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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Genome wide association studies (GWAS) have mapped multiple independent cancer susceptibility loci to chr5p15.33. Here, we show that fine-mapping of pancreatic and testicular cancer GWAS within one of these loci (Region 2 in CLPTM1L) focuses the signal to nine highly correlated SNPs. Of these, rs36115365-C associated with increased pancreatic and testicular but decreased lung cancer and melanoma r

Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia

Frontotemporal dementia (FTD) is the second most prevalent type of early-onset dementia and up to 40% of cases are familial forms. One of the genes mutated in patients is CHMP2B, which encodes a protein found in a complex important for maturation of late endosomes, an essential process for recycling membrane proteins through the endolysosomal system. Here, we have generated a CHMP2B-mutated human

eHealth usage among parents to premature or surgically treated neonates: associations with eHealth literacy, healthcare satisfaction or satisfaction with an eHealth device

BackgroundA specific eHealth device, a surf tablet, was developed for bridging between advanced in-hospital care and children’s homes. Since little is known about determinators for parental eHealth usage, the study’s aim was to explore if parents’ usage of the device was associated with their eHealth literacy, or their satisfaction with their child’s healthcare or with the specific surf tablet.Met

Maternal serum vitamin D level in early pregnancy and risk for preeclampsia : A casecontrol study in Southern Sweden

Background Preeclampsia is considered a major cause of maternal and fetal morbidity and mortality. The aim of the present case-control study in Sweden was to assess the hypothesized association between low serum vitamin D concentrations in early pregnancy and the risk of developing preeclampsia since vitamin D may play a role in early placental development. Methods The study included 296 women dia

In Vivo Photopolymerization : Achieving Detailed Conducting Patterns for Bioelectronics

Bioelectronics holds great potential as therapeutics, but introducing conductive structures within the body poses great challenges. While implanted rigid and substrate-bound electrodes often result in inflammation and scarring in vivo, they outperform the in situ-formed, more biocompatible electrodes by providing superior control over electrode geometry. For example, one of the most researched met

Particle formation during peristaltic pumping of therapeutic proteins : Hofmeister anions effect

This study reveals specific ion effects on particle formation during peristaltic pumping of a monoclonal Antibody (Antibody A). For this purpose, three anions in the direct Hofmeister series were selected, ranging from the kosmotropic SO42- to the more neutral Cl- and the chaotropic SCN-. Protein particle formation during peristaltic pumping is described primarily as a surface-driven mechanism. Th

Long-range transport influence on wintertime submicron aerosol chemical composition from simultaneous measurements in Lithuania and Southern Sweden

Due to the large extent of seawater surface over the globe, aerosol particles spend significant time being transported over this type of surface. Therefore, global aerosol circulation is largely impacted by the processes particles undergo during long-range transport overseas. In this study, we investigated submicron aerosol (PM1) chemical composition changes during long-range transport events over

Keystone protist suppression triggers mesopredator release and biotic homogenization in complex soil microbial communities

The keystone species concept holds that certain members of an ecological community, despite their low abundance, exert disproportionately large effects on species diversity and composition. In microbial ecology, experimental validation of this concept has been limited because targeted removal of individual species remains technically challenging. Here, we developed a procedure to test the keystone

Development and characterization of the Portable Ice Nucleation Chamber 2 (PINCii)

The Portable Ice Nucleation Chamber 2 (PINCii) is a newly developed continuous flow diffusion chamber (CFDC) for measuring ice nucleating particles (INPs). PINCii is a vertically oriented parallel-plate CFDC that has been engineered to improve upon the limitations of previous generations of CFDCs. This work presents a detailed description of the PINCii instrument and the upgrades that make it uniq

Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response

In the adult murine brain, neural stem cells (NSCs) can be found in two main niches: the dentate gyrus (DG) and the subventricular zone (SVZ). In the DG, NSCs produce intermediate progenitors (IPs) that differentiate into excitatory neurons, while progenitors in the SVZ migrate to the olfactory bulb (OB), where they mainly differentiate into inhibitory interneurons. Neurogenesis, the process of ge

