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Introduction: Human body acceleration is often used as an indicator of daily physical activity in epidemiological research. Raw acceleration signals contain three basic components: movement, gravity, and noise. Separation of these becomes increasingly difficult during rotational movements. We aimed to evaluate five different methods (metrics) of processing acceleration signals on their ability to

Journal of Parkinson’s Disease xx (2022) x–xx DOI 10.3233/JPD-223452 IOS Press 1 Review A Combined -Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System Anders Björklund∗, Fredrik Nilsson, Bengt Mattsson, Deirdre B. Hoban and Malin Parmar Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Wallenberg Neu

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/2022-10/publication%20in%20jpd-prepress.pdf - 2026-05-04

Tentamensfrågor.xlsx Instuderingsuppgifter EXTP45 Nr Fråga Poäng Avsnitt Föreläsare 1 Definiera kerma. 1 Dosimetri - teori CC 2 Definiera absorberad dos. 1 Dosimetri - teori CC 3 Definiera restricted cema. 1 Dosimetri - teori CC 4 Beskriv olika typer av strålningsjämvikt. 2 Dosimetri - teori CC 5 Beskriv hur små och stora kaviteter påverkar fluensen av laddade partiklar. 2 Dosimetri - teori CC 6 F

https://www.msf.lu.se/sites/msf.lu.se/files/instuderingsfragor.pdf - 2026-05-04

1 3 Acta Neuropathol (2014) 127:283–295 DOI 10.1007/s00401-013-1219-1 CAse RepORt The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast‑derived neurons Mariangela Iovino · Ulrich Pfisterer · Janice L. Holton · Tammaryn Lashley · Robert J. Swingler · Laura Calo · Rebecca Treacy · Tamas Revesz · Malin Parmar · Michel Goedert · Mira

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_acta_neuropathol.pdf - 2026-05-04

t/4 Dnr STYR 2018/717 LUNDS UNIVERSITET Rektor Vidarefördelning av uppgifter inom arbetsmiljö- och brandskyddsarbete från dekan' (motsv.) till prefekt (motsv.) och vidare, bilaga2 Undertecknad chef/befattning ftrdelar uppgifter enligtFöreslcrifter omfordelning av uppgifter inom arbetsmiljö och brandslqtdd vid Lunds universitet, STYR 2016/1045 fiir: Centrum ftir miljö- och klimatforskning, ICOS Swe

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/delegering_av_uppgifter_inom_arbetsmiljo-_och_brandskyddsarbete_till_anders_bath_190101.pdf - 2026-05-04

Microsoft Word - Neurology Clinic report 2019.docx Neurology clinic 1. Short description of the platform Well-trained and experienced research nurses, research coordinators and research doctors are the backbone of the clinical research activities and have over the years become an essential asset to conduct studies. Currently at the department of neurology there are more than 500 patients enrolled

https://www.multipark.lu.se/sites/multipark.lu.se/files/neurology_clinic_report_2019_.pdf - 2026-05-04

10 Questions: Clinical Outlook for iPSCs Cell Stem Cell Forum 10 Questions: Clinical Outlook for iPSCs Cell Stem Cell Editorial Team1,* 1Cell Stem Cell, Cell Press, 50 Hampshire Street, 5th Floor, Cambridge, MA 02139, USA *Correspondence: stemcell@cell.com http://dx.doi.org/10.1016/j.stem.2016.01.023 In an interview, we recently asked four leaders in the field to share their insights with us on th

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/10qs_ipsc.pdf - 2026-05-04

Background Treatment of relapsing-remitting multiple sclerosis with interferon beta is only partly effective, and new more effective and safe strategies are needed. Our aim was to assess the efficacy of oral methylprednisolone as an add-on therapy to subcutaneous interferon beta-1a to reduce the yearly relapse rate in patients with relapsing-remitting multiple sclerosis. Methods NORMIMS (NORdic tr

