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In order to investigate the possible causes of premature thermal breakdown and performance degradation, several diagnostic techniques have been employed during the vertical tests of the Fine and Large Grain ESS Medium Beta prototypes cavities. The whole equipment, which includes second sound, fast thermometry, photodiode x ray detectors and external NaI scintillator and proportional counter, is he
Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it is not fully understood how and when the onset of circulation affects HSC emergence. Here we show that in Ncx1−/− mouse embryos devoid of circulation the HSC l
The purpose of this perspective article is to critically explore the launch of the mission for 100 climate neutral cities in Europe. An overview of the mission approach in general is first presented, where key aspects and emerging critiques are identified. Second, key elements of the mission for 100 climate neutral cities in Europe are introduced along with some of its challenges and ambiguities.
Accuracy in MP2RAGE-based T1-mapping relies on knowledge of the imperfect inversion efficiency (finv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86, which is substantially lower than the finv=0.96 typically assumed in MP2RAGE. We further observed a lower finv in white matter (WM) than in the
The capacitive biosensor technology can be utilized for the analytical detection of a variety of different compounds. By employing the electrical double-layer principle, it is possible to detect very low concentrations of the target analyte due the methods inherent high sensitivity. This affinity-based capacitive biosensor is a powerful tool also for the analytical detection of low molecular weigh
In recent years there has been a great deal of discussion on the potential for a shift away from modernistic or technocratic approaches to decisionmaking on risk towards more open, inclusive, and deliberative approaches. The authors consider (a) the reasons why some companies have taken the first step in this transition by exploring the potential of more open and communicative approaches to enviro
Background: To reduce local recurrence risk, rectal washout (RW) is integrated in the total mesorectal excision (TME) technique when performing anterior resection (AR) for rectal cancer. Although RW is considered a safe practice, data on the complication risk are scarce. Our aim was to examine the association between RW and 30-day postoperative complications after AR for rectal cancer. Methods: Pa
Existing criteria for inclusion in the European baseline series are summarized. Additional criteria are developed to aid decision making where the current criteria do not yield an unequivocal result. These include a consideration of whether an allergen (hapten) is better placed in a special series and the frequency with which an allergen cross-reacts with existing markers in the baseline series.
The European steel industry must achieve deep greenhouse gas emission reductions to become climate neutral by 2050. New business models are often proposed as one of the key solutions but are mostly addressed in general terms, without elaborating on or systematically analyzing how these new business models are actually linked to specific mitigation measures or strategies. In this paper, we assess w
The study of a turbulent premixed flame often involves analysing quantities conditioned to different iso-surfaces of a reactive scalar field. Under the influence of turbulence, such a surface is deformed and translated. To track the surface motion, the displacement speed of the scalar field respective to the local flow velocity is widely used and this quantity is currently receiving growing attent
(KxNa1-x)NbO3 (KNN) and its solid solutions are considered as potential alternatives to traditional Pb-based piezoelectric materials. Recent investigations indicated that the local structure in KNN is much more complex than its long-range average structure. Here, we have undertaken a systematic investigation of the temperature-dependent evolution of local and average structures of KNN5 [(KxNa1-x)N
The various problems associated with co-authorship of research articles have attracted much attention in recent years. We believe that this (hopefully) growing awareness is a very welcome development. However, we will argue that the particular and increasing importance of authorship and the harmful implications of current practices of research authorship for junior researchers have not been emphas
Whether and how long-term energy and climate targets can be reached depend on a range of interlinked factors: technology, economy, environment, policy, and society at large. Integrated assessment models of climate change or energy-system models have limited representations of societal transformations, such as behavior of various actors, transformation dynamics in time, and heterogeneity across and
The European Commission describes a Circular Economy (CE) as an economy “where the value of products,materials and resources is maintained in the economy for as long as possible, and the generation of waste minimised.”But what is value in this context and how should CE policies consider value? Extended producer responsibility(EPR) policies are an important part of an EU CE Action Plan. However, th
Ambient temperature strongly determines the behaviour, physiology, and life history of all organisms. The technical assessment of organismal thermal niches in form of now so-called thermal performance curves (TPC) thus has a long tradition in biological research. Nevertheless, several traits do not display the idealized, intuitive dome-shaped TPC, and in practice assessments often do not cover the