Characterization of exposure to air pollutants for workers in and around fires

Firefighters can be occupationally exposed to a wide range of airborne pollutants during fire-extinguishing operations. The overall study aim was to characterize occupational exposure to smoke for several groups of workers responding to fires, with specific aims to determine the correlations between exposure markers and to biologically assess their systemic exposure to polycyclic aromatic hydrocar

Prior electrocardiograms not useful for machine learning predictions of major adverse cardiac events in emergency department chest pain patients

At the emergency department (ED), it is important to quickly and accurately determine which patients are likely to have a major adverse cardiac event (MACE). Machine learning (ML) models can be used to aid physicians in detecting MACE, and improving the performance of such models is an active area of research. In this study, we sought to determine if ML models can be improved by including a prior

Hsu chia sui jessica thesis 2011

Resilience in Space: An experimental analysis of resilience in urban flood management in the Taipei Basin Hsu Chia Sui Email: chiasui.hsu.academic@gmail.com Thesis Supervisor: Kimberly Nicholas Email: kimberly.nicholas@lucsus.lu.se A thesis submitted in partial fulfillment of the requirements of the Lund University International Master’s Programme in Environmental Studies and Sustainability Scienc

https://www.lumes.lu.se/sites/lumes.lu.se/files/hsu_chia_sui_jessica_thesis_2011_.pdf - 2026-04-25

Allman-studieplan-klinisk-medicin-2015-01-01

Microsoft Word - Allm studieplan klin med 2015.doc                 Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Medicinska fakultetsstyrelsen Allmän studieplan för utbildning på forskarnivå i klinisk medicin     (Fastställd  av  Medicinska  fakultetsstyrelsen  2007-­‐05-­‐24)     Studieplanen  träder  ikraft  

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-klinisk-medicin-2015-01-01.pdf - 2026-04-25

140306 formas handbook 2014

Formas’ Handbook 2011 Formas’ Handbook 2014| 1 Formas Handbook 2014 Formas’ Handbook 2014| 2 Formas Handbook 2014 - for applicants and reviewers Formas’ Handbook 2014| 3 TABLE OF CONTENTS FORMAS’ HANDBOOK FOR APPLICANTS AND REVIEWERS ......................................... 5 1. NEWS ..................................................................................................................

https://www.lub.lu.se/en/sites/lub.lu.se.en/files/140306_formas_handbook_2014.pdf - 2026-04-25

Up master genus beslut 2016-10-20

Brevmall Postadress Box 117, 221 00 LUND Besöksadress Allhelgona kyrkogata 14 M Telefon dir 046-222 08 01 växel 046-222 00 00 Webbadress www.genus.lu.se Genus vetens kapl iga ins t i tu t ionen A. Utbildningsplan för Masterprogram i Genus, migration och social rättvisa (Master of Science Programme (120 credits) in Gender, Migration and Social Justice) 120 högskolepoäng Avancerad nivå Programkod: S

https://www.genus.lu.se/sites/genus.lu.se/files/up_master_genus_beslut_2016-10-20.pdf - 2026-04-25

Underlag CSK 260401 ROK Doktoranders Arbetsmiljö 2026

Dokumentation av arbetsmiljörisker som en del av det systematiska arbetsmiljöarbetet Documentation of work environment risks in the systematic work environment management Situation/omständighet som riskbedömningen avser Situation/circumstance to which the risk assessment refers Universitetsövergripande riskbedömning gällande doktoranders arbetsmiljö och hälsa I samband med dialog om risker gälland

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-04/Underlag%20CSK%20260401%20ROK%20doktoranders%20arbetsmilj%C3%B6_2026.pdf - 2026-04-25

Infogallerikhm2svenska

Konsthögskolans galleri, KHM2, Bergsgatan 29, 3 våning Kontakta Sophie eller respektive tekniker om utrustning du vill låna. Kontakta Kristian i god tid för att planera transporten till lokalen. Samtransport från Khm till Galleriet och lastning av föregående utställningar för tillbakatransport till Khm, på måndag f.m. För att få tillträde till byggnaden, hissen och gallerirummet måste du ha ett LU

https://www.khm.lu.se/sites/khm.lu.se/files/infogallerikhm2svenska.pdf - 2026-04-25