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BackgroundThe risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life stress (ELS) exposure during critical periods of brain development can impact later brain function and health, including increasing the risk of developing AD. Microglial dysfunction and neuroinflammation have been implicated as playing a role in AD pathology and may be modulated

Laser diagnostic techniques have for more than five decades been used for gaining a deepened understanding of various combustion processes. The main reason for this is the possibility of non-intrusive measurements of key combustion parameters, e.g. species concentrations, temperatures and velocities, with high spatial and temporal resolution. The present paper will describe some development of the

We present the use of a high capacity and high throughput acoustic trapping platform for phenotypic characterization and functional studies of extracellular vesicles (EVs) from pathogen activated platelets. Platelet rich plasma was stimulated with bacterial M1 protein isolated from S. Pyogenes, which is known to activate platelets. The subsequently released platelet EVs were isolated from 400 μL p

This is a commentary on the European Court of Human Rights’ judgment in the CASE OF DELFI AS v. ESTONIA. This text represents the English first version that was translated and published in the Latvian weekly legal journal Jurista vards, in a special issue on the Delfi case.

Power systems are a vital infrastructure for the functioning of the society, generally regarded as one of the most critical infrastructures. Past power system blackouts (e.g., the Canadian ice-storm and New-Zeeland Power outage in 1998, the U.S. blackout in 2003, the European blackout in 2006 and the Indian blackout in 2012) have revealed the inherent vulnerabilities of power systems as well as th

Background and aims: Asthma is one of the most common respiratory diseases in the world. Research has shown that temporal increases in air pollution concentrations can aggravate asthma symptoms. The aim of this study was to assess whether individuals living in areas with higher air pollution concentrations responded differently to short-term temporal exposure to air pollution than those living in

This thesis proposes an autoregressive credit spread model to make long term simulations of credit spreads and credit indices in the Investment grade and High yield bond segments. Several models are tested, and the final spread model produces simulations with statistics consistent with historical data, even though the model itself is relatively parsimonious. A transition from spread to index is pro

Popular Abstract in Swedish Hjärt- och kärlsjukdomar är idag den vanligaste dödsorsaken i stora delar av världen för både män och kvinnor. I Sverige är hjärtinfarkt den vanligaste dödsorsaken för kvinnor över 55 år och för män över 45 år. Det vill säga kvinnor drabbas cirka 10 år senare. Tidigare forskning har baserats i huvudsak på män varvid forskning på kvinnor med hjärt- och kärlsjukdomar har Background: Coronary heart disease (CHD) is the sleading cause of mortality in men and women in Western society. Few studies of CHD have been performed on women or with a focus on cardiac risk factors in women’s lives. Results from studies of men have been generalized to women, which may be inappropriate or even dangerous. Aim: The overall aim of this thesis was to describe women’s experience of a

A dye-binding method using Acid Orange 12 was investigated regarding its suitability for the quantification of available lysine, as a means of monitoring the Maillard reaction in skim milk powders. The method was evaluated by analyzing a wide range of milk powders produced by three different drying methods and stored under various conditions. A pilot-scale freeze-dryer, spray-dryer and drum-dryer

In an organization where the safety level is high and incidents and serious accidents are very rare, a steady erosion of safety awareness and protective measures can occur, especially when productive demands rise. Thus, it is important to continuously identify and monitor aspects in the organization that can affect work performance and safety. In an ongoing joint research project between the LFV G

Popular Abstract in Swedish Jordens dotter. Selma Lagerlöf och den tyska hembygdslitteraturen. Avhandlingen undersöker mottagandet av Selma Lagerlöfs verk i Tyskland åren runt sekelskiftet 1900. Selma Lagerlöf introducerades på den tyska bokmarknaden 1896 med en översättning av debutverket Gösta Berlings saga. Redan tidigt under sin litterära karriär uppmärksammades hon i tysk press och nådde på This dissertation studies the reception of the works of the Swedish author Selma Lagerlöf in Germany at the turn of the century 1900. Selma Lagerlöf was introduced into the German book market in 1896, with a translation of her first novel, “The Saga of Gosta Berling”. She was well received by the German press and had after only a couple of years managed to get herself an impressive readership, whi

The purpose of this paper is to explore in what way the place becomes important for those who are affected by disasters or sudden death. According to human geography people have affective bonds to the concrete physical places where they are living and moving in their everyday live. Places are also constructed as meeting places where people create social relations. In the discotheque fire in Gothen

Background: Medical treatment of hypertension is not always sufficient to achieve blood pressure control. Despite this, previous studies on supplementary therapies, such as yoga, are relatively few. We investigated the effects of two yoga interventions on blood pressure and quality of life in patients in primary health care diagnosed with hypertension. Methods: Adult patients (age 20-80 years) wit

The integration of risk reduction and climate change adaptation has become an urgent task in addressing increasing urban risk more effectively and efficiently. This paper analyses the extent to which climate change adaptation is integrated into the policies and regulatory frameworks that guide urban risk reduction in Nicaragua, and discusses related progress. The results reveal significant progres

The effect of heat treatment on the soluble protein content in oat groats (Kerstin commercial variety) was evaluated using asymmetric flow field-flow fractionation (AF4) in combination with online multiangle light scattering (MALS) and UV detection. The AF4 method was used to separate the monomeric proteins from globulin hexamer and aggregate proteins and beta-glucan polysaccharides in the soluble