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Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multia
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Objective To compare PET imaging of tau pathology with CSF measurements (total tau [t-tau] and phosphorylated tau [p-tau]) in terms of diagnostic performance for Alzheimer disease (AD). Methods We compared t-tau and p-tau and 18 F-AV-1451 in 30 controls, 14 patients with prodromal AD, and 39 patients with Alzheimer dementia, recruited from the Swedish BioFINDER study. All patients with AD (prodrom
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The demand for water recovery in the industry is increasingly important partly due to water shortage and partly due to tightening of regulatory requirements. In this paper water recovery solutions for two challenging types of wastewater - oily and polyvinylchloride (PVC) wastewater - are presented. The first part of the presentation analyses the operation and performance of a membrane unit operate
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The use of cross-flow ultrafiltration for the recovery of coating ma-terial from aqueous streams started about 30 years with electro deposition paint in the automotive industry. This early success can be related to both environmental and economical advantages of using ultrafiltration. Ultrafiltration recovers and concentrate electro deposition paint on the retentate side and produces purified wa
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Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupl
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Purpose: A hybrid planar-SPECT/CT method for tumor dosimetry in 177Lu-DOTATATE therapy, applicable to datasets consisting of multiple conjugate-view images and one SPECT/CT, is developed and evaluated. Methods: The imaging protocol includes conjugate-view imaging at 1, 24, 96, and 168 h post infusion (p.i.) and a SPECT/CT acquisition 24 h p.i. The dosimetry method uses the planar images to estimat
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The concern of this paper is with the mediatisation of tourism cities through fast circulating narratives on digital platforms in an era characterised as post-truth involving the spread of fake news and disinformation. Hence far, there is scarce knowledge on how misleading information and false rumours concerning terrorism affect the image of tourism cities. In addition, extant research studies pr
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Computerised tomography and magnetic resonance tomography were performed in nine faecally incontinent patients more than eight years after rectoplasty for high imperforate anus. No statistically significant correlation was found between function, i. e. degree of faecal incontinence, and anatomical findings. Thus, in spite of a detailed demonstration of the post-operative anatomy, the information d
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Bacteria utilize complement regulators as a means of evading the host immune response. Here, we describe protocols for evaluating the role vitronectin acquisition at the bacterial cell surface plays in resistance to the host immune system. Flow cytometry experiments identified human plasma vitronectin as a ligand for the bacterial receptor outer membrane protein H of Haemophilus influenzae type f.
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Synthetic and natural polymeric esters find applications in transport and construction sectors, where fire safety is an important concern. One polymer that is widely used is poly (methyl methacrylate) (PMMA), which almost completely undergoes thermal decomposition into methyl methacrylate (its monomer) CH2=C(CH3) - C(= O) - O - CH3 (MMA) at ~250–300°C. In order to analyze the high-temperature gas-
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The properties of combined multiplier and penalty function methods are investigated using a second-order expansion and results known for the Riccati equation. It is shown that the lower bound of the values of the penalty constant necessary to obtain a minimum is given by a certain Riccati equation. The convergence rate of a common updating rule for the multipliers is shown to be linear.
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Background: It is important to quantify a static posture to evaluate the need for and effectiveness of interventions such as physical management, physiotherapy, spinal orthosis or surgical treatment on the alignment of body segments. Motion analysis systems can be used for this purpose, but they are expensive, require a high degree of technical experience and are not easily accessible. A simpler m
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Novel carboxymethyl cellulose-chitosan (CMC-Cht) hybrid micro- and macroparticles were successfully prepared in aqueous media either by drop-wise addition or via nozzle-spray methods. The systems were either physically or chemically crosslinked using genipin as the reticulation agent. The macroparticles (ca. 2 mm) formed are found to be essentially of the core-shell type, while the microparticles
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The non line-of-sight (NLOS) scenario in urban intersections is critical in terms of traffic safety—a scenario where Vehicle-to-Vehicle (V2V) communication really can make a difference by enabling communication and detection of vehicles around building corners. A few NLOS V2V channel models exist in the literature but they all have some form of limitation, and therefore further research is need. I
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We study the problem of decomposing a measured signal as a sum of decaying exponentials. There is a direct connection to sums of these types and positive semi-definite (PSD) Hankel matrices, where the rank of these matrices equals the number of exponentials. We propose to solve the identification problem by forming an optimization problem with a misfit function combined with a rank penalty functio
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Background: Indications for negative-pressure wound therapy (NPWT) in vascular surgical patients are expanding. The aim of this review was to outline the evidence for NPWT on open and closed wounds. Methods: A PubMed, EMBASE and Cochrane Library search from 2007 to June 2016 was performed combining the medical subject headings terms 'wound infection', 'abdominal aortic aneurysm (AAA)', 'fasciotomy
