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Microfluidic techniques were applied to the separation of parasite and parasite-infected cells from blood to facilitate the detection of leishmaniasis, a disease representing a high burden in the developing world and for which new diagnostic tools are urgently needed. Leishmania mexicana promastigotes were successfully separated from red blood cells in a deterministic lateral displacement device.
Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associa
This study describes the design of degenerate primers and their use for synthesis of full-length avian influenza A neuramindase (NA). Each reaction was performed using either two forward primers and one reverse primer, or one forward primer and one reverse primer. Both primer combinations had comparable amplification efficiencies for all NA subtypes (1-9). A total of 115 virus strains, including b
Baker’s yeast, Saccharomyces cerevisiae, is a promising cell factory for the sustainable utilization of renewable resources for the formation of products with commercial value. Among these, poly-3-D-hydroxybutyrate (PHB) is an extensively studied biopolymer naturally accumulated in some bacteria and archaea species through the formation of carbon granules. Its bio-based origin, biodegradability an
Background: Funding models influence provision and development of palliative care services. As palliative care integrates into mainstream health care provision, opportunities to develop funding mechanisms arise. However, little has been reported on what funding models exist or how we can learn from them. Aim: To assess national models and methods for financing and reimbursing palliative care. Desi
The international legal framework regulating the problem of human trafficking contains the presumption that the return of victims of human trafficking to their countries of origin is the standard resolution for their cases. However, victims might have legitimate reasons for not wanting to go back. For those victims, resort to the legal framework of the European Convention on Human Rights could be
This article aims at introducing to a wider circle a complementary research approach in user oriented work. Its most fundamental part is the use of technology as a tool for capturing the needs, wishes and dreams of a user. The incitement for us to start developing this method was an experience based, serious, questioning of conventional methods such as interviews, questionnaires, etc, and their c
The quasi-linear Maxwell equations describing electromagnetic wave propagation in nonlinear media permit several weak solutions, which may be discontinuous (shock waves). It is often conjectured that the solutions are unique if they satisfy an additional entropy condition. The entropy condition states that the energy contained in the electromagnetic fields is irreversibly dissipated to other energy
This paper describes the development of St Anne's festival, celebrated by the Mi'kmaq each year for centuries. It is a case study of a "space" where Indian traditions and Christianity btought by Catholic missionaries meet, clash and merge.
