Filtyp
The coefficient of friction (COF) and wear are critical parameters in assessing disc brake performance. However, their study is challenging due to their interdependence on contact pressure, sliding velocity, temperature, and material composition. The complex contact interactions between brake pads and discs involve the continuous formation and destruction of mesoscopic contact plateaus, which
Software is at the core of digitalisation and is often claimed to play a central role in innovation and in shaping competition across industries and firms. There are yet few studies of the extent and nature of software development across firms. We employ a unique firm-level survey comprising 3,929 firms across Sweden to analyse the distribution and characteristics of firms that invest in software
In the present work, we describe the design, synthesis, and evaluation of a galectin-8- binding fluorescent probe designed for a competitive fluorescence polarization (FP) assay for screening new galectin-8N inhibitors. The probe was characterized for its photophysical properties and its binding affinity for galectin-8N was determined by using FP. We evaluated the probe in a competitive FP assay w
Polycrystalline cubic boron nitride (PcBN) is renowned for its exceptional hardness and thermal stability, making it ideal for extreme machining conditions. Coatings on PcBN tools further enhance performance by extending tool life and improving cutting efficiency. While uncoated PcBN tools already excel in harsh environments, coatings primarily boost durability. Although extensively studied in tur
This systematic literature review assesses the current state of knowledge on how increased ICT use affects individual time-use patterns and the associated implications for lifestyle climate implications. While the environmental impacts of ICT have been widely debated in terms of direct energy consumption, there has been limited focus on the indirect time-use effects. The review draws on 101 articl
Accurate assessments of symptoms and illnesses are essential for health research and clinical practice but face many challenges. The absence of a single error-free measure is currently addressed by assessment methods involving experts reviewing several sources of information to achieve a best-estimate assessment. This assessment method is called the Expert Panel method in medicine, and the Best-Es
In recent years, researchers have extensively investigated hepatocellular carcinoma (HCC), a prevalent cancer type worldwide. Its resistance to conventional treatments highlights the promise of theragnostic nanoparticles, offering multiple tools within a single platform for fighting HCC cells. In this research, using polyaniline (PANI)-coated cobalt ferrite nanoparticles (CFO), an innovative nanoc
Background: Congenital heart disease (CHD) is the most common organ anomaly in humans affecting approximately 1:125 newborns worldwide. Early diagnosis enables postnatal stabilisation and may improve outcomes, especially in critical CHD, in which the circulation is dependent on patency of the arterial duct. Detection of CHD in newborns remains incomplete and current screening programs do not aim t
School-related functional impairment is common in children and adolescents with obsessive-compulsive disorder (OCD). However, little is known about the characteristics of youth with OCD who struggle in school, whether these struggles interfere with treatment outcomes, and whether treatment improves school-related function. Among 385 youth with OCD at a specialist clinic (mean age [sd] = 13.7 [2.5]
Recent studies have demonstrated that the transcription factor hepatocyte nuclear factor 4α (HNF4A) drives epithelial differentiation in the renal proximal tubules (PTs) and is critical for maintaining a mature PT phenotype. Furthermore, HNF4A down-regulation has been observed following kidney injury in mouse models. The aim of the present work was to investigate the role of HNF4A during acute and
Problem definition: Supply chain segmentation is a topic which in later years has received increasing attention from supply chain managers of companies in industrial settings. To members of the supply chain research community the ideas and theoretical contributions underlying the concept of supply chain segmentation are hardly new, but have evolved ever since the beginning of the 1990s. However, a
The so-called capitalist crisis of care has been theorized starting since the 80s. It has been and explored by two literature streams: the ‘feminist’ and the ‘mainstream’. New social and economic challenges in relation to welfare state systems trigger the interest of scholars and policy makers who are looking for sustainable responses to care needs. Welfare states have been repeatedly grouped into
Insects have been recommended by the FAO as a sustainable food alternative to meat. Despite their nutritional quality and sustainability, most Western countries still see insects as belonging far away from the dinner table. Although still a niche market, Denmark has been at the forefront of innovation and adoption of edible insects. I used integral theory to map out the structural, cultural and pe
Here a lung-on-a-chip device was developed and fabricated using 3D-printing of molds. The lung-on-a-chip device was used as a lung injury model by overstretching of murine lung epithelial cells (MLE-12) monolayers, resembling the injury during mechanical ventilation. The cells were exposed to 25% strain, representing pathological conditions seen in ventilator induced lung injury of patients with
Pupils tend to experience ‘attentional fatigue’ after persistently demanding their attentional system during school hours, resulting in decreased psychological well-being and a lack of attention, along with losses of other cognitive functions. Previous research found natural elements in a school environment to restore pupils’ depleted attentional system. The present study aimed at investigating na
How does anti-tourism affect support for the EU? This question has gained a newly found relevance in recent years, as anti-tourism protests have appeared in many European cities with high levels of tourism. Despite this relevance, some elements of these protests have not received as much attention as they deserve. This thesis will aim to fill one of the gaps in the literature: how anti-tourism soc
The rise of China and 1978-market reforms contrasts other post-socialist economies process of institutional and economic change. President Deng Xiaoping announced China’s continued commitment to socialism, yet his leadership is by some viewed to be the most radical social and economic transformation in contemporary Chinese history. One of the most extraordinary aspects of the Chinese reform period
Parental leave policies for fathers are introduced to promote father’s caregiving and gender equality in childcare. Even though the majority of father-friendly policy reforms were led by social democratic parties, a few conservative catch-all parties also proposed policies to promote father’s caregiving. How did conservative catch-all parties frame father’s caregiving when they propose policy refo