Direct electron transfer (DET) reactions of recombinant tobacco peroxidase (rTOP), namely direct electroreduction of Compound I/ Compound II and heme Fe3+/2+ conversion, were studied on gold electrodes. rTOP of wild type, non-glycosylated, was produced using, an Escherichia coli expression system. At pH 5.0, the redox potential for direct electrochemical transformation of the Fe3+/2+ of the peroxi

The apolipoprotein (apoE) epsilon4 allele was studied in fronto-temporal dementia (FTD), a diagnostic category including the specific disorders Pick's disease and frontal lobe degeneration of non-Alzheimer type (FLD). These dementing diseases have neuronal and synaptic degeneration in common with Alzheimer's disease (AD), for which the presence of the apoE epsilon4 allele is a known risk factor, a

Aims/hypothesis Post-translational modifications, such as isomerisation of native proteins, may create new antigenic epitopes and play a role in the development of the autoimmune response. Protein-L-isoaspartate (D-aspartate) O-methyltransferase (PIMT), encoded by the gene PCMT1, is an enzyme that recognises and repairs isomerised Asn and Asp residues in proteins. The aim of this study was to asse

Aims/hypothesis Most studies of diet in glucose intolerance and type 2 diabetes have focused on intakes of fat, carbohydrate, fibre, fruits and vegetables. Instead, we aimed to compare diets that were available during human evolution with more recently introduced ones. Methods Twenty-nine patients with ischaemic heart disease plus either glucose intolerance or type 2 diabetes were randomised to re

We conducted pooled and meta-analyses of the association of the calpain-10 gene (CAPN10) polymorphisms SNP-43, Indel-19 and SNP-63 individually and as haplotypes with type 2 diabetes (T2D) in 3237 patients and 2935 controls of European ancestry. In the pooled analyses, the common SNP-43*G allele was associated with modest but statistically significant increased risk of T2D (odds ratio (OR) = 1.11

Industrial biotechnology has been defined as the use and application of biotechnology for the sustainable processing and production of chemicals, materials and fuels. It makes use of biocatalysts such as microbial communities, whole-cell microorganisms or purified enzymes. Although biocatalysts are considered advantageous, since they operate under mild conditions regarding temperature and pH and e

BACKGROUND: While a dose-response relationship between physical activity and risk of diabetes has been demonstrated, few studies have assessed the relative importance of different measures of physical activity on diabetes risk. The aim was to examine the association between different self-reported measures of physical activity and risk of type 2 diabetes in a prospective cohort study. METHODS: Out

Introduction Osteoarthritis (OA) of the first carpometacarpal (CMC-1) joint is a common hand disorder with symptoms including pain and weakness of the thumb. Previous studies have associated high BMI with OA of weight-bearing joints, whereas studies regarding non-weight-bearing joints have shown conflicting results. Thus, the aim of this study was to investigate the influence of overweight and obe

Objectives: To investigate the prevalence of pathological disease and spectrum of human papillomavirus (HPV) types among symptomatic foreskin tissue. Patients and Methods: Consecutively excised symptomatic foreskins from 351 men were sent for histopathological evaluation. During the surgical procedure, a fresh biopsy was taken for HPV analysis by modified general primer polymerase chain reaction.

Purpose: Three-dimensional, time-resolved blood flow measurement (4D-flow) is a powerful research and clinical tool, but improved resolution and scan times are needed. Therefore, this study aims to (1) present a postprocessing framework for optimization-driven simulation-based flow imaging, called 4D-flow High-resolution Imaging with a priori Knowledge Incorporating the Navier-Stokes equations and

Objective Heart failure (HF) frequently complicates atrial fibrillation (AF) and significantly increases mortality risk. Limited data exist on the modifiable risk factors associated with development of HF in AF patients. Methods We examined two large, prospective, population-based cohorts without prior AF or HF at baseline: Malmö Preventive Project (MPP, n=32 625) and Malmö Diet and Cancer Study (