Dose Oral Ketamine for Procedural Analgesia in Pediatric Cancer Patients Undergoing Lumbar Puncture at a Resource-Limited Cancer Hospital in India

Aim: The aim of this study was to evaluate the therapeutic efficacy and safety profile of orally administered low-dose ketamine for procedural pain management in pediatric cancer patients undergoing lumbar puncture (LP) in a resource-limited hospital setting. Methods: Patients between 4 and 15 years of age, with leukemia, undergoing LP were asked to participate. The study was designed as a two-a

Relationship between somatostatin receptor expressing tumour volume and health-related quality of life in patients with metastatic GEP-NET

For patients with gastroenteropancreatic neuroendocrine tumours (GEP-NET), health-related quality of life (HRQoL) is important. Meanwhile, whether tumour volume is associated with HRQoL is unknown. Hence, the aim of this study was to assess if total somatostatin receptor expressing tumour volume is correlated with HRQoL in patients with metastatic GEP-NET. Some 71 patients were included in the stu

Level of sedation in critically ill adult patients : a protocol for a systematic review with meta-analysis and trial sequential analysis

Introduction It is standard of care to provide sedation to critically ill patients to reduce anxiety, discomfort and promote tolerance of mechanical ventilation. Given that sedatives can have differing effects based on a variety of patient and pharmacological characteristics, treatment approaches are largely based on targeting the level of sedation. The benefits of differing levels of sedation mus

Interactions in the 2×2×2 factorial randomised clinical STEPCARE trial and the potential effects on conclusions : a protocol for a simulation study

Background: Randomised clinical trials with a factorial design may assess the effects of multiple interventions in the same population. Factorial trials are carried out under the assumption that the trial interventions have no interactions on outcomes. Here, we present a protocol for a simulation study investigating the consequences of different levels of interactions between the trial interventio