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The possibility to make environmental strategy a part of the core strategy through a framework called inside-out/outside-in was suggested by Porter in 2007. Researchers have also stated that the output of implementing a certain strategy ought to be valued during strategy planning. The two areas; environmental strategy and profitability analysis have although not frequently been combined, and thus
Most drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca
The report presents the results of a review of the study methods related to vulnerable road user safety that are used today and aims to link accident causation factors to VRU accident risk. The review covered the following categories of study methods: epidemiological studies based on accident and injury data; in-depth accident investigations; naturalistic driving studies; behavioural observations;The report presents the results of a review of the study methods related to vulnerable road user safety that are used today and aims to link accident causation factors to VRU accident risk. The review covered the following categories of study methods: epidemiological studies based on accident and injury data; in-depth accident investigations; naturalistic driving studies; behavioural observations;
Discover how the master’s programme in Photonics combines strong academic foundations, supportive teaching and hands-on learning, through the experience of Marzo who graduated from the programme in 2025.Discover how the master’s programme in Photonics fosters independent thinking, collaboration and hands-on learning in an international study environment, through the experience of Marzo who graduated from the programme in 2025.
The goal of this study is to investigate the applicability of asymmetrical flow field-flow fractionation (AsFlFFF)–multi angle laser light scattering (MALLS), and to develop a method for analysis of cationic potato amylopectin (CPAP) having ultrahigh molecular mass (UHMr). Use of the aqueous carrier having low salt content (3 mM NaN3) resulted in a distortion in AsFlFFF fractograms of CPAP with a
The random k-SAT model is one of the most important and well-studied distributions over k-SAT instances. It is closely connected to statistical physics and is a benchmark for satisfiability algorithms. We show that when k=Θ(log n) , any Cutting Planes refutation for random k-SAT requires exponential length in the regime where the number of clauses guarantees that the formula is unsatisfiable with
Background: There are no data showing that disperse dyes, used to patch test patients, are currently being used for dyeing synthetic garments. It is unknown whether disperse dyes, which are currently routinely patch tested, are in fact present in synthetic textiles on the market. Objectives: To determine whether eight disperse dyes, hitherto most widely cited as allergenic, are still used in tex
In this paper, I evaluate the usefulness of protein homology models in rigorous free-energy simulations to determine ligand affinities. Two templates were used to create models of the factor Xa protein and one template was used for dihydrofolate reductase from Plasmodium falciparum. Then, the relative free energies for several pairs of ligands were estimated using thermodynamic integration with th
