Filtyp
This thesis, which is based on four original papers, deals with human dendritic cells (DCs) in immunity and allergy. DCs play a key role in the regulation of immune responses by acting as the sentinels of the immune system, specialized in the uptake of a diverse range of antigens. These cells migrate to local lymph nodes and become highly efficient in inducing T cell proliferation, thus inducing a
This report was initiated and conducted as input to the discussions based on the “Vision 2015” document for the Nordic Swan that explicitly states a wish to find ways to make use of ecolabelling in the green public procurement (GPP) setting. In 2014, the Directive (2004/18/EG) on public procurement was revised and replaced by Directive (2014/24/EU). Some of the restrictions in using ecolabelling i
We investigate a model for buffer management of multi-class traffic into a finite shared buffer. A hierarchy of increasingly stronger linear programming relaxations for this model is proposed. The number of hierarchies equals the number of job classes. Each relaxation in the hierarchy is constructed by projecting the original achievable performance region into a polytope with fewer variables and f
Abstract in UndeterminedIn today's technology generations, e.g. 90 and 65 nm, the static power consumption becomes a major contributor to the total power consumption. This paper focuses on the arithmetic level and shows a methodology for a substantial reduction of the static power consumption. Simulations are done in a typical 130 nm technology. Based on the simulation results, the static power in
Sweden is part of a small European minority in the perceived societal gain of PPP. After a pilot PPP project in late 1990’s no additional project has been started in Sweden. Although there is interest from both public infrastructure clients and construction companies the national government has very clearly stated that infrastructure projects should be procured in a traditional way where all fundi
The ATLAS Collaboration at CERN is preparing for the data taking and analysis at the LHC that will start in 2007. Therefore, a series of Data Challenges was started in 2002 whose goals are the validation of the Computing Model, of the complete software suite, of the data model, and to ensure the correctness of the technical choices to be made for the final offline computing environment. A major fe
How do small states approach their security problems? What types of strategic instruments exist for small states, and when and why are certain strategies chosen rather than others? The security of `weak' states is problematic, demanding trade-offs in the decisions made. Using 19th century Swedish security policy as an example, it is argued here that small states, in their pursuit of security and a
The lactic acid bacterium, Streptococcus thermophilus, is used in the dairy industry in mixed cultures with Lactobacillus delbrueckii subsp. bulgaricus for the production of yoghurt. Many strains of S. thermophilus produce exopolysaccharides (EPSs) which affect the texture and viscosity of fermented food products. However, the production of EPSs by S. thermophilus is low and variable, and better k
Abstract in UndeterminedSubject-specific finite element models have been used to predict stress-state and fracture risk in individual patients. While many studies analysed quasi-axial loading configurations, only few works simulated sideways load configurations, such as those arising in a fall. The majority among these latter directly predicted bone strength, without assessing elastic strain predi
Apolipoprotein M (ApoM) is a 25-kDa HDL-associated apolipoprotein and a member of the lipocalin family of proteins. Mature apoM retains its signal peptide, which serves as a lipid anchor attaching apoM to the lipoproteins, thereby keeping it in the circulation. Studies in mice have suggested apoM to be antiatherogenic, but its physiological function is yet unknown. We have now determined the 1.95
Lipid membrane and lipopolysaccharide (LPS) interactions were investigated for a series of amphiphilic and cationic peptides derived from human heparin cofactor II (HCII), using dual polarization interferometry, ellipsometry, circular dichroism (CD), cryoTEM, and z-potential measurements. Antimicrobial effects of these peptides were compared to their ability to disorder bacterial lipid membranes,
The immobilization of functional biomolecules to surfaces is a critical process for the development of biosensors for disease diagnostics. In this work we report the patterned attachment of single chain fragment variable (scFv) antibodies to the surface of metal oxides by the photodeprotection of self-assembled monolayers, using near-UV light. The photodeprotection step alters the functionality at
Chiral bicyclic diols based on bicyclo[2.2.2]octane and bicyclo[2.2.1]heptane have been synthesized and their catalytic capacity in the asymmetric diethylzinc addition to benzaldehyde compared with those described for previously synthesized 2,6-bicyclo[2.2.2]octane-diols (BODOLs). The influence of the number of coordinating sites and the distance between them were studied. (C) 2008 Elsevier Ltd. A
